Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein.
Knauer, M F, Soreghan, B, Burdick, D, Kosmoski, J, Glabe, C G
The A4 or beta protein is a peptide that constitutes the major protein component of senile plaques in Alzheimer disease. The A4/beta protein is derived from a larger, transmembrane amyloid precursor...
Jeang, K T, Chun, R, Lin, N H, Gatignol, A, Glabe, C G, Fan, H
Recent genetic experiments have suggested that tat transactivation of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat requires functional upstream enhancer sequences--Sp1 sites,...
Full-length (86-residue) polypeptide corresponding to the human immunodeficiency virus type 1 tat trans-activating protein was chemically synthesized on a semiautomated apparatus, using an Fmoc amino...
Egg surface glycoprotein receptor for sea urchin sperm bindin.
Bindin is an insoluble protein coating the sperm acrosome process and mediating the adhesion of sperm to sea urchin eggs. Milligrams of bindin have been isolated. Here we report the identification,...
Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein.
Knauer, M F, Soreghan, B, Burdick, D, Kosmoski, J, Glabe, C G
The A4 or beta protein is a peptide that constitutes the major protein component of senile plaques in Alzheimer disease. The A4/beta protein is derived from a larger, transmembrane amyloid precursor...
Jeang, K T, Chun, R, Lin, N H, Gatignol, A, Glabe, C G, Fan, H
Recent genetic experiments have suggested that tat transactivation of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat requires functional upstream enhancer sequences--Sp1 sites,...
Full-length (86-residue) polypeptide corresponding to the human immunodeficiency virus type 1 tat trans-activating protein was chemically synthesized on a semiautomated apparatus, using an Fmoc amino...
Egg surface glycoprotein receptor for sea urchin sperm bindin.
Bindin is an insoluble protein coating the sperm acrosome process and mediating the adhesion of sperm to sea urchin eggs. Milligrams of bindin have been isolated. Here we report the identification,...