Bryan Krastins

1 RESEARCH ARTICLE MapQuant: Open-source software for large-scale (2008)

Protein Quantification, Kyriacos C. Leptos, David A. Sarracino, Jacob D. Jaffe, Bryan Krastins, George M. Church

Whole-cell protein quantification using MS has proven to be a challenging task. Detection efficiency varies significantly from peptide to peptide, molecular identities are not evident a priori, and...

High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis (2007)

Gobezie, Reuben, Kho, Alvin, Krastins, Bryan, Sarracino, David A, Thornhill, Thomas S, Chase, Michael, ...

Abstract The development of increasingly high-throughput and sensitive mass spectroscopy-based proteomic techniques provides new opportunities to examine the physiology and pathophysiology of many...

High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis. (2007)

Gobezie, Reuben, Kho, Alvin, Krastins, Bryan, Sarracino, David A, Thornhill, Thomas S, Chase, Michael, ...

The development of increasingly high-throughput and sensitive mass spectroscopy-based proteomic techniques provides new opportunities to examine the physiology and pathophysiology of many biologic...

Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction (2006)

Robertson, Nahid G., Huygen, Patrick L.M., Ikezono, Tetsuo, Krastins, Bryan, Kremer, Hannie, ...

Seven missense mutations and one in-frame deletion mutation have been reported in the coagulation factor C homology (COCH) gene, causing the adult-onset, progressive sensorineural hearing loss and...

Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction (2006)

Robertson, Nahid G., Huygen, Patrick L.M., Ikezono, Tetsuo, Krastins, Bryan, Kremer, Hannie, ...

Seven missense mutations and one in-frame deletion mutation have been reported in the COCH (coagulation factor Chomology) gene, causing the adult-onset, progressive sensorineural hearing loss and...

Use of In Vivo-Induced Antigen Technology for Identification of Escherichia coli O157:H7 Proteins Expressed during Human Infection

John, Manohar, Kudva, Indira T., Griffin, Robert W., Dodson, Allen W., McManus, Bethany, Krastins, Bryan, ...

Using in vivo-induced antigen technology (IVIAT), a modified immunoscreening technique that circumvents the need for animal models, we directly identified immunogenic Escherichia coli O157:H7 (O157)...

Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system

Pukatzki, Stefan, Ma, Amy T., Sturtevant, Derek, Krastins, Bryan, Sarracino, David, Nelson, William C., ...

The bacterium Vibrio cholerae, like other human pathogens that reside in environmental reservoirs, survives predation by unicellular eukaryotes. Strains of the O1 and O139 serogroups cause cholera,...

Use of In Vivo-Induced Antigen Technology for Identification of Escherichia coli O157:H7 Proteins Expressed during Human Infection

John, Manohar, Kudva, Indira T., Griffin, Robert W., Dodson, Allen W., McManus, Bethany, Krastins, Bryan, ...

Using in vivo-induced antigen technology (IVIAT), a modified immunoscreening technique that circumvents the need for animal models, we directly identified immunogenic Escherichia coli O157:H7 (O157)...

Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system

Pukatzki, Stefan, Ma, Amy T., Sturtevant, Derek, Krastins, Bryan, Sarracino, David, Nelson, William C., ...

The bacterium Vibrio cholerae, like other human pathogens that reside in environmental reservoirs, survives predation by unicellular eukaryotes. Strains of the O1 and O139 serogroups cause cholera,...

High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis

Gobezie, Reuben, Kho, Alvin, Krastins, Bryan, Sarracino, David A, Thornhill, Thomas S, Chase, Michael, ...

The development of increasingly high-throughput and sensitive mass spectroscopy-based proteomic techniques provides new opportunities to examine the physiology and pathophysiology of many biologic...

Proteomic Analysis of Vibrio cholerae in Human Stool▿ †

LaRocque, Regina C., Krastins, Bryan, Harris, Jason B., Lebrun, Lauren M., Parker, Kenneth C., Chase, Michael, ...

An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V....

Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling

Qureshi, Amir H., Chaoji, Vineet, Maiguel, Dony, Faridi, Mohd Hafeez, Barth, Constantinos J., Salem, Saeed M., ...

During atherogenesis and vascular inflammation quiescent platelets are activated to increase the surface expression and ligand affinity of the integrin αIIbβ3 via inside-out signaling. Diverse...