Beth Doran

Deficiency of the zinc finger protein ZPR1 causes neurodegeneration (2006)

Doran, Beth, Gherbesi, Norberto G., Hendricks, Gregory M., Flavell, Richard A., Davis, Roger J., Gangwani, Laxman

Mutations that cause reduced expression of the full-length Survival Motor Neurons (SMN) protein are a major cause of spinal muscular atrophy (SMA), a disease characterized by degeneration of the...

Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes (2005)

Jaeschke, Anja, Rincon, Mercedes, Doran, Beth, Reilly, Judith, Neuberg, Donna S., Greiner, Dale L., ...

The c-Jun NH(2)-terminal kinase isoform (JNK) 1 is implicated in type 2 diabetes. However, a potential role for the JNK2 protein kinase in diabetes has not been established. Here, we demonstrate that...

Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades (2005)

Brancho, Deborah Marie, Ventura, Juan-Jose, Jaeschke, Anja, Doran, Beth, Flavell, Richard A., Davis, Roger J.

Mixed-lineage protein kinase 3 (MLK3) is a member of the mitogen-activated protein (MAP) kinase kinase kinase group that has been implicated in multiple signaling cascades, including the NF-kappaB...

Expression of homocellular and heterocellular gap junctions in hamster arterioles and feed arteries (2003)

Sandow, Shaun L., Looft-Wilson, Robin, Doran, Beth, Grayson, T.Hilton, Segal, Steven S., Hill, Caryl E.

Objectives: Conduction of vasoconstrictor and vasodilator responses in the microcirculation involves electrical coupling through gap junction channels among cells of the vascular wall. The present...

Role of MLK3 in the Regulation of Mitogen-Activated Protein Kinase Signaling Cascades

Brancho, Deborah, Ventura, Juan-Jose, Jaeschke, Anja, Doran, Beth, Flavell, Richard A., Davis, Roger J.

Mixed-lineage protein kinase 3 (MLK3) is a member of the mitogen-activated protein (MAP) kinase kinase kinase group that has been implicated in multiple signaling cascades, including the NF-κB...

Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes

Jaeschke, Anja, Rincón, Mercedes, Doran, Beth, Reilly, Judith, Neuberg, Donna, Greiner, Dale L., ...

The c-Jun NH2-terminal kinase isoform (JNK) 1 is implicated in type 2 diabetes. However, a potential role for the JNK2 protein kinase in diabetes has not been established. Here, we demonstrate that...

Deficiency of the zinc finger protein ZPR1 causes neurodegeneration

Doran, Beth, Gherbesi, Norberto, Hendricks, Gregory, Flavell, Richard A., Davis, Roger J., Gangwani, Laxman

Mutations that cause reduced expression of the full-length Survival Motor Neurons (SMN) protein are a major cause of spinal muscular atrophy (SMA), a disease characterized by degeneration of the...

Role of MLK3 in the Regulation of Mitogen-Activated Protein Kinase Signaling Cascades

Brancho, Deborah, Ventura, Juan-Jose, Jaeschke, Anja, Doran, Beth, Flavell, Richard A., Davis, Roger J.

Mixed-lineage protein kinase 3 (MLK3) is a member of the mitogen-activated protein (MAP) kinase kinase kinase group that has been implicated in multiple signaling cascades, including the NF-κB...

Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes

Jaeschke, Anja, Rincón, Mercedes, Doran, Beth, Reilly, Judith, Neuberg, Donna, Greiner, Dale L., ...

The c-Jun NH2-terminal kinase isoform (JNK) 1 is implicated in type 2 diabetes. However, a potential role for the JNK2 protein kinase in diabetes has not been established. Here, we demonstrate that...

Deficiency of the zinc finger protein ZPR1 causes neurodegeneration

Doran, Beth, Gherbesi, Norberto, Hendricks, Gregory, Flavell, Richard A., Davis, Roger J., Gangwani, Laxman

Mutations that cause reduced expression of the full-length Survival Motor Neurons (SMN) protein are a major cause of spinal muscular atrophy (SMA), a disease characterized by degeneration of the...