To better understand the effects of ambient relative humidity (RH) on physiological variables and the implications of RH-correcting evaporative water loss (EWL) data for marsupials, we examined the...
Dormancy or torpor is a widely-recognized behavioral and physiological state of both animals and plants that generally indicates inactivity and reduced metabolic rate. It can involve very different...
Dormancy or torpor is a widely-recognized behavioral and physiological state of both animals and plants that generally indicates inactivity and reduced metabolic rate. It can involve very different...
To better understand the effects of ambient relative humidity (RH) on physiological variables and the implications of RH-correcting evaporative water loss (EWL) data for marsupials, we examined the...
Tachtsidis, I., Tisdall, M., Leung, T.S., Cooper, C.E., Delpy, D.T., Smith, M., ...
We have previously used a continuous four wavelength near infrared spectrometer to measure changes in the cerebral concentrations of oxy- (Δ[HbO2] and deoxy- haemoglobin (Δ[HHb]) during head-up...
Nitrosyl heme production compared in endotoxemic and hemorrhagic shock (2005)
Davies, N.A., Brealey, D.A., Stidwill, R., Singer, M., Svistunenko, D.A., Cooper, C.E.
We compared nitric oxide production and nitrosyl hemoglobin steady state concentrations during the early phases of endotoxemic and hemorrhagic shock of equivalent severity. Sprague–Dawley rats were...
Withers, P.C, Cooper, C.E., Buttemer, W. A.
Small desert birds are typically diurnal and highly mobile (hence conspicuous) whereas small non-volant mammals are generally nocturnal and less mobile (hence inconspicuous). Birds are more mobile...
Association between mitochondrial dysfunction and severity and outcome of septic shock (2002)
Brealey, D., Brand, M., Hargreaves, I., Heales, S., Land, J., Smolenski, R., ...
Summary: Background: Sepsis-induced multiple organ failure is the major cause of mortality and morbidity in critically ill patients. However, the precise mechanisms by which this dysfunction is...
Association between mitochondrial dysfunction and severity and outcome of septic shock (2002)
Brealey, D., Brand, M., Hargreaves, I., Heales, S., Land, J., Smolenski, R., ...
Background: Sepsis-induced multiple organ failure is the major cause of mortality and morbidity in critically ill patients. However, the precise mechanisms by which this dysfunction is caused remain...
Thesis (M.P.A.)--University of Stellenbosch, 1993.
Tan, H M, Joannou, C L, Cooper, C E, Butler, C S, Cammack, R, Mason, J R
The benzene dioxygenase from Pseudomonas putida ML2 is a multicomponent complex comprising a flavoprotein reductase, a ferredoxin, and a terminal iron-sulfur protein (ISP). The catalytic activity of...
Wrigglesworth, J M, Cooper, C E, Sharpe, M A, Nicholls, P
1. The flux pathways for H+ and K+ movements into and out of proteoliposomes incorporating cytochrome c oxidase have been investigated as a function of the electrical and geometrical properties of...
Spectroscopic studies on an oxygen-binding haemoglobin-like flavohaemoprotein from Escherichia coli.
Ioannidis, N, Cooper, C E, Poole, R K
The Escherichia coli haemoglobin-like flavohaemoprotein (Hmp) has been purified to near homogeneity using two chromatographic steps. The prosthetic groups are identified as FAD and protohaem IX....
Cooper, C E, Markus, M, Seetulsingh, S P, Wrigglesworth, J M
1. Psychosine (beta-galactosylsphingosine) is the toxic agent in Krabbe's disease (globoid cells leukodystrophy). It inhibits purified bovine heart mitochondrial cytochrome c oxidase; there is a...
Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step?
Control analysis is used to analyse and quantify the concept of a rate-limiting step within an enzyme. The extent to which each rate constant within the enzyme limits the steady-state rate of the...
The extent to which a rate constant or step within an enzyme mechanism limits the net enzyme rate in a particular condition can be quantified as a flux control coefficient. We derive here a number of...
The aerobic reactions of nitric oxide with cytochrome c were analysed. Nitric oxide (NO) reacts with ferrocytochrome c at a rate of 200 M-1 s-1 to form ferricytochrome c and nitroxyl anion (NO-)....
Cooper, C E, Delpy, D T, Nemoto, E M
Near-infrared spectroscopy was used to determine the effect of changes in the rate of oxygen delivery to the adult rat brain on the absolute concentrations of oxyhaemoglobin, deoxyhaemoglobin and the...
Svistunenko, D A, Sharpe, M A, Nicholls, P, Blenkinsop, C, Davies, N A, Dunne, J, ...
The paramagnetic species in human metHb and horse metmyoglobin (metMb) have been studied at low temperature using EPR spectroscopy. The high-spin (HS) haem signal in aquometMb has a greater rhombic...
Nitric oxide synthases: structure, function and inhibition.
Alderton, W K, Cooper, C E, Knowles, R G
This review concentrates on advances in nitric oxide synthase (NOS) structure, function and inhibition made in the last seven years, during which time substantial advances have been made in our...
Tan, H M, Joannou, C L, Cooper, C E, Butler, C S, Cammack, R, Mason, J R
The benzene dioxygenase from Pseudomonas putida ML2 is a multicomponent complex comprising a flavoprotein reductase, a ferredoxin, and a terminal iron-sulfur protein (ISP). The catalytic activity of...
Wrigglesworth, J M, Cooper, C E, Sharpe, M A, Nicholls, P
1. The flux pathways for H+ and K+ movements into and out of proteoliposomes incorporating cytochrome c oxidase have been investigated as a function of the electrical and geometrical properties of...
Spectroscopic studies on an oxygen-binding haemoglobin-like flavohaemoprotein from Escherichia coli.
Ioannidis, N, Cooper, C E, Poole, R K
The Escherichia coli haemoglobin-like flavohaemoprotein (Hmp) has been purified to near homogeneity using two chromatographic steps. The prosthetic groups are identified as FAD and protohaem IX....
Cooper, C E, Markus, M, Seetulsingh, S P, Wrigglesworth, J M
1. Psychosine (beta-galactosylsphingosine) is the toxic agent in Krabbe's disease (globoid cells leukodystrophy). It inhibits purified bovine heart mitochondrial cytochrome c oxidase; there is a...
Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step?
Control analysis is used to analyse and quantify the concept of a rate-limiting step within an enzyme. The extent to which each rate constant within the enzyme limits the steady-state rate of the...
The extent to which a rate constant or step within an enzyme mechanism limits the net enzyme rate in a particular condition can be quantified as a flux control coefficient. We derive here a number of...
The aerobic reactions of nitric oxide with cytochrome c were analysed. Nitric oxide (NO) reacts with ferrocytochrome c at a rate of 200 M-1 s-1 to form ferricytochrome c and nitroxyl anion (NO-)....
Cooper, C E, Delpy, D T, Nemoto, E M
Near-infrared spectroscopy was used to determine the effect of changes in the rate of oxygen delivery to the adult rat brain on the absolute concentrations of oxyhaemoglobin, deoxyhaemoglobin and the...
Svistunenko, D A, Sharpe, M A, Nicholls, P, Blenkinsop, C, Davies, N A, Dunne, J, ...
The paramagnetic species in human metHb and horse metmyoglobin (metMb) have been studied at low temperature using EPR spectroscopy. The high-spin (HS) haem signal in aquometMb has a greater rhombic...
Nitric oxide synthases: structure, function and inhibition.
Alderton, W K, Cooper, C E, Knowles, R G
This review concentrates on advances in nitric oxide synthase (NOS) structure, function and inhibition made in the last seven years, during which time substantial advances have been made in our...
Measurement of cytochrome oxidase and mitochondrial energetics by near-infrared spectroscopy.
Cytochrome oxidase is the terminal electron acceptor of the mitochondrial respiratory chain. It is responsible for the vast majority of oxygen consumption in the body and essential for the efficient...
Studio Photo of Young Women in Ypsilanti
B/W; Poor - mounted on board, spotted; 4x5.5; .TIF; Photo Files; 600dpi
Studio Photo of Young Women in Ypsilanti
B/W; Poor - mounted on board, spotted; 4x5.5; .TIF; Photo Files; 600dpi