C. Heyting

Meiotic interference among MLH1 foci requires neither an intact axial element structure nor full synapsis (2007)

Boer, E., Dietrich, A.J.J., Stam, P., Heyting, C.

During meiosis, homologous chromosomes (homologs) perform reciprocal exchanges (crossovers) at a high frequency. Crossovers display interference, i.e. their spacing is more even than would be...

The mismatch repair protein MLH1 marks a subset of strongly interfering crossovers in tomato (2007)

Lhuissier, F.G.P., Offenberg, H.H., Wittich, P.E., Vischer, N.O.E., Heyting, C.

In most eukaryotes, the prospective chromosomal positions of meiotic crossovers are marked during meiotic prophase by protein complexes called late recombination nodules (LNs). In tomato (Solanum...

Two levels of interference in mouse meiotic recombination (2006)

Stam, P., Dietrich, A.J.J., Pastink, A., Heyting, C.

During meiosis, homologous chromosomes (homologs) undergo recombinational interactions, which can yield crossovers (COs) or noncrossovers. COs exhibit interference; they are more evenly spaced along...

Two levels of interference in mouse meiotic recombination (2006)

Boer, E. De, Stam, P., Dietrich, A.J.J., Pastink, A., Heyting, C.

The diverse roles of transverse filaments of synaptonemal complexes in meiosis (2006)

Heyting, C.

In most eukaryotes, homologous chromosomes (homologs) are closely apposed during the prophase of the first meiotic division by a ladderlike proteinaceous structure, the synaptonemal complex (SC)...

Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination (2004)

Revenkova, E., Eijpe, M., Heyting, C., Hodges, C.A., Hunt, P.A., Liebe, B., ...

Sister chromatid cohesion ensures the faithful segregation of chromosomes in mitosis and in both meiotic divisions1, 2, 3, 4. Meiosis-specific components of the cohesin complex, including the...

Meiotic cohesin REC8 marks the axial elements of rat synaptonemal complexes before cohesins SMC1B and SMC3 (2003)

Eijpe, M., Offenberg, H.H., Jessberger, R., Revenkova, E., Heyting, C.

In meiotic prophase, the sister chromatids of each chromosome develop a common axial element (AE) that is integrated into the synaptonemal complex (SC). We analyzed the incorporation of sister...

The pairing of X and Y chromosomes during meiotic prophase in the marsupial species Thylamys elegans is maintained by a dense plate developed from their axial elements (2003)

Page, J., Berrios, S., Rufas, J.S., Parra, M.T., Suja, J.A., Heyting, C., ...

Unlike eutherian males, pairing of the sex chromosomes in marsupial males during the first meiotic prophase is not mediated by a synaptonemal complex. Instead, a specific structure, the dense plate,...

The pairing of X and Y chromosomes during meiotic prpphase in the marsupial species Thlamys elegans is maintained by a dense plate developed from their axial elements (2002)

Page, J., Berríos, S., Rufas, J.S., Suja, J.Á., Heyting, C., Fernández-Donoso, R.

Unlike eutherian males, pairing of the sex chromosomes in marsupial males during the first meiotic prophase is not mediated by a synaptonemal complex. Instead, a specific structure, the dense plate,...

Isolation and Characterization of Sexual Sporulation Mutants of Aspergillus nidulans (2001)

Swart, K., Slakhorst, M., Debets, A.J.M., Heyting, C.

For the genetic dissection of sexual sporulation in Aspergillus nidulans, we started a collection of ascosporeless mutants. After mutagenization of conidiospores with high doses of UV, we isolated 20...

BimD/SPO76 is at the interface of cell cycle progression, chromosome morphogenesis, and recombination. (2001)

Käfer, E., Heyting, C., Zickler, D.

A novel meiosis-specific isoform of mammalian SMC1. (2001)

Revenkova, E., Eijpe, M., Heyting, C., Gross, B., Jessberger, R.

Meiotic chromosomal core consisting of cohesin complex proteins recruits DNA recombination proteins and promotes synapsis in the absence of an axial element in mammalian meiotic cells. (2001)

Pelttari, J., Hoka, M.R., Yuan, L., Liu, J.G., Brundell, E., Moens, P., ...

Association of mammalian SMC1 and SMC3 proteins with meiotic chromosomes and synaptonemal complexes (2000)

Eijpe, M., Heyting, C., Gross, B., Jessberger, R.

In somatic cells, the heterodimeric Structural Maintenance of Chromosomes (SMC) proteins are involved in chromosome condensation and gene dosage compensation (SMC2 and 4), and sister chromatid...

Localisation of RAD50 and MRE11 in spermatocyte nuclei of mouse and rat (2000)

Eijpe, M., Offenberg, H., Goedecke, W., Heyting, C.

Synaptonemal complexes (SCs) are zipperlike structures that are assembled between homologous chromosomes during meiotic prophase. They consist of two axial elements (AEs) (one along each of the two...

Analysis of male meiotic 'sex body' proteins during XY female meiosis provides new insights into their functions (2000)

Turner, J.M.A., Mahadevaiah, S.K., Benavente, R., Offenberg, H.H., Heyting, C., Burgoyne, P.S.

Sister chromatid cohesion and recombination in meiosis (2000)

Heyting, C.

Sister chromatids are associated from their formation until their disjunction. Cohesion between sister chromatids is provided by protein complexes, of which some components are conserved across the...

Mrell and Ku70 interact in somatic cells, but are differentially expressed in early meiosis (1999)

Goedecke, W., Eijpe, M., Offenberg, H.H., Heyting, C.

RADHA - a new male germ line-specific chromosomal protein of Drosophila (1999)

Harhangi, H.R., Sun, X.P., Wang, Y.X., Akhmanova, A., Miedema, K., Heyting, C., ...

Temporal and spatial control of the Sycp1 gene transcription in the mouse meiosis: regulatory elements active in the male are not sufficient for expression in the female gonad (1999)

Sage, J., Martin, L., Meuwissen, R., Heyting, C., Rassoulzadegan, M.

Isolation and characterization of the human SCP2 cDNA and chromosomal localization of the gene (1999)

Schalk, J.A.C., Offenberg, H.H., Groot, N.P.B., Hoovers, J.M.N., Heyting, C.

Isolation and characterization of the human SPC2 cDNA and chromosomal localization of the gene (1999)

Schalk, J.A.C., Offenberg, H.H., Peters, E., Groot, P.B.N., Hoovers, J.M.N., Heyting, C.

The effect of the wheat Ph1 locus on chromatin organisation and meiotic chromosome pairing analysed by genome painting. (1998)

Mikhailova, E.I., Naranjo, T., Shepherd, K., Eden, J.W., Heyting, C.

SCP2: a major protein component of the axial elements of synaptonemal complexes of the rat. (1998)

Offenberg, H.H., Schalk, J.A.C., Meuwissen, R.L.J., Kester, H.A., Dietrich, A.J.J., ...

Organization of SCP2 and SCP3 proteins within synaptonemal complexes of the rat. (1998)

Schalk, J.A.C., Dietrich, A.J.J., Vink, A.C.G., Offenberg, H.H., Heyting, C.

Polarity of meiotic recombination in the bronze locus of maize. (1998)

Thijs, H., Heyting, C.

Synaptonemal complexes. (1998)

Heyting, C.

Localization of SCP2 and SCP3 protein molecules within synaptonemal complexes of the rat (1998)

Schalk, J.A.C., Dietrich, A.J.J., Vink, A.C.G., Offenberg, H.H., Aalderen, M. Van, Heyting, C.

SCP2: a major protein component of the axial elements of synaptoneal complexes of the rat (1998)

Offenberg, H.H., Schalk, J.A.C., Meuwissen, R.L.J., Aalderen, M. Van, Kester, H.A., Dietrich, A.J.J., ...

RecA-like proteins are components of early meiotic nodules in lily. (1997)

Anderson, L.K., Offenberg, H.H., Heyting, C.

Comparative analysis of female and male meiosis in three meiotic mutants of tomato. (1997)

Havekes, F.W.J., Heyting, C.

cDNA cloning and characterization of Npap60: A novel rat nuclear pore-associated protein with an unusual subcellular localization during male germ cell differentiation. (1997)

Liu, F., Korobova, O., Heyting, C., Offenberg, H.H., Trump, G., Arnheim, N., ...

Human synaptonemal complex protein 1 (SCP1): Isolation and characterization of the cDNA and chromosomal localization of the gene. (1997)

Meuwissen, R.L.J., Meerts, I., Hoovers, J.M.N., Leschot, N.J., Heyting, C.

Analysis of A. nidulans genes involved in meiosis: uvsC, a homologue of yeast RAD51. (1997)

Swart, K., Heyting, C., Goosen, T.

Cloning, sequencing, disruption and phenotypic analysis of uvsC, an Aspergillus nidulans homologue of yeast RAD51. (1997)

Swart, K., Holub, E.F., Offenberg, H.H., Goosen, T., ...

Human synaptonemal complex protein 1 (SCP1): isolation and characterization of the cDNA and chromosomal localization in the gene (1997)

Meuwissen, R.L.J., Meerts, I., Hoovers, J.M.N., Leschot, N.J., Heyting, C.

Synaptonemal complexes: structure and function. (1996)

Heyting, C.

Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing. (1996)

Scherthan, H., Weich, S., Schwegle, H., Harle, M., Heyting, C., Cremer, T.

Organization of SCP1 protein molecules within synaptonemal complexes of the rat. (1996)

Schmekel, K., Meuwissen, R.L.J., Dietrich, A.J.J., Vink, A.C.G., ...

Rad51 in tomato. (1995)

Anderson, L.A., Offenberg, H.H., Heyting, C.

A change in the phosphorylation pattern of the 30 000 - 33 000 Mr synaptonemal complex proteins between early and mid-pachytene. (1995)

Lammers, J.H.M., Gaemers, I.C., ...

Polarity of meiotic gene conversion is 5' to 3' within the niaD gene of Aspergillus nidulans. (1995)

Thijs, J., Garde, J., Goosen, T., Tomsett, B., Swart, K., Heyting, C., ...

Isolation of genes involved in meiosis of filamentous fungi. (1995)

Goosen, T., Swart, K., Heyting, C.

Characterization of protein components of synaptonemal complexes. (1995)

Heyting, C., Meuwissen, R.L.J., Lammers, J.H.M., Schalk, J.A.C., Offenberg, H.H., ...

Meiotic chromosome pairing and crossover formation. (1995)

Heyting, C.

Synaptonemal complex proteins and DNA. (1995)

Heyting, C.

Immunocytochemical techniques applied to meiotic chromosomes. (1994)

Heyting, C., Dietrich, A.J.J., Hartsuiker, E.

Synapsis and chiasma formation in four meiotic mutants of tomato (Lycopersicon esculentum). (1994)

Havekes, F.J., Heyting, C., Ramanna, M.S.

Synapsis and recombination in meiotic mutants of the tomato. (1994)

Havekes, F.W.J., Heyting, C., Ramanna, M.S.

Synapsis and chiasma formation in four synaptic mutants of the tomato (Lycopersicon esculentum). (1994)

Havekes, F.W.J., Heyting, C., Ramanna, M.S.

Polarity of meiotic gene conversion is 5' to 3' in the niaD gene of Aspergillus nidulans. (1994)

Thijs, H., Garde, J., Goosen, T., Tomsett, B., Swart, K., Heyting, C., ...

The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes. (1994)

Lammers, J.H.M., Offenberg, H.H., Vink, A.C.G., Dietrich, A.J.J., Heyting, C.

An atomic force microscopial study of the synaptonemal complex. (1993)

Putman, C.A.J., Dietrich, A.J.J., Heyting, C., ...

Genes encoding major components of synaptonemal complexes. (1993)

Heyting, C., Offenberg, H.H., Meuwissen, R.L.J., Lammers, J.H.H., Dietrich, A.J.J.

Immunocytochemical techniques applied to meiotic chromosomes. (1993)

Heyting, C., Dietrich, A.J.J., Hartsuiker, E.

Ultrastructural evidence for a triple structure of the laterial element of the synaptonemal complex. (1993)

Dietrich, A.J.J., Heyting, C., Vink, A.C.G.

An atomic force microscopical study of the synaptonemal complex (1993)

Putman, C.A.J., Dietrich, A.J.J., Grooth, B.G. De, Marle, J. Van, Heyting, C., Hulst, N.F. Van, ...

The chromosomal structure which is specific for meiosis, the synaptonemal complex (SC), plays a major role in chromosome pairing and the recombination of genetic material. The SC was studied using...

An atomic force microscopical study of the synaptonemal complex (1993)

Dietrich, A.J.J., Grooth De, Dr. B.G., Marle Van, J., Heyting, C., Hulst Van, Prof.dr. N.F., ...

The chromosomal structure which is specific for meiosis, the synaptonemal complex (SC), plays a major role in chromosome pairing and the recombination of genetic material. The SC was studied using...

An atomic force microscopical study of the synaptonemal complex (1993)

Putman, C.A.J., Dietrich, A.J.J., Grooth De, B.G., Marle Van, J., Heyting, C., Hulst Van, N.F., ...

The chromosomal structure which is specific for meiosis, the synaptonemal complex (SC), plays a major role in chromosome pairing and the recombination of genetic material. The SC was studied using...

The sequential appearance of components of the synaptonemal complex during meiosis of the female rat. (1992)

Dietrich, A.J.J., Kok, E., Offenberg, H.H., Heyting, C., Vink, A.C.G.

Synaptonemal complexes and the organization of chromatin during meiotic prophase. (1992)

Heyting, C., Dietrich, A.J.J.

A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes. (1992)

Meuwissen, R.L.J., Offenberg, H.H., Dietrich, A.J.J., Riesewijk, A., Heyting, C.

Meiotic chromosome preparation and labeling. (1991)

Heyting, C., Dietrich, A.J.J.

Tissue distribution of two major components of synaptonemal complexes of the rat. (1991)

Offenberg, H.H., Dietrich, A.J.J., Heyting, C.

Chromosome pairing and recombination in somatic hybrids of Lycopersicon esculentum (+) Solanum tuberosum. (1991)

Wolters, J., Koornneef, M., Heyting, C.

Towards the analysis of meiosis in Aspergillus nidulans. (1991)

Swart, K., Goosen, T., Meuwissen, R.L.J., Heyting, C.

Erfgoed van de celgenetica. (1990)

Heyting, C.

Towards the cloning of meiosis specific genes from filamentous fungi. (1990)

Goosen, T., Heemst, D.W., Heyting, C., Swart, K.

The antigens recognized by three anti synaptonemal complex antibodies are specific for meiotic prophase cells. (1990)

Offenberg, H.H., Heyting, C., Redeke, E.J.W., Dietrich, A.J.J., Vink, A.C.G.

Immunocytochemical analysis of synaptonemal complexes. (1989)

Heyting, C.

Assembly of the synaptonemal complex. (1989)

Heyting, C., Offenberg, H.H., Dietrich, A.J.J.

Synaptonemal complex proteins. (1989)

Heyting, C., Dietrich, A.J.J., Dettmers, R.J., Offenberg, H.H., Redeker, E.J.W., Vink, A.C.G.

Synaptonemal complex assembly. (1989)

Heyting, C., Offenberg, H.H., Dietrich, A.J.J.

Synaptonemal complex proteins. (1989)

Offenberg, H.H., Heyting, C., Dietrich, A.J.J., Dettmers, R.J., Redeker, E.J.W., Vink, A.C.G.

Plezierig leerboek Genetica. (1989)

Heyting, C.

Novel Meiosis-Specific Isoform of Mammalian SMC1

Revenkova, E., Eijpe, M., Heyting, C., Gross, B., Jessberger, R.

Structural maintenance of chromosomes (SMC) proteins fulfill pivotal roles in chromosome dynamics. In yeast, the SMC1-SMC3 heterodimer is required for meiotic sister chromatid cohesion and DNA...

SCP2: a major protein component of the axial elements of synaptonemal complexes of the rat.

Offenberg, H H, Schalk, J A, Meuwissen, R L, Van Aalderen, M, Kester, H A, Dietrich, A J, ...

In the axial elements of synaptonemal complexes (SCs) of the rat, major protein components have been identified, with relative electrophoretic mobilities (M rs) of 30 000-33 000 and 190 000. Using...

The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes.

Lammers, J H, Offenberg, H H, Van Aalderen, M, Vink, A C, Dietrich, A J, Heyting, C

The lateral elements of synaptonemal complexes (SCs) of the rat contain major components with relative electrophoretic mobilities (M(r)S) of 30,000 and 33,000. After one-dimensional separation of SC...

A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes.

Meuwissen, R L, Offenberg, H H, Dietrich, A J, Riesewijk, A, Van Iersel, M, Heyting, C

Synaptonemal complexes (SCs) are structures that are formed between homologous chromosomes during meiotic prophase. They are probably involved in chromosome pairing and recombination. Using a...

Polarity of Meiotic Recombination in the bronze Locus of Maize

Thijs, H., Heyting, C.

Novel Meiosis-Specific Isoform of Mammalian SMC1

Revenkova, E., Eijpe, M., Heyting, C., Gross, B., Jessberger, R.

Structural maintenance of chromosomes (SMC) proteins fulfill pivotal roles in chromosome dynamics. In yeast, the SMC1-SMC3 heterodimer is required for meiotic sister chromatid cohesion and DNA...

SCP2: a major protein component of the axial elements of synaptonemal complexes of the rat.

Offenberg, H H, Schalk, J A, Meuwissen, R L, Van Aalderen, M, Kester, H A, Dietrich, A J, ...