Brian E. Hawes

The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo

Kemp, E. Helen, Waterman, Elizabeth A., Hawes, Brian E., O’Neill, Kim, Gottumukkala, Raju V.S.R.K., Gawkrodger, David J., ...

Vitiligo is a common depigmenting disorder resulting from the loss of melanocytes in the skin. The pathogenesis of the disease remains obscure, although autoimmune mechanisms are thought to be...

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Garcia-Calvo, Margarita, Lisnock, JeanMarie, Bull, Herbert G., Hawes, Brian E., Burnett, Duane A., Braun, Matthew P., ...

Ezetimibe is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia, but its molecular target has been elusive. Using a genetic approach, we...

The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo

Kemp, E. Helen, Waterman, Elizabeth A., Hawes, Brian E., O’Neill, Kim, Gottumukkala, Raju V.S.R.K., Gawkrodger, David J., ...

Vitiligo is a common depigmenting disorder resulting from the loss of melanocytes in the skin. The pathogenesis of the disease remains obscure, although autoimmune mechanisms are thought to be...

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Garcia-Calvo, Margarita, Lisnock, JeanMarie, Bull, Herbert G., Hawes, Brian E., Burnett, Duane A., Braun, Matthew P., ...

Ezetimibe is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia, but its molecular target has been elusive. Using a genetic approach, we...