Gulli, Marie-Pierre, Girard, Jean-Philippe, Zabetakis, Dan, Lapeyre, Bruno, Melese, Teri, Caizergues-Ferrer, Michele
Several nucleolar proteins, such as nucleolin, NOP1/flbrillarln, SSB1, NSR1 and GAR1 share a common glycine and arglnlne rich structural motif called the GAR domain. To identify novel nucleolar...
Girard, Jean-Philippe, Feliu, Jacgues, Caizergues-Ferrer, MichÈle, Lapeyre, Bruno
Flbrillarin is a nucleolar protein which is associated with small nucleolar RNAs, and is required for pre-rRNA processing. We have cloned and characterized the gene encoding flbrillarin in the...
Lapeyre, Bruno, Caizergues-Ferrer, Michèle, Bouche, Gérard, Amalric, François
Nucleoline (100 kDa) is the major nucleolar protein in exponentially growing cells that behaves like a nucleolar organizer protein and plays a key role in rDNA transcription and prerRNA processing....
Thesis (doctoral)--Faculté de médecine de Lyon, 1968.
Pintard, Lionel, Kressler, Dieter, Lapeyre, Bruno
We present here the characterization of SPB1, an essential yeast gene that is required for ribosome synthesis. A cold-sensitive allele for that gene (referred to here as spb1-1) had been previously...
Bonnerot, Claire, Boeck, Ronald, Lapeyre, Bruno
We report here the characterization of a bypass suppressor of pab1Δ which leads to a fourfold stabilization of the unstable MFA2 mRNA. Cloning of the wild-type gene for that suppressor reveals that...
Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant
Boeck, Ronald, Lapeyre, Bruno, Brown, Christine E., Sachs, Alan B.
mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8 (YJL124c) gene,...
Trm7p catalyses the formation of two 2′-O-methylriboses in yeast tRNA anticodon loop
Pintard, Lionel, Lecointe, François, Bujnicki, Janusz M., Bonnerot, Claire, Grosjean, Henri, Lapeyre, Bruno
The genome of Saccharomyces cerevisiae encodes three close homologues of the Escherichia coli 2′-O-rRNA methyltransferase FtsJ/RrmJ, designated Trm7p, Spb1p and Mrm2p. We present evidence that...
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase
Pintard, Lionel, Bujnicki, Janusz M., Lapeyre, Bruno, Bonnerot, Claire
Mitochondria of the yeast Saccharomyces cerevisiae assemble their ribosomes from ribosomal proteins, encoded by the nuclear genome (with one exception), and rRNAs of 15S and 21S, encoded by the...
Purushothaman, Suresh K., Bujnicki, Janusz M., Grosjean, Henri, Lapeyre, Bruno
N2-Monomethylguanosine-10 (m2G10) and N2,N2-dimethylguanosine-26 (m22G26) are the only two guanosine modifications that have been detected in tRNA from nearly all archaea and eukaryotes but not in...
Pintard, Lionel, Kressler, Dieter, Lapeyre, Bruno
We present here the characterization of SPB1, an essential yeast gene that is required for ribosome synthesis. A cold-sensitive allele for that gene (referred to here as spb1-1) had been previously...
Bonnerot, Claire, Boeck, Ronald, Lapeyre, Bruno
We report here the characterization of a bypass suppressor of pab1Δ which leads to a fourfold stabilization of the unstable MFA2 mRNA. Cloning of the wild-type gene for that suppressor reveals that...
Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant
Boeck, Ronald, Lapeyre, Bruno, Brown, Christine E., Sachs, Alan B.
mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8 (YJL124c) gene,...
Trm7p catalyses the formation of two 2′-O-methylriboses in yeast tRNA anticodon loop
Pintard, Lionel, Lecointe, François, Bujnicki, Janusz M., Bonnerot, Claire, Grosjean, Henri, Lapeyre, Bruno
The genome of Saccharomyces cerevisiae encodes three close homologues of the Escherichia coli 2′-O-rRNA methyltransferase FtsJ/RrmJ, designated Trm7p, Spb1p and Mrm2p. We present evidence that...
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase
Pintard, Lionel, Bujnicki, Janusz M., Lapeyre, Bruno, Bonnerot, Claire
Mitochondria of the yeast Saccharomyces cerevisiae assemble their ribosomes from ribosomal proteins, encoded by the nuclear genome (with one exception), and rRNAs of 15S and 21S, encoded by the...
Purushothaman, Suresh K., Bujnicki, Janusz M., Grosjean, Henri, Lapeyre, Bruno
N2-Monomethylguanosine-10 (m2G10) and N2,N2-dimethylguanosine-26 (m22G26) are the only two guanosine modifications that have been detected in tRNA from nearly all archaea and eukaryotes but not in...