Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine (2005)
Nat F. Brown, Bruce A. Vallance, Brian K. Coombes, Yanet Valdez, Bryan A. Coburn, B. Brett Finlay
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine (2005)
Brown, Nathaniel Francis, Vallance, Bruce A., Coombes, Brian K., Vandez, Yanet, Coburn, Bryan A., Finlay, B. Brett
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine (2005)
Brown, Nathaniel Francis, Vallance, Bruce A., Coombes, Brian K., Vandez, Yanet, Coburn, Bryan A., Finlay, B. Brett
Yes
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine (2005)
Brown, Nathaniel Francis, Vallance, Bruce A., Coombes, Brian K., Vandez, Yanet, Coburn, Bryan A., Finlay, B. Brett
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine (2005)
Brown, Nathaniel Francis, Vallance, Bruce A., Coombes, Brian K., Vandez, Yanet, Coburn, Bryan A., Finlay, B. Brett
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Maaser, Christian, Housley, Michael P., Iimura, Mitsutoshi, Smith, Jennifer R., Vallance, Bruce A., Finlay, B. Brett, ...
Citrobacter rodentium, a murine model pathogen for human enteropathogenic Escherichia coli, predominantly colonizes the lumen and mucosal surface of the colon and cecum and causes crypt hyperplasia...
Coombes, Brian K., Brown, Nathaniel Francis, Kujat-Choy, Sonya, Vallance, Bruce A., Finlay, B. Brett
The Salmonella pathogenicity island-2 (SPI2) is a virulence locus on the bacterial chromosome required for intracellular proliferation and systemic infection in mice. Cell culture models and a murine...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Coombes, Brian K., Brown, Nathaniel Francis, Kujat-Choy, Sonya, Vallance, Bruce A., Finlay, B. Brett
The Salmonella pathogenicity island-2 (SPI2) is a virulence locus on the bacterial chromosome required for intracellular proliferation and systemic infection in mice. Cell culture models and a murine...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Coombes, Brian K., Brown, Nathaniel Francis, Kujat-Choy, Sonya, Vallance, Bruce A., Finlay, B. Brett
The Salmonella pathogenicity island-2 (SPI2) is a virulence locus on the bacterial chromosome required for intracellular proliferation and systemic infection in mice. Cell culture models and a murine...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Coombes, Brian K., Brown, Nathaniel Francis, Kujat-Choy, Sonya, Vallance, Bruce A., Finlay, B. Brett
The Salmonella pathogenicity island-2 (SPI2) is a virulence locus on the bacterial chromosome required for intracellular proliferation and systemic infection in mice. Cell culture models and a murine...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
The immunomodulation of intestinal smooth muscle function (1999)
In response to an enteric infection, the host mobilizes inflammatory and immune cells to combat the invading pathogen. Studies suggest that physiologic tissues such as smooth muscle are also...
Vallance, Bruce A., Galeazzi, Francesca, Collins, Stephen M., Snider, Denis P.
Expulsion of intestinal nematode parasites and the associated increased contraction by intestinal muscle are T cell dependent, since both are attenuated in athymic rodents. The CD4 T-cell subset has...
De Grado, Myriam, Rosenberger, Carrie M., Gauthier, Annick, Vallance, Bruce A., Finlay, B. Brett
Enteropathogenic Escherichia coli (EPEC) is an extracellular bacterial pathogen that infects the human intestinal epithelium and is a major cause of infantile diarrhea in developing countries. EPEC...
Deng, Wanyin, Li, Yuling, Vallance, Bruce A., Finlay, B. Brett
The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains a significant...
Vallance, Bruce A., Deng, Wanyin, Knodler, Leigh A., Finlay, B. Brett
The bacterial pathogen Citrobacter rodentium belongs to a family of gastrointestinal pathogens that includes enteropathogenic and enterohemorrhagic Escherichia coli and is the causative agent of...
Vallance, Bruce A., Deng, Wanyin, De Grado, Myriam, Chan, Crystal, Jacobson, Kevan, Finlay, B. Brett
Citrobacter rodentium belongs to the attaching and effacing family of enteric bacterial pathogens that includes both enteropathogenic and enterohemorrhagic Escherichia coli. These bacteria infect...
Zaharik, Michelle L., Vallance, Bruce A., Puente, José L., Gros, Philippe, Finlay, B. Brett
Nramp1 (Natural resistance-associated macrophage protein-1; also known as Slc11a1) is a host resistance gene that provides protection against several intracellular pathogens, including Salmonella...
Host Susceptibility to the Attaching and Effacing Bacterial Pathogen Citrobacter rodentium
Vallance, Bruce A., Deng, Wanyin, Jacobson, Kevan, Finlay, B. Brett
Many studies have shown that genetic susceptibility plays a key role in determining whether bacterial pathogens successfully infect and cause disease in potential hosts. Surprisingly, whether host...
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Maaser, Christian, Housley, Michael P., Iimura, Mitsutoshi, Smith, Jennifer R., Vallance, Bruce A., Finlay, B. Brett, ...
Citrobacter rodentium, a murine model pathogen for human enteropathogenic Escherichia coli, predominantly colonizes the lumen and mucosal surface of the colon and cecum and causes crypt hyperplasia...
SseK1 and SseK2 Are Novel Translocated Proteins of Salmonella enterica Serovar Typhimurium
Kujat Choy, Sonya L., Boyle, Erin C., Gal-Mor, Ohad, Goode, David L., Valdez, Yanet, Vallance, Bruce A., ...
Salmonella enterica is a gram-negative, facultative intracellular pathogen that causes disease symptoms ranging from gastroenteritis to typhoid fever. A key virulence strategy is the translocation of...
Hardwidge, Philip R., Deng, Wanyin, Vallance, Bruce A., Rodriguez-Escudero, Isabel, Cid, Victor J., Molina, Maria, ...
EspG is a conserved protein encoded by the locus of enterocyte effacement (LEE) of attaching and effacing (A/E) pathogens, including enteropathogenic and enterohemorrhagic Escherichia coli and...
Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...
Knodler, Leigh A., Bestor, Aaron, Ma, Caixia, Hansen-Wester, Imke, Hensel, Michael, Vallance, Bruce A., ...
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar...
Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine
Brown, Nat F, Vallance, Bruce A, Coombes, Brian K, Valdez, Yanet, Coburn, Bryan A, Finlay, B. Brett
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Khan, Mohammed A., Ma, Caixia, Knodler, Leigh A., Valdez, Yanet, Rosenberger, Carrie M., Deng, Wanyin, ...
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are noninvasive bacterial pathogens that infect their hosts' intestinal epithelium, causing severe diarrheal disease....
Vallance, Bruce A., Galeazzi, Francesca, Collins, Stephen M., Snider, Denis P.
Expulsion of intestinal nematode parasites and the associated increased contraction by intestinal muscle are T cell dependent, since both are attenuated in athymic rodents. The CD4 T-cell subset has...
De Grado, Myriam, Rosenberger, Carrie M., Gauthier, Annick, Vallance, Bruce A., Finlay, B. Brett
Enteropathogenic Escherichia coli (EPEC) is an extracellular bacterial pathogen that infects the human intestinal epithelium and is a major cause of infantile diarrhea in developing countries. EPEC...
Deng, Wanyin, Li, Yuling, Vallance, Bruce A., Finlay, B. Brett
The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains a significant...
Vallance, Bruce A., Deng, Wanyin, Knodler, Leigh A., Finlay, B. Brett
The bacterial pathogen Citrobacter rodentium belongs to a family of gastrointestinal pathogens that includes enteropathogenic and enterohemorrhagic Escherichia coli and is the causative agent of...
Vallance, Bruce A., Deng, Wanyin, De Grado, Myriam, Chan, Crystal, Jacobson, Kevan, Finlay, B. Brett
Citrobacter rodentium belongs to the attaching and effacing family of enteric bacterial pathogens that includes both enteropathogenic and enterohemorrhagic Escherichia coli. These bacteria infect...
Zaharik, Michelle L., Vallance, Bruce A., Puente, José L., Gros, Philippe, Finlay, B. Brett
Nramp1 (Natural resistance-associated macrophage protein-1; also known as Slc11a1) is a host resistance gene that provides protection against several intracellular pathogens, including Salmonella...
Host Susceptibility to the Attaching and Effacing Bacterial Pathogen Citrobacter rodentium
Vallance, Bruce A., Deng, Wanyin, Jacobson, Kevan, Finlay, B. Brett
Many studies have shown that genetic susceptibility plays a key role in determining whether bacterial pathogens successfully infect and cause disease in potential hosts. Surprisingly, whether host...
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Maaser, Christian, Housley, Michael P., Iimura, Mitsutoshi, Smith, Jennifer R., Vallance, Bruce A., Finlay, B. Brett, ...
Citrobacter rodentium, a murine model pathogen for human enteropathogenic Escherichia coli, predominantly colonizes the lumen and mucosal surface of the colon and cecum and causes crypt hyperplasia...
SseK1 and SseK2 Are Novel Translocated Proteins of Salmonella enterica Serovar Typhimurium
Kujat Choy, Sonya L., Boyle, Erin C., Gal-Mor, Ohad, Goode, David L., Valdez, Yanet, Vallance, Bruce A., ...
Salmonella enterica is a gram-negative, facultative intracellular pathogen that causes disease symptoms ranging from gastroenteritis to typhoid fever. A key virulence strategy is the translocation of...
Hardwidge, Philip R., Deng, Wanyin, Vallance, Bruce A., Rodriguez-Escudero, Isabel, Cid, Victor J., Molina, Maria, ...
EspG is a conserved protein encoded by the locus of enterocyte effacement (LEE) of attaching and effacing (A/E) pathogens, including enteropathogenic and enterohemorrhagic Escherichia coli and...
Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...
Knodler, Leigh A., Bestor, Aaron, Ma, Caixia, Hansen-Wester, Imke, Hensel, Michael, Vallance, Bruce A., ...
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar...
Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine
Brown, Nat F, Vallance, Bruce A, Coombes, Brian K, Valdez, Yanet, Coburn, Bryan A, Finlay, B. Brett
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the...
Khan, Mohammed A., Ma, Caixia, Knodler, Leigh A., Valdez, Yanet, Rosenberger, Carrie M., Deng, Wanyin, ...
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are noninvasive bacterial pathogens that infect their hosts' intestinal epithelium, causing severe diarrheal disease....
Zaharik, Michelle L, Nayar, Tarun, White, Rick, Ma, Caixia, Vallance, Bruce A, Straka, Nadine, ...
Chlamydia trachomatis is a major cause of sexually transmitted disease worldwide for which an effective vaccine is being actively pursued. Current vaccine efforts will be aided by elucidating the...
Gal-Mor, Ohad, Gibson, Deanna L., Baluta, Dan, Vallance, Bruce A., Finlay, B. Brett
Salmonella spp. are Gram-negative enteropathogenic bacteria that infect a variety of vertebrate hosts. Like any other living organism, protein secretion is a fundamental process essential for various...
Bergstrom, Kirk S. B., Guttman, Julian A., Rumi, Mohammad, Ma, Caixia, Bouzari, Saied, Khan, Mohammed A., ...
The attaching and effacing (A/E) bacterial pathogens enteropathogenic Escherichia coli and enterohemorrhagic E. coli and the related mouse pathogen Citrobacter rodentium colonize their hosts'...
Khan, Mohammed A., Bouzari, Saeid, Ma, Caixia, Rosenberger, Carrie M., Bergstrom, Kirk S. B., Gibson, Deanna L., ...
Enteropathogenic Escherichia coli (EPEC) and the murine pathogen Citrobacter rodentium belong to the attaching and effacing (A/E) family of bacterial pathogens. These noninvasive bacteria infect...