C. F. Schmidt

Publication List Details

Period

1997 - 2008

Number

46

Co-Authors

Effective temperatures from the fluctuation-dissipation measurements in soft glassy materials (2008)

Jabbari-Farouji, S., Mizuno, D., Derks, D., Wegdam, G. H., MacKintosh, F. C., Schmidt, C. F., ...

We have investigated the validity of the fluctuation-dissipation theorem (FDT) and the applicability of the concept of effective temperature in a number of non-equilibrium soft glassy materials....

Short-time inertial response of viscoelastic fluids measured with Brownian motion and with active probes (2008)

Atakhorrami, M., Mizuno, D., Koenderink, G. H., Liverpool, T. B., MacKintosh, F. C., Schmidt, C. F.

We have directly observed short-time stress propagation in viscoelastic fluids using two optically trapped particles and a fast interferometric particle-tracking technique. We have done this both by...

Microtubule-Driven Multimerization Recruits ase1p onto Overlapping Microtubules (2008)

Kapitein, L.C., Janson, M.E., Hoogenraad, C.C., Schmidt, C.F., Peterman, E.J.G.

Microtubule (MT) crosslinking proteins of the ase1p/PRC1/Map65 family play a major role in the construction of MT networks such as the mitotic spindle. Most homologs in this family have been shown to...

High-bandwidth viscoelastic properties of aging colloidal glasses and gels (2007)

Jabbari-Farouji, S., Atakhorram, M., Mizuno, D., Eiser, E., Wegdam, G. H., MacKintosh, F. C., ...

We report measurements of the frequency-dependent shear moduli of aging colloidal systems that evolve from a purely low-viscosity liquid to a predominantly elastic glass or gel. Using microrheology,...

Instability of Myelin Tubes under Dehydration: deswelling of layered cylindrical structures (2001)

Schmidt, C. F., Olmsted, P. D., MacKintosh, F. C.

We report experimental observations of an undulational instability of myelin figures. Motivated by this, we examine theoretically the deformation and possible instability of concentric, cylindrical,...

Determining Microscopic Viscoelasticity in Flexible and (1999)

B. Schnurr, F. Gittes, F. C. Mackintosh, C. F. Schmidt

We have developed a new technique to measure viscoelasticity in soft materials such as entangled polymer solutions, by monitoring thermal fluctuations of embedded probe particles using laser...

ECONOMICS OF SAFETY IN CIVIL AVIATION (PLANNING STUDY). (1998)

Lederer,J., Miller,C. O., Schmidt,C. F.

Information is developed to establish a program for the prudent management of resources allocated to safety. The study lists and defines the variables that constitute: (1) The monetary investment in...

Thermal noise limitations on micromechanical experiments (1998)

Schmidt, C. F., Gittes, Frederick

Thermal motions of microscopic probes limit the possibilities of experiments that are designed to resolve single-macromolecule dynamics in aqueous conditions. We investigate theoretical strategies...

Microscopic Viscoelasticity: Shear Moduli of Soft Materials Determined from Thermal Fluctuations (1997)

Gittes, F., Schnurr, B., Olmsted, P. D., MacKintosh, F. C., Schmidt, C. F.

We describe a high-resolution, high-bandwidth technique for determining the local viscoelasticity of soft materials such as polymer gels. Loss and storage shear moduli are determined from the power...

Determining Microscopic Viscoelasticity in Flexible and Semiflexible Polymer Networks from Thermal Fluctuations (1997)

Schnurr, B., Gittes, F., MacKintosh, F. C., Schmidt, C. F.

We have developed a new technique to measure viscoelasticity in soft materials such as polymer solutions, by monitoring thermal fluctuations of embedded probe particles using laser interferometry in...

Utilization of an Escherichia coli mutant for carbon-13 enrichment of tRNA for NMR studies.

Agris, P F, Fujiwara, F G, Schmidt, C F, Loeppky, R N

The enrichment of tRNA at specific sites with carbon-13 has been accomplished in vivo using a mutant of Escherichia coli. A relaxed strain of E. coli auxotrophic for methionine was grown in a...

Enrichment, Isolation, and Cultural Characteristics of Marine Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F., Boltz, J. K.

Terrestrial strains of Clostridium botulinum type C, designated 468 and 571, were used to screen various media for growth and sporulation at 30 C. Of the various formulations tested, only egg meat...

Minimal Growth Temperature, Sodium Chloride Tolerance, pH Sensitivity, and Toxin Production of Marine and Terrestrial Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F., Boltz, J. K.

Minimal growth temperatures of four marine and two terrestrial strains of Clostridium botulinum type C were determined in a laboratory culture medium, fortified egg meat medium (FEM), and in ground...

Heat Resistance of Spores of Marine and Terrestrial Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F.

Resistance to heat of spores of marine and terrestrial strains of Clostridium botulinum type C in 0.067 m phosphate buffer (pH 7.0) was determined. The marine strains were 6812, 6813, 6814, and 6816;...

Bacteriophage capsids: Tough nanoshells with complex elastic properties

Ivanovska, I. L., De Pablo, P. J., Ibarra, B., Sgalari, G., MacKintosh, F. C., Carrascosa, J. L., ...

The shell of bacteriophages protects the viral DNA during host-to-host transfer and serves as a high-pressure container storing energy for DNA injection into a host bacterium. Here, we probe the...

Effect of Sodium Chloride and pH on the Outgrowth of Spores of Type E Clostridium botulinum at Optimal and Suboptimal Temperatures1

Segner, W. P., Schmidt, C. F., Boltz, J. K.

The sodium chloride inhibition of spore outgrowth of four strains of type E Clostridium bolulinum was determined in a Trypticase-peptone-glucose (TPG) medium. At 16, 21, and 30 C, spores of three...

Nonspecific Toxicities in the Mouse Assay Test for Botulinum Toxin1

Segner, W. P., Schmidt, C. F.

In inoculated pack experiments on Clostridium botulinum type E, unirradiated and 0.1-Mrad irradiated haddock fillets often gave nonspecific toxicities by the mouse assay test for botulinum toxin....

Protein tracking and detection of protein motion using atomic force microscopy.

Thomson, N H, Fritz, M, Radmacher, M, Cleveland, J P, Schmidt, C F, Hansma, P K

Height fluctuations over three different proteins, immunoglobulin G, urease, and microtubules, have been measured using an atomic force microscope (AFM) operating in fluid tapping mode. This was...

Conformation and elasticity of the isolated red blood cell membrane skeleton.

Svoboda, K, Schmidt, C F, Branton, D, Block, S M

We studied the structure and elasticity of membrane skeletons from human red blood cells (RBCs) during and after extraction of RBC ghosts with nonionic detergent. Optical tweezers were used to...

Multilayer adsorption of lysozyme on a hydrophobic substrate.

Schmidt, C F, Zimmermann, R M, Gaub, H E

Macromolecular adsorption is known to occur as a complex process, often in a series of steps. Several models are discussed in the literature which describe the microscopic structure of the adsorbate....

Two-dimensional tracking of ncd motility by back focal plane interferometry.

Allersma, M W, Gittes, F, DeCastro, M J, Stewart, R J, Schmidt, C F

A technique for detecting the displacement of micron-sized optically trapped probes using far-field interference is introduced, theoretically explained, and used to study the motility of the ncd...

Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength

Michel, J. P., Ivanovska, I. L., Gibbons, M. M., Klug, W. S., Knobler, C. M., Wuite, G. J. L., ...

The elastic properties of capsids of the cowpea chlorotic mottle virus have been examined at pH 4.8 by nanoindentation measurements with an atomic force microscope. Studies have been carried out on...

Utilization of an Escherichia coli mutant for carbon-13 enrichment of tRNA for NMR studies.

Agris, P F, Fujiwara, F G, Schmidt, C F, Loeppky, R N

The enrichment of tRNA at specific sites with carbon-13 has been accomplished in vivo using a mutant of Escherichia coli. A relaxed strain of E. coli auxotrophic for methionine was grown in a...

Enrichment, Isolation, and Cultural Characteristics of Marine Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F., Boltz, J. K.

Terrestrial strains of Clostridium botulinum type C, designated 468 and 571, were used to screen various media for growth and sporulation at 30 C. Of the various formulations tested, only egg meat...

Minimal Growth Temperature, Sodium Chloride Tolerance, pH Sensitivity, and Toxin Production of Marine and Terrestrial Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F., Boltz, J. K.

Minimal growth temperatures of four marine and two terrestrial strains of Clostridium botulinum type C were determined in a laboratory culture medium, fortified egg meat medium (FEM), and in ground...

Heat Resistance of Spores of Marine and Terrestrial Strains of Clostridium botulinum Type C

Segner, W. P., Schmidt, C. F.

Resistance to heat of spores of marine and terrestrial strains of Clostridium botulinum type C in 0.067 m phosphate buffer (pH 7.0) was determined. The marine strains were 6812, 6813, 6814, and 6816;...

Bacteriophage capsids: Tough nanoshells with complex elastic properties

Ivanovska, I. L., De Pablo, P. J., Ibarra, B., Sgalari, G., MacKintosh, F. C., Carrascosa, J. L., ...

The shell of bacteriophages protects the viral DNA during host-to-host transfer and serves as a high-pressure container storing energy for DNA injection into a host bacterium. Here, we probe the...

Effect of Sodium Chloride and pH on the Outgrowth of Spores of Type E Clostridium botulinum at Optimal and Suboptimal Temperatures1

Segner, W. P., Schmidt, C. F., Boltz, J. K.

The sodium chloride inhibition of spore outgrowth of four strains of type E Clostridium bolulinum was determined in a Trypticase-peptone-glucose (TPG) medium. At 16, 21, and 30 C, spores of three...

Nonspecific Toxicities in the Mouse Assay Test for Botulinum Toxin1

Segner, W. P., Schmidt, C. F.

In inoculated pack experiments on Clostridium botulinum type E, unirradiated and 0.1-Mrad irradiated haddock fillets often gave nonspecific toxicities by the mouse assay test for botulinum toxin....

Protein tracking and detection of protein motion using atomic force microscopy.

Thomson, N H, Fritz, M, Radmacher, M, Cleveland, J P, Schmidt, C F, Hansma, P K

Height fluctuations over three different proteins, immunoglobulin G, urease, and microtubules, have been measured using an atomic force microscope (AFM) operating in fluid tapping mode. This was...

Conformation and elasticity of the isolated red blood cell membrane skeleton.

Svoboda, K, Schmidt, C F, Branton, D, Block, S M

We studied the structure and elasticity of membrane skeletons from human red blood cells (RBCs) during and after extraction of RBC ghosts with nonionic detergent. Optical tweezers were used to...

Multilayer adsorption of lysozyme on a hydrophobic substrate.

Schmidt, C F, Zimmermann, R M, Gaub, H E

Macromolecular adsorption is known to occur as a complex process, often in a series of steps. Several models are discussed in the literature which describe the microscopic structure of the adsorbate....

Two-dimensional tracking of ncd motility by back focal plane interferometry.

Allersma, M W, Gittes, F, DeCastro, M J, Stewart, R J, Schmidt, C F

A technique for detecting the displacement of micron-sized optically trapped probes using far-field interference is introduced, theoretically explained, and used to study the motility of the ncd...

Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength

Michel, J. P., Ivanovska, I. L., Gibbons, M. M., Klug, W. S., Knobler, C. M., Wuite, G. J. L., ...

The elastic properties of capsids of the cowpea chlorotic mottle virus have been examined at pH 4.8 by nanoindentation measurements with an atomic force microscope. Studies have been carried out on...