C. Dean

Publication List Details

Period

1036 - 2008

Number

35

Co-Authors

DL POLY: A Macromolecular Simulation Package (2007)

Smith Daresbury, W. Smith, Daresbury Laboratory, C. Dean

systems and a variety of ensembles and boundary conditions. Bond forces (including valence and dihedral angles) will also be incorporated. Nonbonded forces will be handled by the Replicated Data...

Title: An Evaluation Method for COTS Software Products (2007)

C. Dean

Abstract: Employing Commercial Off-the-Shelf (COTS) software products as components in large-scale long-lived systems has been proposed as a way to reduce both implementation and operating cost for...

Title: System Implementation Using Commercial Off-The-Shelf Software (2007)

C Dean, Cd Dr, Mark R Vigder

Abstract: In an attempt to reduce cost and delivery time of software systems Commercial Off-The-Shelf (COTS) software components are being used in increasing numbers. The source code for these...

Nonembeddable Factors of the Enveloping Algebras of Semisimple Lie Algebras (2006)

Dean, C.

It is shown that the enveloping algebra of every (finite dimensional, complex) semisimple Lie algebra has a factor ring which cannot be embedded in any Artinian ring. The proof helps to clarify the...

LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC (2006)

Mylne, J. S., Barrett, L., Tessadori, F., Mesnage, S., Johnson, L., Bernatavichute, Y. V., ...

Vernalization is the acceleration of flowering by prolonged cold that aligns the onset of reproductive development with spring conditions. A key step of vernalization in Arabidopsis is the epigenetic...

Additional targets of the Arabidopsis autonomous pathway members, FCA and FY (2006)

Marquardt, S., Boss, P. K., Hadfield, J., Dean, C.

A central player in the Arabidopsis floral transition is the floral repressor FLC, the MADS-box transcriptional regulator that inhibits the activity of genes required to switch the meristem from...

Additional targets of the Arabidopsis autonomous pathway members, FCA and FY (2006)

Marquardt, S, Boss, PK, Hadfield, J, Dean, C

A central player in the Arabidopsis floral transition is the floral repressor FLC, the MADS-box transcriptional regulator that inhibits the activity of genes required to switch the meristem from...

Additional targets of the Arabidopsis autonomous pathway members, FCA and FY (2006)

Marquardt, S., Boss, P. K., Hadfield, J., Dean, C.

A central player in the Arabidopsis floral transition is the floral repressor FLC, the MADS-box transcriptional regulator that inhibits the activity of genes required to switch the meristem from...

Vernalization requires epigenetic silencing of FLC by histone methylation (2004)

Bastow, R., Mylne, J. S., Lister, C., Lippman, Z., Martienssen, R. A., Dean, C.

To ensure flowering in favourable conditions, many plants flower only after an extended period of cold, namely winter. In Arabidopsis, the acceleration of flowering by prolonged cold, a process...

Epigenetic regulation in the control of flowering (2004)

Mylne, J. S., Greb, T., Lister, C., Dean, C.

The timing of flowering has significant consequencesfor the reproductive success of plants. Plants need togauge when both environmental and endogenous cues areoptimal before undergoing the switch...

Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control (2002)

Levy, Y. Y., Mesnage, S., Mylne, J. S., Gendall, A. R., Dean, C.

Arabidopsis VRN genes mediate vernalization, the process by which a long period of cold induces a mitotically stable state that leads to accelerated flowering during later development. VRN1 encodes a...

Integrated cytogenetic map of chromosome arm 4S of A. thaliana : structural organization of heterochromatic knob and centromere region (2000)

Fransz, P.F., Armstrong, S., Parnell, L.D., Dean, C., ...

We have constructed an integrated cytogenetic map of chromosome arm 4S of Arabidopsis thaliana. The map shows the detailed positions of various multicopy and unique sequences relative to euchromatin...

PFGE-resolved RFLP analysis and long range restriction mapping of the DNA of Arabidopsis thaliana using whole YAC clones as probes (1992)

Bancroft, I., Westphal, L., Schmidt, R., Dean, C.

The cleavage patterns of 23 rare-cutting restriction endonucleases (rcREs) on high molecular weight DNA, isolated from leaves of Arabidopsis thaliana (Arabidopsis), have been analysed using pulsed...

Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction.

Modjtahedi, H., Eccles, S., Box, G., Styles, J., Dean, C.

Athymic mice bearing xenografts of human tumours that overexpress the receptor (EGFR) for EGF and TGF alpha have been used to evaluate the therapeutic potential of three new rat monoclonal antibodies...

Radioimmunolocalisation in breast cancer using the gene product of c-erbB2 as the target antigen.

Allan, S. M., Dean, C., Fernando, I., Eccles, S., Styles, J., McCready, V. R., ...

Lymph node status is still the single most important prognostic factor in breast cancer. Axillary surgery remains the only reliable means of providing this information. This pilot study evaluates...

The effect of circulating antigen and radiolabel stability on the biodistribution of an indium labelled antibody.

Davidson, B. R., Babich, J., Young, H., Waddington, W., Clarke, G., Short, M., ...

This study has investigated two of the main problems with radiolabelled antibody imaging, the formation of circulating immune complexes (I.C.) and the non specific binding of radiolabel to the...

Phase I trial and tumour localisation of the anti-EGFR monoclonal antibody ICR62 in head and neck or lung cancer.

Modjtahedi, H., Hickish, T., Nicolson, M., Moore, J., Styles, J., Eccles, S., ...

The purpose of this study was to determine the effect of the first rat monoclonal antibody (MAb ICR62) to the epidermal growth factor receptor (EGFR) in a phase I clinical trial in patients with...