Bruce AJ Ponder

Common variants in the ATM, BRCA1, BRCA2, CHEK2and TP53cancer susceptibility genes are unlikely to increase breast cancer risk (2007)

Baynes, Caroline, Healey, Catherine S, Pooley, Karen A, Scollen, Serena, Luben, Robert N, Thompson, Deborah J, ...

Abstract Introduction Certain rare, familial mutations in the ATM , BRCA1 , BRCA2 , CHEK2 or TP53 genes increase susceptibility to breast cancer but it has not, until now, been clear whether common...

Common variation in EMSYand risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs (2005)

Benusiglio, Patrick R, Lesueur, Fabienne, Luccarini, Craig, McIntosh, Joan, Luben, Robert N, Smith, Paula, ...

Abstract Background EMSY could be involved in low-level susceptibility to breast and ovarian cancer. Gene amplification is seen in a proportion of breast and ovarian tumours and correlates with poor...

Common ERBB2polymorphisms and risk of breast cancer in a white British population: a case–control study (2005)

Benusiglio, Patrick R, Lesueur, Fabienne, Luccarini, Craig, Conroy, Donald M, Shah, Mitul, Easton, Douglas F, ...

Abstract Introduction About two-thirds of the excess familial risk associated with breast cancer is still unaccounted for and may be explained by multiple weakly predisposing alleles. A gene thought...

Introducing a new section to Breast Cancer Research: Endocrinology and hormone therapy (2003)

Craig Jordan, V, Ponder, Bruce AJ

Abstract Endocrine therapy is increasingly understood as the conceptual basis for the future treatment and prevention of breast cancer. Endocrine agents have considerably changed the approach to...

Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal (2003)

Daigo, Yataro, Takayama, Ichiro, Ponder, Bruce AJ, Caldas, Carlos, Ward, Sean M, Sanders, Kenton M, ...

Abstract Background We previously identified eight known and novel genes differentially expressed in the small intestines of wild type and W/W V mice, which have greatly reduced populations of the...

Differential gene expression in the murine gastric fundus lacking interstitial cells of Cajal (2003)

Daigo, Yataro, Takayama, Ichiro, Ponder, Bruce AJ, Caldas, Carlos, Ward, Sean M, Sanders, Kenton M, ...

Abstract Background The muscle layers of murine gastric fundus have no interstitial cells of Cajal at the level of the myenteric plexus and only possess intramuscular interstitial cells and this...

BRCA1 and BRCA2 mutations in a population-based study of male breast cancer (2001)

Basham, Victoria M, Lipscombe, Julian M, Ward, Joanna M, Gayther, Simon A, Ponder, Bruce AJ, Easton, Douglas F, ...

Abstract Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer (MBC) in the United Kingdom is not known, and the importance of these genes in the increased risk of...

Introducing a new section to Breast Cancer Research: Endocrinology and hormone therapy

Craig Jordan, V, Ponder, Bruce AJ

Endocrine therapy is increasingly understood as the conceptual basis for the future treatment and prevention of breast cancer. Endocrine agents have considerably changed the approach to targeted...

Introducing a new section to Breast Cancer Research: Endocrinology and hormone therapy

Craig Jordan, V, Ponder, Bruce AJ

Endocrine therapy is increasingly understood as the conceptual basis for the future treatment and prevention of breast cancer. Endocrine agents have considerably changed the approach to targeted...