Brian A. Federici

Synthesis of Additional Endotoxins in Bacillus thuringiensis subsp. morrisoni PG-14 and Bacillus thuringiensis subsp. jegathesan Significantly Improves Their Mosquitocidal Efficacy (2005)

Hyun-woo Park, Dennis K. Bideshi, Brian A. Federici

A fundamental principal of resistance management is that the more complex and potent a toxin mixture, the slower resistance will develop to the mixture in an insect population. Thus, to develop more...

Synergy between Toxins of Bacillus thuringiensis subsp. israelensis and Bacillus sphaericus (2004)

Margaret C. Wirth, Joshua A. Jiannino, Brian A. Federici, William E. Walton

Synergistic interactions among the multiple endotoxins of Bacillus thuringiensis subsp. israelensis de Barjac play an important role in its high toxicity to mosquito larvae and the absence of...

Laboratory and Simulated Field Evaluation of a New Recombinant of Bacillus thuringiensis ssp. israelensis and Bacillus sphaericus against Culex Mosquito Larvae (Diptera: Culicidae) (2004)

Nayer S. Zahiri, Brian A. Federici, Mir S. Mulla

In the laboratory, three microbial mosquito larvicidal products consisting of Bacillus thuringiensis ssp. israelensis de Barjac (Bti), Bacillus sphaericus (Neide) (Bsph) (strain 2362), and the...

Cyt1A from Bacillus thuringiensis Restores Toxicity of Bacillus sphaericus Against Resistant Culex quinquefasciatus (Diptera: Culicidae) (2000)

Margaret C. Wirth, William E. Walton, Brian A. Federici

The 2362 strain of Bacillus sphaericus, which produces a binary toxin highly active against Culex mosquitoes, has been developed recently as a commercial larvicide. It is being used currently in...

Cyt1A from Bacillus thuringiensis Synergizes Activity of Bacillus sphaericus against Aedes aegypti (Diptera: Culicidae)

Wirth, Margaret C., Federici, Brian A., Walton, William E.

Bacillus sphaericus is a mosquitocidal bacterium recently developed as a commercial larvicide that is used worldwide to control pestiferous and vector mosquitoes. Whereas B. sphaericus is highly...

Molecular Genetic Manipulation of Truncated Cry1C Protein Synthesis in Bacillus thuringiensis To Improve Stability and Yield

Park, Hyun-Woo, Bideshi, Dennis K., Federici, Brian A.

Cry1 protoxins of Bacillus thuringiensis are insecticidal 135-kDa proteins synthesized and assembled into parasporal crystals during sporulation. After ingestion, these crystals dissolve in the...

Cyt1A from Bacillus thuringiensis Lacks Toxicity to Susceptible and Resistant Larvae of Diamondback Moth (Plutella xylostella) and Pink Bollworm (Pectinophora gossypiella)

Meyer, Susan K., Tabashnik, Bruce E., Liu, Yong-Biao, Wirth, Margaret C., Federici, Brian A.

We tested Cyt1Aa, a cytolytic endotoxin of Bacillus thuringiensis, against susceptible and Cry1A-resistant larvae of two lepidopteran pests, diamondback moth (Plutella xylostella) and pink bollworm...

Optimization of Cry3A Yields in Bacillus thuringiensis by Use of Sporulation-Dependent Promoters in Combination with the STAB-SD mRNA Sequence

Park, Hyun-Woo, Ge, Baoxue, Bauer, Leah S., Federici, Brian A.

The insecticidal activity of Bacillus thuringiensis strains toxic to coleopterous insects is due to Cry3 proteins assembled into small rectangular crystals. Toxin synthesis in these strains is...

Variable Cross-Resistance to Cry11B from Bacillus thuringiensis subsp. jegathesan in Culex quinquefasciatus (Diptera: Culicidae) Resistant to Single or Multiple Toxins of Bacillus thuringienisis subsp. israelensis

Wirth, Margaret C., Delécluse, Armelle, Federici, Brian A., Walton, William E.

A novel mosquitocidal bacterium, Bacillus thuringiensis subsp. jegathesan, and one of its toxins, Cry11B, in a recombinant B. thuringiensis strain were evaluated for cross-resistance with strains of...

Cyt1Aa Protein of Bacillus thuringiensis Is Toxic to the Cottonwood Leaf Beetle, Chrysomela scripta, and Suppresses High Levels of Resistance to Cry3Aa

Federici, Brian A., Bauer, Leah S.

The insecticidal activity of Bacillus thuringiensis is due primarily to Cry and Cyt proteins. Cry proteins are typically toxic to lepidopterous, coleopterous, or dipterous insects, whereas the known...

Effects of Substituting Granulin or a Granulin-Polyhedrin Chimera for Polyhedrin on Virion Occlusion and Polyhedral Morphology in Autographa californica Multinucleocapsid Nuclear Polyhedrosis Virus

Eason, Jane E., Hice, Robert H., Johnson, Jeffrey J., Federici, Brian A.

Substitution of granulin from the Trichoplusia ni granulosis virus (TnGV) for polyhedrin of the Autographa californica multinucleocapsid nuclear polyhedrosis virus (AcMNPV) yielded a few very large...

Recombinant Strain of Bacillus thuringiensis Producing Cyt1A, Cry11B, and the Bacillus sphaericus Binary Toxin

Park, Hyun-Woo, Bideshi, Dennis K., Federici, Brian A.

A novel recombinant Bacillus thuringiensis subsp. israelensis strain that produces the B. sphaericus binary toxin, Cyt1Aa, and Cry11Ba is described. The toxicity of this strain (50% lethal...

Rickettsia-Like Organism Causing Disease in a Crangonid Amphipod from Florida

Federici, Brian A., Hazard, Edwin I., Anthony, Darrell W.

A rickettsia-like organism causing high mortality and gross pathology has been found infecting over 40% of a population of the freshwater crustacean, Crangonyx (near) floridanus Bousfield, in...

Species-specific gating of gametangial dehiscence as a temporal reproductive isolating mechanism in Coelomomyces

Federici, Brian A.

Hybridzygotes of Coelomomyces dodgei and Coelomomyces punctatus can be produced in the laboratory by making reciprocal crosses of their gametes. Although the F1 hybrid sporophyte is viable, the F1...

Experimental hybridization of Coelomomyces dodgei and Coelomomyces punctatus

Federici, Brian A.

Two closely related fungi, Coelomomyces dodgei and C. punctatus (Chytridiomycetes; Blastocladiales), showing considerable potential for mosquito control, have been hybridized. Both species have life...

Enveloped double-stranded DNA insect virus with novel structure and cytopathology

Federici, Brian A.

An unusual type of virus has been isolated from larvae of the cabbage looper, Trichoplusia ni (Lepidoptera; Noctuidae). The virus infects a variety of tissues, including fat body, epidermis, and...

Cyt1A of Bacillus thuringiensis Delays Evolution of Resistance to Cry11A in the Mosquito Culex quinquefasciatus

Wirth, Margaret C., Park, Hyun-Woo, Walton, William E., Federici, Brian A.

Insecticides based on Bacillus thuringiensis subsp. israelensis have been used for mosquito and blackfly control for more than 20 years, yet no resistance to this bacterium has been reported....

A viral caspase contributes to modified apoptosis for virus transmission

Bideshi, Dennis K., Tan, Yeping, Bigot, Yves, Federici, Brian A.

The Spodoptera frugiperda ascovirus, a DNA virus that attacks lepidopterans, codes for an executioner caspase synthesized by 9 h after infection of Sf21 cells. This caspase alone induces apoptosis in...

Cyt1A from Bacillus thuringiensis Synergizes Activity of Bacillus sphaericus against Aedes aegypti (Diptera: Culicidae)

Wirth, Margaret C., Federici, Brian A., Walton, William E.

Bacillus sphaericus is a mosquitocidal bacterium recently developed as a commercial larvicide that is used worldwide to control pestiferous and vector mosquitoes. Whereas B. sphaericus is highly...

Molecular Genetic Manipulation of Truncated Cry1C Protein Synthesis in Bacillus thuringiensis To Improve Stability and Yield

Park, Hyun-Woo, Bideshi, Dennis K., Federici, Brian A.

Cry1 protoxins of Bacillus thuringiensis are insecticidal 135-kDa proteins synthesized and assembled into parasporal crystals during sporulation. After ingestion, these crystals dissolve in the...

Cyt1A from Bacillus thuringiensis Lacks Toxicity to Susceptible and Resistant Larvae of Diamondback Moth (Plutella xylostella) and Pink Bollworm (Pectinophora gossypiella)

Meyer, Susan K., Tabashnik, Bruce E., Liu, Yong-Biao, Wirth, Margaret C., Federici, Brian A.

We tested Cyt1Aa, a cytolytic endotoxin of Bacillus thuringiensis, against susceptible and Cry1A-resistant larvae of two lepidopteran pests, diamondback moth (Plutella xylostella) and pink bollworm...

Optimization of Cry3A Yields in Bacillus thuringiensis by Use of Sporulation-Dependent Promoters in Combination with the STAB-SD mRNA Sequence

Park, Hyun-Woo, Ge, Baoxue, Bauer, Leah S., Federici, Brian A.

The insecticidal activity of Bacillus thuringiensis strains toxic to coleopterous insects is due to Cry3 proteins assembled into small rectangular crystals. Toxin synthesis in these strains is...

Variable Cross-Resistance to Cry11B from Bacillus thuringiensis subsp. jegathesan in Culex quinquefasciatus (Diptera: Culicidae) Resistant to Single or Multiple Toxins of Bacillus thuringienisis subsp. israelensis

Wirth, Margaret C., Delécluse, Armelle, Federici, Brian A., Walton, William E.

A novel mosquitocidal bacterium, Bacillus thuringiensis subsp. jegathesan, and one of its toxins, Cry11B, in a recombinant B. thuringiensis strain were evaluated for cross-resistance with strains of...

Cyt1Aa Protein of Bacillus thuringiensis Is Toxic to the Cottonwood Leaf Beetle, Chrysomela scripta, and Suppresses High Levels of Resistance to Cry3Aa

Federici, Brian A., Bauer, Leah S.

The insecticidal activity of Bacillus thuringiensis is due primarily to Cry and Cyt proteins. Cry proteins are typically toxic to lepidopterous, coleopterous, or dipterous insects, whereas the known...

Effects of Substituting Granulin or a Granulin-Polyhedrin Chimera for Polyhedrin on Virion Occlusion and Polyhedral Morphology in Autographa californica Multinucleocapsid Nuclear Polyhedrosis Virus

Eason, Jane E., Hice, Robert H., Johnson, Jeffrey J., Federici, Brian A.

Substitution of granulin from the Trichoplusia ni granulosis virus (TnGV) for polyhedrin of the Autographa californica multinucleocapsid nuclear polyhedrosis virus (AcMNPV) yielded a few very large...

Recombinant Strain of Bacillus thuringiensis Producing Cyt1A, Cry11B, and the Bacillus sphaericus Binary Toxin

Park, Hyun-Woo, Bideshi, Dennis K., Federici, Brian A.

A novel recombinant Bacillus thuringiensis subsp. israelensis strain that produces the B. sphaericus binary toxin, Cyt1Aa, and Cry11Ba is described. The toxicity of this strain (50% lethal...

Rickettsia-Like Organism Causing Disease in a Crangonid Amphipod from Florida

Federici, Brian A., Hazard, Edwin I., Anthony, Darrell W.

A rickettsia-like organism causing high mortality and gross pathology has been found infecting over 40% of a population of the freshwater crustacean, Crangonyx (near) floridanus Bousfield, in...

Species-specific gating of gametangial dehiscence as a temporal reproductive isolating mechanism in Coelomomyces

Federici, Brian A.

Hybridzygotes of Coelomomyces dodgei and Coelomomyces punctatus can be produced in the laboratory by making reciprocal crosses of their gametes. Although the F1 hybrid sporophyte is viable, the F1...

Experimental hybridization of Coelomomyces dodgei and Coelomomyces punctatus

Federici, Brian A.

Two closely related fungi, Coelomomyces dodgei and C. punctatus (Chytridiomycetes; Blastocladiales), showing considerable potential for mosquito control, have been hybridized. Both species have life...

Enveloped double-stranded DNA insect virus with novel structure and cytopathology

Federici, Brian A.

An unusual type of virus has been isolated from larvae of the cabbage looper, Trichoplusia ni (Lepidoptera; Noctuidae). The virus infects a variety of tissues, including fat body, epidermis, and...

Cyt1A of Bacillus thuringiensis Delays Evolution of Resistance to Cry11A in the Mosquito Culex quinquefasciatus

Wirth, Margaret C., Park, Hyun-Woo, Walton, William E., Federici, Brian A.

Insecticides based on Bacillus thuringiensis subsp. israelensis have been used for mosquito and blackfly control for more than 20 years, yet no resistance to this bacterium has been reported....

A viral caspase contributes to modified apoptosis for virus transmission

Bideshi, Dennis K., Tan, Yeping, Bigot, Yves, Federici, Brian A.

The Spodoptera frugiperda ascovirus, a DNA virus that attacks lepidopterans, codes for an executioner caspase synthesized by 9 h after infection of Sf21 cells. This caspase alone induces apoptosis in...

Minireplicon from pBtoxis of Bacillus thuringiensis subsp. israelensis▿

Tang, Mujin, Bideshi, Dennis K., Park, Hyun-Woo, Federici, Brian A.

A 2.2-kb fragment containing a replicon from pBtoxis, the large plasmid that encodes the insecticidal endotoxins of Bacillus thuringiensis subsp. israelensis, was identified, cloned, and sequenced....

Genomic Sequence of Spodoptera frugiperda Ascovirus 1a, an Enveloped, Double-Stranded DNA Insect Virus That Manipulates Apoptosis for Viral Reproduction▿

Bideshi, Dennis K., Demattei, Marie-Véronique, Rouleux-Bonnin, Florence, Stasiak, Karine, Tan, Yeping, Bigot, Sylvie, ...

Ascoviruses (family Ascoviridae) are double-stranded DNA viruses with circular genomes that attack lepidopterans, where they produce large, enveloped virions, 150 by 400 nm, and cause a chronic,...

Mtx Toxins Synergize Bacillus sphaericus and Cry11Aa against Susceptible and Insecticide-Resistant Culex quinquefasciatus Larvae▿

Wirth, Margaret C., Yang, Yangkun, Walton, William E., Federici, Brian A., Berry, Colin

Two mosquitocidal toxins (Mtx) of Bacillus sphaericus, which are produced during vegetative growth, were investigated for their potential to increase toxicity and reduce the expression of insecticide...

Iteron-Binding ORF157 and FtsZ-Like ORF156 Proteins Encoded by pBtoxis Play a Role in Its Replication in Bacillus thuringiensis subsp. israelensis▿

Tang, Mujin, Bideshi, Dennis K., Park, Hyun-Woo, Federici, Brian A.

We recently identified a minireplicon of pBtoxis from Bacillus thuringiensis subsp. israelensis that contained an operon encoding two novel proteins (ORF156 and ORF157), both of which are required...

Novel Isolate of Bacillus thuringiensis subsp. thuringiensis That Produces a Quasicuboidal Crystal of Cry1Ab21 Toxic to Larvae of Trichoplusia ni▿

Swiecicka, Izabela, Bideshi, Dennis K., Federici, Brian A.

A new isolate (IS5056) of Bacillus thuringiensis subsp. thuringiensis that produces a novel variant of Cry1Ab, Cry1Ab21, was isolated from soil collected in northeastern Poland. Cry1Ab21 was composed...