Martin, Olivier, Valsesia, Armand, Telenti, Amalio, Xenarios, Ioannis, Stevenson, Brian J.
Summary: We present a tool designed for visualization of large-scale genetic and genomic data exemplified by results from genome-wide association studies. This software provides an integrated...
Rapid evolution of cancer/testis genes on the X chromosome (2007)
Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, ...
Abstract Background Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding that many CT...
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Abstract Introduction Diverse microarray and sequencing technologies have been widely used to characterise the molecular changes in malignant epithelial cells in breast cancers. Such gene expression...
IS THERE COGNITIVE IMPAIRMENT IN CLINICALLY 'HEALTHY' ABSTINENT ALCOHOL DEPENDENCE? (2005)
DAVIES, SIMON J. C., PANDIT, SMITA A., FEENEY, ADRIAN, STEVENSON, BRIAN J., KERWIN, ROBERT W., NUTT, DAVID J., ...
Aims: The aim of this study was to determine neuropsychological performance in apparently cognitively, mentally, and physically healthy abstinent alcohol-dependent subjects compared with control...
An atlas of human gene expression from massively parallel signature sequencing (MPSS) (2005)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
IS THERE COGNITIVE IMPAIRMENT IN CLINICALLY 'HEALTHY' ABSTINENT ALCOHOL DEPENDENCE? (2005)
DAVIES, SIMON J. C., PANDIT, SMITA A., FEENEY, ADRIAN, STEVENSON, BRIAN J., KERWIN, ROBERT W., NUTT, DAVID J., ...
Aims: The aim of this study was to determine neuropsychological performance in apparently cognitively, mentally, and physically healthy abstinent alcohol-dependent subjects compared with control...
trome, trEST and trGEN: databases of predicted protein sequences (2004)
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
Long-Range Heterogeneity at the 3' Ends of Human mRNAs (2002)
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
Long-Range Heterogeneity at the 3' Ends of Human mRNAs (2002)
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
Stevenson, Brian J., Hagenbüchle, Otto, Wellauer, Peter K.
Elastase II and trypsin mRNAs were cloned 1n form of their cDNAs from pancreas of strain A/J mice, and their complete nucleotide sequences were determined. The elastase II mRNA 1s 912 nucleotides...
Specific Sterols Required for the Internalization Step of Endocytosis in Yeast
Munn, Alan L., Heese-Peck, Antje, Stevenson, Brian J., Pichler, Harald, Riezman, Howard
Sterols are major components of the plasma membrane, but their functions in this membrane are not well understood. We isolated a mutant defective in the internalization step of endocytosis in a gene...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Long-Range Heterogeneity at the 3′ Ends of Human mRNAs
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
The publication of a draft of the human genome and of large collections of transcribed sequences has made it possible to study the complex relationship between the transcriptome and the genome. In...
Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae
Zanolari, Bettina, Friant, Sylvie, Funato, Kouichi, Sütterlin, Christine, Stevenson, Brian J., Riezman, Howard
The internalization step of endocytosis in yeast requires actin and sterols for maximum efficiency. In addition, many receptors and plasma membrane proteins must be phosphorylated and ubiquitylated...
Brentani, Helena, Caballero, Otávia L., Camargo, Anamaria A., Da Silva, Aline M., Da Silva, Wilson Araújo, Neto, Emmanuel Dias, ...
Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the...
trome, trEST and trGEN: databases of predicted protein sequences
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
Identification of cancer/testis-antigen genes by massively parallel signature sequencing
Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., ...
Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS tags can be unambiguously assigned to...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Specific Sterols Required for the Internalization Step of Endocytosis in Yeast
Munn, Alan L., Heese-Peck, Antje, Stevenson, Brian J., Pichler, Harald, Riezman, Howard
Sterols are major components of the plasma membrane, but their functions in this membrane are not well understood. We isolated a mutant defective in the internalization step of endocytosis in a gene...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Long-Range Heterogeneity at the 3′ Ends of Human mRNAs
Iseli, Christian, Stevenson, Brian J., De Souza, Sandro J., Samaia, Helena B., Camargo, Anamaria A., Buetow, Kenneth H., ...
The publication of a draft of the human genome and of large collections of transcribed sequences has made it possible to study the complex relationship between the transcriptome and the genome. In...
Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae
Zanolari, Bettina, Friant, Sylvie, Funato, Kouichi, Sütterlin, Christine, Stevenson, Brian J., Riezman, Howard
The internalization step of endocytosis in yeast requires actin and sterols for maximum efficiency. In addition, many receptors and plasma membrane proteins must be phosphorylated and ubiquitylated...
Brentani, Helena, Caballero, Otávia L., Camargo, Anamaria A., Da Silva, Aline M., Da Silva, Wilson Araújo, Neto, Emmanuel Dias, ...
Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the...
trome, trEST and trGEN: databases of predicted protein sequences
Sperisen, Peter, Iseli, Christian, Pagni, Marco, Stevenson, Brian J., Bucher, Philipp, Jongeneel, C. Victor
We previously introduced two new protein databases (trEST and trGEN) of hypothetical protein sequences predicted from EST and HTG sequences, respectively. Here, we present the updates made on these...
Identification of cancer/testis-antigen genes by massively parallel signature sequencing
Chen, Yao-Tseng, Scanlan, Matthew J., Venditti, Charis A., Chua, Ramon, Theiler, Gregory, Stevenson, Brian J., ...
Massively parallel signature sequencing (MPSS) generates millions of short sequence tags corresponding to transcripts from a single RNA preparation. Most MPSS tags can be unambiguously assigned to...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Rapid evolution of cancer/testis genes on the X chromosome
Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, ...
Genome-wide analysis of cancer/testis gene expression
Hofmann, Oliver, Caballero, Otavia L., Stevenson, Brian J., Chen, Yao-Tseng, Cohen, Tzeela, Chua, Ramon, ...
Cancer/Testis (CT) genes, normally expressed in germ line cells but also activated in a wide range of cancer types, often encode antigens that are immunogenic in cancer patients, and present...
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line
Zhao, Qi, Caballero, Otavia L., Levy, Samuel, Stevenson, Brian J., Iseli, Christian, De Souza, Sandro J., ...
We have identified new genomic alterations in the breast cancer cell line HCC1954, using high-throughput transcriptome sequencing. With 120 Mb of cDNA sequences, we were able to identify genomic...
Martin, Olivier, Valsesia, Armand, Telenti, Amalio, Xenarios, Ioannis, Stevenson, Brian J.
Summary: We present a tool designed for visualization of large-scale genetic and genomic data exemplified by results from genome-wide association studies. This software provides an integrated...