Birgit Schittek

Long life span of tolerant T cells and the role of antigen in maintenance of peripheral tolerance (1995)

Alferink, Judith, Schittek, Birgit, Schönrich, Günter, Hämmerling, Günter J., Arnold, Bernd, Hünig, Th.

To follow the fate of tolerant T cells in vivowe used a transgenic mouse model in which peripheral T cell tolerance was based on a non-deletional mechanism. These mice expressed two transgenes: the...

Violation of allelic exclusion of the T cell receptor {beta} genes in a helper T cell clone (1989)

Schittek, Birgit, Unkelbach, Elvira, Rajewsky, Klaus, Radbruch, A

The 4-hydroxy-3-nltrophenylacetyl coupled to chicken gamma globulin specific and I-Ab restricted helper T cell clone IH4 carries a Vβ8 1–Dβ2.1–Jβ2.3-rearrangement on one and a...

Dermcidin-Derived Peptides Show a Different Mode of Action than the Cathelicidin LL-37 against Staphylococcus aureus▿

Senyürek, Ilknur, Paulmann, Maren, Sinnberg, Tobias, Kalbacher, Hubert, Deeg, Martin, Gutsmann, Thomas, ...

Dermcidin (DCD) is an antimicrobial peptide which is constitutively expressed in eccrine sweat glands. By postsecretory proteolytic processing in sweat, the DCD protein gives rise to anionic and...

Staphylococcus aureus Mutant Screen Reveals Interaction of the Human Antimicrobial Peptide Dermcidin with Membrane Phospholipids ▿

Li, Min, Rigby, Kevin, Lai, Yuping, Nair, Vinod, Peschel, Andreas, Schittek, Birgit, ...

Antimicrobial peptides (AMPs) form an important part of the innate host defense. In contrast to most AMPs, human dermcidin has an anionic net charge. To investigate whether bacteria have developed...