Cátia Moutinho

BRAF, KRASand PIK3CAmutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis? (2008)

Velho, Sérgia, Moutinho, Cátia, Cirnes, Luís, Albuquerque, Cristina, Hamelin, Richard, Schmitt, Fernando, ...

Abstract Background BRAF , KRAS and PIK3CA mutations are frequently found in sporadic colorectal cancer (CRC). In contrast to KRAS and PIK3CA mutations, BRAF mutations are associated with tumours...

Epidermal growth factor receptor structural alterations in gastric cancer (2008)

Moutinho, Cátia, Mateus, Ana R, Milanezi, Fernanda, Carneiro, Fátima, Seruca, Raquel, Suriano, Gianpaolo

Abstract Background EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well...

DNA copy number profiles of gastric cancer precursor lesions (2007)

Buffart, Tineke E, Carvalho, Beatriz, Mons, Thomas, Reis, Rui M, Moutinho, Cátia, Silva, Paula, ...

Abstract Background Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still...

DNA copy number profiles of gastric cancer precursor lesions (2007)

Buffart, Tineke, Carvalho, Beatriz, Mons, Thomas, Reis, R. M., Moutinho, Cátia, Silva, Paula, ...

Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still obscure. In the present...