Britta Mersch

Publication List Details

Period

2007 - 2009

Number

11

Co-Authors

SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements (2008)

Mersch, Britta, Sela, Noa, Ast, Gil, Suhai, Sandor

Background: Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts...

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome (2008)

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Ast, Gil

Background: Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome and the...

Automatic detection of exonic splicing enhancers (ESEs) using SVMs (2008)

Mersch, Britta, Gepperth, Alexander, Suhai, Sándor, Hotz-Wagenblatt, Agnes

Abstract Background Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for SR proteins....

Gradient-based Optimization of Kernel-Target Alignment for Sequence Kernels Applied to Bacterial Gene Start Detection (2008)

Christian Igel, Tobias Glasmachers, Britta Mersch, Nico Pfeifer, Peter Meinicke

Biological data mining using kernel methods can be improved by a task-specific choice of the kernel function. Oligo kernels for genomic sequence analysis have proven to have a high discriminative...

SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements (2007)

Mersch, Britta, Sela, Noa, Ast, Gil, Suhai, Sándor, Hotz-Wagenblatt, Agnes

Abstract Background Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization ), or the...

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome (2007)

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Hotz-Wagenblatt, Agnes, Ast, Gil

Abstract Background Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome...

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Hotz-Wagenblatt, Agnes, Ast, Gil

Analysis of transposed elements in the human and mouse genomes reveals many effects on the transcriptomes, including a higher level of exonization of Alu elements than other elements.