Bryan R. Hewlett

Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts

Sime, Patricia J., Marr, Robert A., Gauldie, David, Xing, Zhou, Hewlett, Bryan R., Graham, Frank L., ...

Tumor necrosis factor-α is up-regulated in a variety of different human immune-inflammatory and fibrotic pulmonary pathologies. However, its precise role in these pathologies and, in particular, the...

Gastrointestinal Stromal Tumors May Originate from a Subset of CD34-Positive Interstitial Cells of Cajal

Robinson, Tim L., Sircar, Kanishka, Hewlett, Bryan R., Chorneyko, Katherine, Riddell, Robert H., Huizinga, Jan D.

Most gastrointestinal stromal tumors (GISTs), a subgroup of mesenchymal neoplasms of the gut wall, express both Kit (CD117) and CD34 proteins. It has been suggested that GISTs originate from or...