I. WELCOME TO THE MORASS 1 (2009)
Version 2.5 A program originally conceived and developed by
Craig R. Bush, Jennifer M. Havens, Brian M. Necela, Weidong Su, Lu Chen, Masahiro Yanagisawa, ...
and anchorage-independent growth and invasion through Matrigel-coated transwell membranes. We carried out a longitudinal two-class microarray analysis in which mRNA abundance was measured as a...
John A. Copland, Peter J. Davies, Gregory L. Shipley, Christopher G. Wood, Bruce A. Luxon, Randall J. Urban
The advent of gene array technology brings the ability to classify disease states to the molecular level by examining changes in all mRNAs expressed in cells or tissues. Comparing changes in gene...
Contents I. WELCOME TO THE MORASS 1 (2007)
Bruce A. Luxon, David G. Gorenstein
Version 2.5 A program originally conceived and developed by
Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers (2003)
Yang, Xianbin, Li, Xin, Prow, Tarl W., Reece, Lisa M., Bassett, Suzanne E., Luxon, Bruce A., ...
An immunofluorescence assay was developed to identify proteins specifically binding to oligonucleoside phosphorodithioate (ODN) aptamers from a bead‐bound ODN library. Accordingly, NF‐κB...
Yang, Xianbin, Bassett, Suzanne E., Li, Xin, Luxon, Bruce A., Herzog, Norbert K., Shope, Robert E., ...
Chemically synthesized combinatorial libraries of unmodified or modified nucleic acids have not previously been used in methods to rapidly select oligonucleotides binding to target biomolecules such...
Zhang, Yuhong, Luxon, Bruce A., Casola, Antonella, Garofalo, Roberto P., Jamaluddin, Mohammad, Brasier, Allan R.
The Paramyxovirus respiratory syncytial virus (RSV) is the primary etiologic agent of serious epidemic lower respiratory tract disease in infants, immunosuppressed patients, and the elderly. Lower...
Identification of NF-κB-Dependent Gene Networks in Respiratory Syncytial Virus-Infected Cells
Tian, Bing, Zhang, Yuhong, Luxon, Bruce A., Garofalo, Roberto P., Casola, Antonella, Sinha, Mala, ...
Respiratory syncytial virus (RSV) is a mucosa-restricted virus that is a leading cause of epidemic respiratory tract infections in children. In epithelial cells, RSV replication activates nuclear...
Yang, Xianbin, Bassett, Suzanne E., Li, Xin, Luxon, Bruce A., Herzog, Norbert K., Shope, Robert E., ...
Chemically synthesized combinatorial libraries of unmodified or modified nucleic acids have not previously been used in methods to rapidly select oligonucleotides binding to target biomolecules such...
Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers
Yang, Xianbin, Li, Xin, Prow, Tarl W., Reece, Lisa M., Bassett, Suzanne E., Luxon, Bruce A., ...
An immunofluorescence assay was developed to identify proteins specifically binding to oligonucleoside phosphorodithioate (ODN) aptamers from a bead-bound ODN library. Accordingly, NF-κB p50 protein...
Scholle, Frank, Li, Kui, Bodola, Francis, Ikeda, Masanori, Luxon, Bruce A., Lemon, Stanley M.
Considerable controversy surrounds the impact of hepatitis C virus (HCV) protein expression on viability of host cells and regulation of the cell cycle. Both promotion of cellular proliferation and...
Zhang, Jian-zhi, Sinha, Mala, Luxon, Bruce A., Yu, Xue-jie
Ehrlichia chaffeensis is an obligatory intracellular bacterium which resides in an early endosome in monocytes. E. chaffeensis infection in a human monocyte cell line (THP1) significantly altered the...
Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in Chimpanzees†
Bigger, Catherine B., Guerra, Bernadette, Brasky, Kathleen M., Hubbard, Gene, Beard, Michael R., Luxon, Bruce A., ...
Hepatitis C virus (HCV) infections represent a global health problem and are a major contributor to end-stage liver disease including cirrhosis and hepatocellular carcinoma. An improved understanding...
Zhang, Yuhong, Luxon, Bruce A., Casola, Antonella, Garofalo, Roberto P., Jamaluddin, Mohammad, Brasier, Allan R.
The Paramyxovirus respiratory syncytial virus (RSV) is the primary etiologic agent of serious epidemic lower respiratory tract disease in infants, immunosuppressed patients, and the elderly. Lower...
Identification of NF-κB-Dependent Gene Networks in Respiratory Syncytial Virus-Infected Cells
Tian, Bing, Zhang, Yuhong, Luxon, Bruce A., Garofalo, Roberto P., Casola, Antonella, Sinha, Mala, ...
Respiratory syncytial virus (RSV) is a mucosa-restricted virus that is a leading cause of epidemic respiratory tract infections in children. In epithelial cells, RSV replication activates nuclear...
Yang, Xianbin, Bassett, Suzanne E., Li, Xin, Luxon, Bruce A., Herzog, Norbert K., Shope, Robert E., ...
Chemically synthesized combinatorial libraries of unmodified or modified nucleic acids have not previously been used in methods to rapidly select oligonucleotides binding to target biomolecules such...
Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers
Yang, Xianbin, Li, Xin, Prow, Tarl W., Reece, Lisa M., Bassett, Suzanne E., Luxon, Bruce A., ...
An immunofluorescence assay was developed to identify proteins specifically binding to oligonucleoside phosphorodithioate (ODN) aptamers from a bead-bound ODN library. Accordingly, NF-κB p50 protein...
Scholle, Frank, Li, Kui, Bodola, Francis, Ikeda, Masanori, Luxon, Bruce A., Lemon, Stanley M.
Considerable controversy surrounds the impact of hepatitis C virus (HCV) protein expression on viability of host cells and regulation of the cell cycle. Both promotion of cellular proliferation and...
Zhang, Jian-zhi, Sinha, Mala, Luxon, Bruce A., Yu, Xue-jie
Ehrlichia chaffeensis is an obligatory intracellular bacterium which resides in an early endosome in monocytes. E. chaffeensis infection in a human monocyte cell line (THP1) significantly altered the...
Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in Chimpanzees†
Bigger, Catherine B., Guerra, Bernadette, Brasky, Kathleen M., Hubbard, Gene, Beard, Michael R., Luxon, Bruce A., ...
Hepatitis C virus (HCV) infections represent a global health problem and are a major contributor to end-stage liver disease including cirrhosis and hepatocellular carcinoma. An improved understanding...
Differential Signaling Networks Induced by Mild and Lethal Hemorrhagic Fever Virus Infections†
Bowick, Gavin C., Fennewald, Susan M., Elsom, Barry L., Aronson, Judith F., Luxon, Bruce A., Gorenstein, David G., ...
The family Arenaviridae includes several National Institutes of Allergy and Infections Diseases category A select agents which cause hemorrhagic fever. There are few vaccines available, and treatment...
Stochastic Regulation in Early Immune Response
Lipniacki, Tomasz, Paszek, Pawel, Brasier, Allan R., Luxon, Bruce A., Kimmel, Marek
Living cells may be considered noisy or stochastic biochemical reactors. In eukaryotic cells, in which the number of protein or mRNA molecules is relatively large, the stochastic effects originate...
Bowick, Gavin C., Fennewald, Susan M., Scott, Erin P., Zhang, LiHong, Elsom, Barry L., Aronson, Judith F., ...
Phosphorylation plays a key role in regulating many signaling pathways. Although studies investigating the phosphorylated forms of signaling pathways are now commonplace, global analysis of protein...
CadA Negatively Regulates Escherichia coli O157:H7 Adherence and Intestinal Colonization▿ †
Vazquez-Juarez, Roberto C., Kuriakose, Jeeba A., Rasko, David A., Ritchie, Jennifer M., Kendall, Melissa M., Slater, Terry M., ...
Adherence of pathogenic Escherichia coli strains to intestinal epithelia is essential for infection. For enterohemorrhagic E. coli (EHEC) serotype O157:H7, we have previously demonstrated that...
Bowick, Gavin C., Spratt, Heidi M., Hogg, Alison E., Endsley, Janice J., Wiktorowicz, John E., Kurosky, Alexander, ...
Arenaviruses are important emerging pathogens and include a number of hemorrhagic fever viruses classified as NIAID category A priority pathogens and CDC potential biothreat agents. Infection of...