Brian D. Robertson

Mycobacterial Mutants with Defective Control of Phagosomal Acidification (2005)

Graham R. Stewart, Janisha Patel, Brian D. Robertson, Aaron Rae, Douglas B. Young

The pathogenesis of mycobacterial infection is associated with an ability to interfere with maturation of the phagosomal compartment after ingestion by macrophages. Identification of the...

Tetracycline-inducible gene regulation in mycobacteria (2005)

Blokpoel, Marian C. J., Murphy, Helen N., O'Toole, Ronan, Wiles, Siouxsie, Runn, Ellen S. C., Stewart, Graham R., ...

A system for the tetracycline-inducible regulation of gene expression in mycobacteria has been developed. We have sub-cloned the tetRO region from the Corynebacterium glutamicum TetZ locus into a...

Military Proposals for Security Cooperation in the Asia Pacific Region. (1998)

Robertson, Brian D.

This paper suggests that there are unique opportunities to lay the foundation for future security cooperation in the Asia Pacific Region. Political forums are creating the environment conducive to...

A Postgenomic Approach to Identification of Mycobacterium leprae-Specific Peptides as T-Cell Reagents

Dockrell, Hazel M., Brahmbhatt, Shweta, Robertson, Brian D., Britton, Sven, Fruth, Uli, Gebre, Negussie, ...

To identify Mycobacterium leprae-specific human T-cell epitopes, which could be used to distinguish exposure to M. leprae from exposure to Mycobacterium tuberculosis or to environmental mycobacteria...

The Lipopolysaccharide Structures of Salmonella enterica Serovar Typhimurium and Neisseria gonorrhoeae Determine the Attachment of Human Mannose-Binding Lectin to Intact Organisms

Devyatyarova-Johnson, Marina, Rees, Ian H., Robertson, Brian D., Turner, Malcolm W., Klein, Nigel J., Jack, Dominic L.

Mannose-binding lectin (MBL) is an important component of the innate immune system. It binds to the arrays of sugars commonly presented by microorganisms and activates the complement system...

Tetracycline-inducible gene regulation in mycobacteria

Blokpoel, Marian C. J., Murphy, Helen N., O'Toole, Ronan, Wiles, Siouxsie, Runn, Ellen S. C., Stewart, Graham R., ...

A system for the tetracycline-inducible regulation of gene expression in mycobacteria has been developed. We have sub-cloned the tetRO region from the Corynebacterium glutamicum TetZ locus into a...

Alternative Luciferase for Monitoring Bacterial Cells under Adverse Conditions

Wiles, Siouxsie, Ferguson, Kathryn, Stefanidou, Martha, Young, Douglas B., Robertson, Brian D.

The availability of cloned luciferase genes from fireflies (luc) and from bacteria (luxAB) has led to the widespread use of bioluminescence as a reporter to measure cell viability and gene...

Mycobacterial Mutants with Defective Control of Phagosomal Acidification

Stewart, Graham R, Patel, Janisha, Robertson, Brian D, Rae, Aaron, Young, Douglas B

The pathogenesis of mycobacterial infection is associated with an ability to interfere with maturation of the phagosomal compartment after ingestion by macrophages. Identification of the...

A Postgenomic Approach to Identification of Mycobacterium leprae-Specific Peptides as T-Cell Reagents

Dockrell, Hazel M., Brahmbhatt, Shweta, Robertson, Brian D., Britton, Sven, Fruth, Uli, Gebre, Negussie, ...

To identify Mycobacterium leprae-specific human T-cell epitopes, which could be used to distinguish exposure to M. leprae from exposure to Mycobacterium tuberculosis or to environmental mycobacteria...

The Lipopolysaccharide Structures of Salmonella enterica Serovar Typhimurium and Neisseria gonorrhoeae Determine the Attachment of Human Mannose-Binding Lectin to Intact Organisms

Devyatyarova-Johnson, Marina, Rees, Ian H., Robertson, Brian D., Turner, Malcolm W., Klein, Nigel J., Jack, Dominic L.

Mannose-binding lectin (MBL) is an important component of the innate immune system. It binds to the arrays of sugars commonly presented by microorganisms and activates the complement system...

Tetracycline-inducible gene regulation in mycobacteria

Blokpoel, Marian C. J., Murphy, Helen N., O'Toole, Ronan, Wiles, Siouxsie, Runn, Ellen S. C., Stewart, Graham R., ...

A system for the tetracycline-inducible regulation of gene expression in mycobacteria has been developed. We have sub-cloned the tetRO region from the Corynebacterium glutamicum TetZ locus into a...

Alternative Luciferase for Monitoring Bacterial Cells under Adverse Conditions

Wiles, Siouxsie, Ferguson, Kathryn, Stefanidou, Martha, Young, Douglas B., Robertson, Brian D.

The availability of cloned luciferase genes from fireflies (luc) and from bacteria (luxAB) has led to the widespread use of bioluminescence as a reporter to measure cell viability and gene...

Mycobacterial Mutants with Defective Control of Phagosomal Acidification

Stewart, Graham R, Patel, Janisha, Robertson, Brian D, Rae, Aaron, Young, Douglas B

The pathogenesis of mycobacterial infection is associated with an ability to interfere with maturation of the phagosomal compartment after ingestion by macrophages. Identification of the...

Comparison of Mycobacterium Tuberculosis Genomes Reveals Frequent Deletions in a 20 kb Variable Region in Clinical Isolates

Ho, Timothy B. L., Robertson, Brian D., Taylor, G. Michael, Shaw, Rory J., Young, Douglas B.

The Mycobacterium tuberculosis complex is associated with a remarkably low level of structural gene polymorphism. As part of a search for alternative forms of genetic variation that may act as a...

Sensitive Detection of Gene Expression in Mycobacteria under Replicating and Non-Replicating Conditions Using Optimized Far-Red Reporters

Carroll, Paul, Schreuder, Lise J., Muwanguzi-Karugaba, Julian, Wiles, Siouxsie, Robertson, Brian D., Ripoll, Jorge, ...

Fluorescent reporter proteins have proven useful for imaging techniques in many organisms. We constructed optimized expression systems for several fluorescent proteins from the far-red region of the...