Cirimotich, Chris M, Scott, Jaclyn C, Phillips, Aaron T, Geiss, Brian J, Olson, Ken E
Abstract Background Arthropod-borne viruses (arboviruses) can persistently infect and cause limited damage to mosquito vectors. RNA interference (RNAi) is a mosquito antiviral response important in...
Bmc Microbiology, Christopher M Cirimotich, Jaclyn C Scott, Aaron T Phillips, Brian J Geiss, Ken E Olson, ...
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Recombination-ready Sindbis replicon expression vectors for transgene expression (2007)
Geiss, Brian J, Shimonkevitz, Lisa H, Sackal, Cherilyn I, Olson, Ken E
Abstract Background Sindbis viruses have been widely used as tools to study gene function in cells. Despite the utility of these systems, the construction and production of alphavirus replicons is...
Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA (2005)
Geiss, Brian J, Pierson, Theodore C, Diamond, Michael S
Abstract Background West Nile virus is an emerging human pathogen for which specific antiviral therapy has not been developed. Recent studies have suggested that RNA interference (RNAi) has...
Geiss, Brian J., Smith, Tracy J., Leib, David A., Morrison, Lynda A.
The virion host shutoff (vhs) protein encoded by herpes simplex virus type 1 (HSV-1) destabilizes both viral and host mRNAs. An HSV-1 strain with a mutation in vhs is attenuated in virulence and...
Temporal Regulation of Herpes Simplex Virus Type 2 VP22 Expression and Phosphorylation
Geiss, Brian J., Tavis, John E., Metzger, Lisa M., Leib, David A., Morrison, Lynda A.
The VP22 protein of herpes simplex virus type 2 (HSV-2) is a major component of the virion tegument. Previous work with HSV-1 indicated that VP22 is phosphorylated during infection, and...
Geiss, Brian J., Smith, Tracy J., Leib, David A., Morrison, Lynda A.
The virion host shutoff (vhs) protein encoded by herpes simplex virus type 1 (HSV-1) destabilizes both viral and host mRNAs. An HSV-1 strain with a mutation in vhs is attenuated in virulence and...
Temporal Regulation of Herpes Simplex Virus Type 2 VP22 Expression and Phosphorylation
Geiss, Brian J., Tavis, John E., Metzger, Lisa M., Leib, David A., Morrison, Lynda A.
The VP22 protein of herpes simplex virus type 2 (HSV-2) is a major component of the virion tegument. Previous work with HSV-1 indicated that VP22 is phosphorylated during infection, and...