Brigitte Sigal-Zafrani

Tumor aromatase expression as a prognostic factor for local control in young breast cancer patients after breast-conserving treatment (2009)

Bollet, Marc A, Savignoni, Alexia, De Koning, Leanne, Tran-Perennou, Carine, Barbaroux, Catherine, Degeorges, Armelle, ...

Abstract Introduction We sought to determine whether the levels of expression of 17 candidate genes were associated with locoregional control after breast-conserving treatments of early-stage breast...

High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers (2008)

Bollet, Marc A., Servant, Nicolas, Neuvial, Pierre, Decraene, Charles, Lebigot, Ingrid, Meyniel, Jean-Philippe, ...

Background To distinguish new primary breast cancers from true recurrences, pangenomic analyses of DNA copy number alterations (CNAs) using single-nucleotide polymorphism arrays have proven useful. ...

Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity (2007)

Vincent-Salomon, Anne, Gruel, Nadège, Lucchesi, Carlo, MacGrogan, Gaëtan, Dendale, Remi, Sigal-Zafrani, Brigitte, ...

Abstract Introduction Typical medullary breast carcinoma (MBC) has recently been recognized to be part of the basal-like carcinoma spectrum, a feature in agreement with the high rate of TP53...

Risk of Second Non Breast Malignancies (SNBM) in Relation to Brca1 And Brca2 Mutation Status Following Breast-Conserving Surgery and Radiotherapy (2006)

Alain Fourquet,, Alexia Savignoni,, Brigitte Sigal-Zafrani

Women from hereditary breast cancer families with BRCA1/2 germline mutation are atincreased risk for contralateral breast cancer (BC) and for ovarian cancer (OC). It is less clear whethermutation...

Enrichment methods to detect bone marrow micrometastases in breast carcinoma patients: clinical relevance (2004)

Choesmel, Valérie, Pierga, Jean-Yves, Nos, Claude, Vincent-Salomon, Anne, Sigal-Zafrani, Brigitte, Thiery, Jean-Paul, ...

Abstract Introduction Improving technologies for the detection and purification of bone marrow (BM) micrometastatic cells in breast cancer patients should lead to earlier prognosis of the risk of...