Bryan Coburn

The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model. (2004)

Zaharik, Michelle L., Cullen, Vivian Li, Fung, Angela M., Libby, Stephen J., Kujat Choy, Sonya L., Coburn, Bryan, ...

Nramp1 is a transporter that pumps divalent cations from the vacuoles of phagocytic cells and is associated with the innate resistance of mice to diverse intracellular pathogens. We demonstrate that...

The Salmonella enterica Serovar Typhimurium Divalent Cation Transport Systems MntH and SitABCD Are Essential for Virulence in an Nramp1G169 Murine Typhoid Model

Zaharik, Michelle L., Cullen, Vivian Li, Fung, Angela M., Libby, Stephen J., Kujat Choy, Sonya L., Coburn, Bryan, ...

Nramp1 is a transporter that pumps divalent cations from the vacuoles of phagocytic cells and is associated with the innate resistance of mice to diverse intracellular pathogens. We demonstrate that...

Salmonella enterica Serovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis

Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett

Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...

The Salmonella enterica Serovar Typhimurium Divalent Cation Transport Systems MntH and SitABCD Are Essential for Virulence in an Nramp1G169 Murine Typhoid Model

Zaharik, Michelle L., Cullen, Vivian Li, Fung, Angela M., Libby, Stephen J., Kujat Choy, Sonya L., Coburn, Bryan, ...

Nramp1 is a transporter that pumps divalent cations from the vacuoles of phagocytic cells and is associated with the innate resistance of mice to diverse intracellular pathogens. We demonstrate that...

Salmonella enterica Serovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis

Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett

Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...

Salmonella enterica Serovar Senftenberg Human Clinical Isolates Lacking SPI-1▿

Hu, Qinghua, Coburn, Bryan, Deng, Wanyin, Li, Yuling, Shi, Xiaolu, Lan, Quanxue, ...

Nontyphoidal Salmonella species cause gastrointestinal disease worldwide. The prevailing theory of Salmonella enteropathogenesis is that bacterial invasion of the intestinal epithelium is essential...

Type III Secretion Systems and Disease

Coburn , Bryan, Sekirov, Inna, Finlay, B. Brett

Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-negative pathogens with a unique virulence mechanism enabling them to inject bacterial effector proteins directly...