Brett A. McKinney

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction (2008)

Bush, William S, Edwards, Todd L, Dudek, Scott M, McKinney, Brett A, Ritchie, Marylyn D

Abstract Background Multifactor Dimensionality Reduction (MDR) has been introduced previously as a non-parametric statistical method for detecting gene-gene interactions. MDR performs a dimensional...

A Computational Model of Quantitative Chromatin Immunoprecipitation (ChIP) Analysis (2008)

Jingping Xie, Philip S. Crooke, Brett A. McKinney, Joel Soltman, Stephen J. Brandt

Chromatin immunoprecipitation (ChIP) analysis is widely used to identify the locations in genomes occupied by transcription factors (TFs). The approach involves chemical cross-linking of DNA with...

A Computational Model of Quantitative Chromatin Immunoprecipitation (ChIP) Analysis (2008)

Jingping Xie, Philip S. Crooke, Brett A. McKinney, Joel Soltman, Stephen J. Brandt

Chromatin immunoprecipitation (ChIP) analysis is widely used to identify the locations in genomes occupied by transcription factors (TFs). The approach involves chemical cross-linking of DNA with...

Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site

McKinney, Brett A, Kallewaard, Nicole L, Crowe, James E, Meiler, Jens

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

Bush, William S, Edwards, Todd L, Dudek, Scott M, McKinney, Brett A, Ritchie, Marylyn D

A Computational Model of Quantitative Chromatin Immunoprecipitation (ChIP) Analysis

Xie, Jingping, Crooke, Philip S., McKinney, Brett A., Soltman, Joel, Brandt, Stephen J.

Chromatin immunoprecipitation (ChIP) analysis is widely used to identify the locations in genomes occupied by transcription factors (TFs). The approach involves chemical cross-linking of DNA with...

Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis

McKinney, Brett A., Crowe, James E., Guo, Jingyu, Tian, Dehua

Evidence from human genetic studies of several disorders suggests that interactions between alleles at multiple genes play an important role in influencing phenotypic expression. Analytical methods...

The Quality of Chimpanzee T-Cell Activation and Simian Immunodeficiency Virus/Human Immunodeficiency Virus Susceptibility Achieved via Antibody-Mediated T-Cell Receptor/CD3 Stimulation Is a Function of the Anti-CD3 Antibody Isotype▿

Bibollet-Ruche, Frederic, McKinney, Brett A., Duverger, Alexandra, Wagner, Frederic H., Ansari, Aftab A., Kutsch, Olaf

While human immunodeficiency virus type 1 (HIV-1) infection is associated with hyperimmune activation and systemic depletion of CD4+ T cells, simian immunodeficiency virus (SIV) infection in sooty...