Increase in cerebral aerobic metabolism by normobaric hyperoxia after traumatic brain injury (2008)
Tisdall, M.M., Tachtsidis, I., Leung, T.S., Elwell, C.E., Smith, M.
OBJECT: Traumatic brain injury (TBI) is associated with depressed aerobic metabolism and mitochondrial dysfunction. Normobaric hyperoxia (NBH) has been suggested as a treatment for TBI, but studies...
Tisdall, M.M., Tachtsidis, I., Leung, T.S., Elwell, C.E., Smith, M.
The near infrared cytochrome c oxidase (CCO) signal has potential as a clinical marker of changes in mitochondrial oxygen utilization. We examine the CCO signal response to reduced oxygen delivery in...
Tachtsidis, I., Tisdall, M., Leung, T.S., Cooper, C.E., Delpy, D.T., Smith, M., ...
We have previously used a continuous four wavelength near infrared spectrometer to measure changes in the cerebral concentrations of oxy- (Δ[HbO2] and deoxy- haemoglobin (Δ[HHb]) during head-up...
Koh, P.H., Glaser, D.E., Flandin, G., Butterworth, B., Maki, A., Delpy, D., ...
Optical topography (OT) relies on the near infrared spectroscopy (NIRS) technique to provide a spatial map of the functional brain activity non-invasively. It has advantages over conventional fMRI in...
Leung, T.S., Tachtsidis, I., Smith, M., Delpy, D.T., Elwell, C.E.
A hybrid differential and spatially resolved spectroscopy (SRS) technique has been developed to measure absolute absorption coefficient (μa), reduced scattering coefficient (μ's) and cerebral blood...
Regional haemodynamic responses to visual stimulation in awake infants (1998)
Meek, J.H., Firbank, M., Elwell, C.E., Atkinson, J., Braddick, O., Wyatt, J.
This study presents the first measurements using near infrared spectroscopy of changes in regional hemodynamics as a response to a visual stimulus in awake infants. Ten infants aged 3 d to 14 wk...