Varani, J, Perone, P, Griffiths, C E, Inman, D R, Fligiel, S E, Voorhees, J J
Adult human skin from a sun-protected site (hip) and from a sun-exposed site (forearm) was maintained in organ culture for 12 d in the presence of a serum-free, growth factor-free basal medium....
Mahoney, S E, Duvic, M, Nickoloff, B J, Minshall, M, Smith, L C, Griffiths, C E, ...
Persons with HIV infection sometimes develop aggressive psoriasis or Kaposi's sarcoma (KS) not usually seen in other immunosuppressed patients. However, a specific and direct pathophysiological role...
Duell, E A, Aström, A, Griffiths, C E, Chambon, P, Voorhees, J J
Metabolism of retinoic acid to a less active metabolite, 4-hydroxyretinoic acid, occurs via cytochrome P-450 isozyme(s). Effect of a pharmacological dose of retinoic acid on the level of retinoic...
Dermatological conditions in HIV infection.
Walker, M M, Griffiths, C E, Weber, J, Leonard, J N, Forster, S M, Powles, A V, ...
Clearance of psoriasis with low dose cyclosporin.
Griffiths, C E, Powles, A V, Leonard, J N, Fry, L, Baker, B S, Valdimarsson, H
Varani, J, Perone, P, Griffiths, C E, Inman, D R, Fligiel, S E, Voorhees, J J
Adult human skin from a sun-protected site (hip) and from a sun-exposed site (forearm) was maintained in organ culture for 12 d in the presence of a serum-free, growth factor-free basal medium....
Mahoney, S E, Duvic, M, Nickoloff, B J, Minshall, M, Smith, L C, Griffiths, C E, ...
Persons with HIV infection sometimes develop aggressive psoriasis or Kaposi's sarcoma (KS) not usually seen in other immunosuppressed patients. However, a specific and direct pathophysiological role...
Duell, E A, Aström, A, Griffiths, C E, Chambon, P, Voorhees, J J
Metabolism of retinoic acid to a less active metabolite, 4-hydroxyretinoic acid, occurs via cytochrome P-450 isozyme(s). Effect of a pharmacological dose of retinoic acid on the level of retinoic...
Dermatological conditions in HIV infection.
Walker, M M, Griffiths, C E, Weber, J, Leonard, J N, Forster, S M, Powles, A V, ...
Clearance of psoriasis with low dose cyclosporin.
Griffiths, C E, Powles, A V, Leonard, J N, Fry, L, Baker, B S, Valdimarsson, H
Nickoloff, B. J., Griffiths, C. E.
The Ki-67 antibody, which reacts with nuclei of actively proliferating cells, was used in an immunohistochemical study to determine if there was any difference between T cells located in the...
Nickoloff, B. J., Griffiths, C. E.
Kaposi's sarcoma is a neoplasm that develops as multifocal lesions, often involving the skin, characterized by a complex histologic picture including numerous vascular spaces, perivascular and...
Griffiths, C. E., Nickoloff, B. J.
The ability of small molecules such as urushiol, present as a wax on the poison ivy leaf surface, to cause allergic contact dermatitis (rhus dermatitis) has fascinated immunologists for decades....
Sachs, J A, Awad, J, McCloskey, D, Navarrete, C, Festenstein, H, Elliot, E, ...
Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac...
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.
Nickoloff, B. J., Karabin, G. D., Barker, J. N., Griffiths, C. E., Sarma, V., Mitra, R. S., ...
The importance of immunologic mechanisms in psoriasis has been deduced from the ability of immunosuppressive therapies to ameliorate this common and chronic skin disease. Certainly the histology of...
Effects of all-trans retinoic acid and Ca++ on human skin in organ culture.
Varani, J., Fligiel, S. E., Schuger, L., Perone, P., Inman, D., Griffiths, C. E., ...
In this study, we have established an organ culture model of human skin and examined the effects of both all-trans retinoic acid (RA) and extracellular Ca++ on the epidermal and dermal components of...
Preferential activation of CD4 T lymphocytes in the lamina propria of gluten-sensitive enteropathy.
Griffiths, C E, Barrison, I G, Leonard, J N, Caun, K, Valdimarsson, H, Fry, L
The distribution and activation of T-lymphocyte subsets in the small intestinal mucosa of coeliac disease and dermatitis herpetiformis subjects on a normal diet has been studied and compared to...
Baker, B S, Swain, A F, Griffiths, C E, Leonard, J N, Fry, L, Valdimarsson, H
The numbers and HLA-DR expression of T cell subsets and dendritic cells in chronic psoriatic plaques were compared to previously reported findings in spontaneously resolving guttate lesions, and the...