Sluijter, B.J., Moesbergen, L.M., Gruijl, T.D., Molenkamp, B.G., ...
In this study we investigated whether the presence of specific populations of tumor infiltrating lymphocytes (TILs) in diagnostic primary melanoma biopsies are related to outcome in clinically stage...
Motivational interviewing in psychotic disorders (2006)
Barkhof, E., Haan, L. De, Meijer, C.J., Fouwels, A.J., Keet, I.P.M., Hulstijn, K.P., ...
Heideman, D.A.M., Overmeer, R.M., Beusechem, V.W. Van, Lamers, W.H., Hakvoort, T.B.M., Snijders, P.J., ...
Mensen met schyzofrenie: de zorg in een urbane en een rurale regio vergeleken [hfdstk 7] (2004)
Schene, A.H., Meijer, C.J., Koeter, M.W.J., Wijngaarden, B. Van, Monden, M.A.H.
Jacobs, M V, De Roda Husman, A M, Van Den Brule, A J, Snijders, P J, Meijer, C J, Walboomers, J M
In recent years, general primer-mediated PCR assays have been developed to detect a broad spectrum of human papillomavirus (HPV) genotypes. In this study, a procedure enabling a simple group-specific...
Lan, J, Melgers, I, Meijer, C J, Walboomers, J M, Roosendaal, R, Burger, C, ...
The prevalence rates and serovar distributions of Chlamydia trachomatis cervical infections were investigated in two different groups of women. Group I consisted of 393 asymptomatic young women (aged...
Morré, S A, Sillekens, P, Jacobs, M V, Van Aarle, P, De Blok, S, Van Gemen, B, ...
In the present study, the suitability of RNA amplification by nucleic acid sequence-based amplification (NASBA) for the detection of Chlamydia trachomatis infection was investigated. When comparing...
Jacobs, M V, Snijders, P J, Van Den Brule, A J, Helmerhorst, T J, Meijer, C J, Walboomers, J M
Two cocktails of digoxigenin-labeled human papillomavirus (HPV) type-specific oligonucleotide probes and an enzyme immunoassay (EIA) were used as a basis to developed a group-specific detection...
Snijders, P J, Van Den Brule, A J, Schrijnemakers, H F, Raaphorst, P M, Meijer, C J, Walboomers, J M
Human papillomavirus type 33 (HPV-33)-specific early region transcripts in a tonsillar carcinoma were analyzed by using the RNA polymerase chain reaction method. A total of five cDNA species...
Lan, J, Walboomers, J M, Roosendaal, R, Van Doornum, G J, MacLaren, D M, Meijer, C J, ...
Detection and genotyping of Chlamydia trachomatis were optimized by using a polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis performed directly with crude...
Direct PCR enables detection of Mycoplasma pneumoniae in patients with respiratory tract infections.
Tjhie, J H, Van Kuppeveld, F J, Roosendaal, R, Melchers, W J, Gordijn, R, MacLaren, D M, ...
The sensitivities of three methods of detection of Mycoplasma pneumoniae by a 16S rDNA PCR were compared by using a serial dilution of M. pneumoniae. These methods consisted of a PCR performed...
Lan, J, Ossewaarde, J M, Walboomers, J M, Meijer, C J, Van Den Brule, A J
Successful amplification of omp1 DNA by PCR is crucial in the genotyping of Chlamydia trachomatis when directly performed with clinical samples (J. Lan, J. M. M. Walboomers, R. Roosendaal, G. J. van...
Van Den Brule, A J, Snijders, P J, Raaphorst, P M, Schrijnemakers, H F, Delius, H, Gissmann, L, ...
We recently described the detection of potentially novel human papillomaviruses (HPV) genotypes (HPV types X [HPV X]) in cervical smears (A. J. C. van den Brule, C. J. L. M. Meijer, V. Bakels, P....
Melchers, W J, Herbrink, P, Walboomers, J M, Meijer, C J, Vd Drift, H, Lindeman, J, ...
Optimal conditions for the screening of cervical scrapes for human papillomavirus (HPV) were investigated by using filter in situ hybridization. Since integrated and episomal HPV can be found, cell...
Van Den Brule, A J, Meijer, C J, Bakels, V, Kenemans, P, Walboomers, J M
A two-step polymerase chain reaction (PCR) procedure was used as a new screening strategy for the detection of human papillomavirus (HPV) genotypes in cervical scrapes omitting prior DNA extraction....
Correlation of cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer.
De Jong, J S, Van Diest, P J, Michalides, R J, Meijer, C J, Baak, J P
BACKGROUND: In vitro studies have shown that amplification and overexpression of the cyclin D1 gene can accelerate the progress of cells through the G1 phase. Therefore, cyclin D1 may have an...
Morré, S A, Sillekens, P T, Jacobs, M V, De Blok, S, Ossewaarde, J M, Van Aarle, P, ...
AIM: To investigate the value of RNA detection by nucleic acid sequence based amplification (NASBA) for the monitoring of Chlamydia trachomatis infections after antibiotic treatment. METHODS:...
Hayes, D P, Brink, A A, Vervoort, M B, Middeldorp, J M, Meijer, C J, Van Den Brule, A J
AIMS: To examine the expression of Epstein-Barr virus (EBV) transcripts encoding proteins homologous to important human proteins in diverse EBV associated diseases. The proteins were: BHRF1...
Use of monoclonal antibody E48 in diagnosing transitional cell carcinoma of urinary bladder.
Torenbeek, R, Blomjous, C E, Quak, J J, Ybema, S, Meijer, C J
AIMS: To investigate the localisation of the E48 epitope and to determine the use of monoclonal antibody E48 for the identification of transitional cell carcinomas (TCC); and to determine if...
Seldenrijk, C A, Meuwissen, S G, Schipper, N W, Morson, B C, Lindeman, J, Meijer, C J
AIMS: To investigate whether counting cells containing immunoglobulin (Ig) subclass in colonic biopsy specimens of patients with chronic inflammatory bowel disease, in addition to conventional...
Analysis of large-cell lymphomas using monoclonal and heterologous antibodies.
Fifteen cases of large-cell lymphoma, diagnosed as centroblastic (5), B-immunoblastic (5) or true histiocytic (5). lymphoma and one case of malignant histiocytosis were studied with monoclonal...
Morphometric characterisation of 52 B cell non-Hodgkin's lymphomas.
Mosch, A, Kurver, P J, Meijer, C J
Fifty-two B cell non-Hodgkin's lymphomas, in which the diagnosis was based on immunological, cytochemical, and ultrastructural studies, were characterised by morphometry on plastic-embedded tissue...
Herbrink, P, Meenhorst, P L, Groothuis, D G, Munckhof, H V, Bax, R, Meijer, C J, ...
One hundred and seventy-five human sera were tested for the presence of type-specific antibodies against L pneumophila serogroups 1 to 6 and the Leiden-1 strain by means of an enzyme linked...
Van Spreeuwel, J P, Lindeman, J, Meijer, C J
In colonic biopsies of 33 patients with acute colitis caused by campylobacter, salmonella, or shigella immunoglobulin containing cells were determined quantitatively using an indirect...
Brink, A A, Dukers, D F, Van Den Brule, A J, Oudejans, J J, Middeldorp, J M, Meijer, C J, ...
AIMS: To investigate the expression pattern of Epstein-Barr virus (EBV) latent genes at the single cell level in post-transplantation lymphoproliferative disorders and acquired immunodefiency...
Bakels, V, Van Oostveen, J W, Preesman, A H, Meijer, C J, Willemze, R
AIMS: Differentiation between actinic reticuloid and cutaneous T cell lymphoma can be extremely difficult. Demonstration of clonal T cell receptor (TCR) gene rearrangements has been suggested as a...
Oudejans, J J, Dukers, D F, Jiwa, N M, Van Den Brule, A J, Grässer, F A, De Bruin, P C, ...
AIMS: To determine levels of expression of Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) in benign and malignant tissues harbouring EBV in relation to EBNA1 promoter usage. METHODS: Expression...
A cytotoxic phenotype does not predict clinical outcome in anaplastic large cell lymphomas.
Dukers, D F, Ten Berge, R L, Oudejans, J J, Pulford, K, Hayes, D, Miseré, J F, ...
AIM: To investigate whether anaplastic large cell lymphomas (ALCL) expressing cytotoxic proteins have a relatively worse clinical outcome compared with ALCL lacking a cytotoxic phenotype. METHODS: 59...
Jiwa, N M, Kanavaros, P, Walboomers, J M, Horstman, A, Vos, W, ...
AIMS: To evaluate the expression of c-myc and bcl-2 oncogene products in Reed-Sternberg cells in Hodgkin's disease, especially in relation to Epstein-Barr virus infection and expression of EBV...
Lagendijk, J H, Mullink, H, Van Diest, P J, Meijer, G A, Meijer, C J
AIM: To discriminate between adenocarcinomas that are primary to the ovary and metastatic to the ovary, especially of colonic and breast origin, by immunohistochemistry, using stepwise discriminant...
Jacobs, M V, Snijders, P J, Voorhorst, F J, Dillner, J, Forslund, O, Johansson, B, ...
BACKGROUND: The development of a reproducible, sensitive, and standardised human papillomavirus (HPV) polymerase chain reaction (PCR) test is required to implement HPV testing in cervical cancer...
Prognostic importance of DNA flow cytometric variables in rhabdomyosarcomas.
Wijnaendts, L C, Van Der Linden, J C, Van Diest, P, Van Unnik, A J, Delemarre, J F, Voûte, P A, ...
AIM--To determine whether DNA ploidy patterns and S phase fraction offer prognostic information in patients with rhabdomyosarcoma (RMS). METHODS--DNA flow cytometry was performed on formalin fixed,...
Relation of CD30 expression to survival and morphology in large cell B cell lymphomas.
Noorduyn, L A, De Bruin, P C, Van Heerde, P, Van De Sandt, M M, Ossenkoppele, G J, Meijer, C J
AIMS--To investigate whether CD30 expression is correlated with anaplastic morphology, and whether this correlated with a better survival in large cell B cell lymphomas, as has been described for T...
Morphometric and flow cytometric analysis of small cell undifferentiated carcinoma of the bladder.
Blomjous, C E, Vos, W, Schipper, N W, De Voogt, H J, Baak, J P, Meijer, C J
Eighteen cases of primary small cell carcinoma of the bladder were studied. Three patients survived for two years and one survived for five years, which was significantly worse when compared with...
Jaspars, E H, Bloemena, E, Bonnet, P, Scheper, R J, Kaiserling, E, Meijer, C J
AIMS--To develop a monoclonal antibody specific for human macrophages in routinely processed material. METHODS--The monoclonal antibody was derived from a mouse popliteal lymph node after...
Jiwa, N M, Oudejans, J J, Dukers, D F, Vos, W, Horstman, A, ...
AIM--To compare the immunoreactivity of monoclonal antibodies S12 and CS1-4, which recognise different epitopes of the Epstein-Barr virus (EBV) latent membrane protein-1 (LMP-1), in EBV associated...
Distribution of OV-TL 3 and MOv18 in normal and malignant ovarian tissue.
Buist, M R, Molthoff, C F, Kenemans, P, Meijer, C J
AIMS--To analyse the distribution of OV-TL 3 and MOv18 in normal ovarian tissue to determine which antibody is most suitable for (radio)immunotherapy of ovarian carcinoma. METHODS--The distribution...
Walboomers, J M, De Roda Husman, A M, Snijders, P J, Stel, H V, Risse, E K, Helmerhorst, T J, ...
AIM--To assess the value of detecting human papillomavirus (HPV) DNA in false negative archival cervical smears in population based screening programmes for cervical cancer....
Lan, J, Van Den Brule, A J, Hemrika, D J, Risse, E K, Walboomers, J M, Schipper, M E, ...
AIMS--To examine the role of Chlamydia trachomatis in ectopic pregnancy by detection of DNA in archival salpingectomy specimens, and in their preceding cervical specimens and endometrial biopsies, by...
Expression of Epstein-Barr virus encoded latent genes in nasal T cell lymphomas.
Van Gorp, J, Brink, A, Oudejans, J J, Van Den Brule, A J, Van Den Tweel, J G, Jiwa, N M, ...
AIMS: To determine the expression of Epstein-Barr (EB) virus encoded latent genes in nasal T-cell lymphomas in The Netherlands. METHODS: Seven europid (Dutch) cases of nasal T cell lymphoma were...
Rosekrans, P C, Meijer, C J, Cornelisse, C J, Van Der Wal, A M, Lindeman, J
Eight babies with cow's milk protein intolerance and malabsorption, ages ranging from 2 weeks to 6 months, and five adult patients with a history of food allergy were studied. In the jejunal biopsies...
Rosekrans, P C, Meijer, C J, Polanco, I, Mearin, M L, Van Der Wal, A M, Lindeman, J
Jejunal biopsy specimens from nine Spanish children with gluten-sensitive enteropathy were studied with morphometric and immunohistochemical techniques in three stages of the diseases: the first...
Jacobs, M V, De Roda Husman, A M, Van Den Brule, A J, Snijders, P J, Meijer, C J, Walboomers, J M
In recent years, general primer-mediated PCR assays have been developed to detect a broad spectrum of human papillomavirus (HPV) genotypes. In this study, a procedure enabling a simple group-specific...
Lan, J, Melgers, I, Meijer, C J, Walboomers, J M, Roosendaal, R, Burger, C, ...
The prevalence rates and serovar distributions of Chlamydia trachomatis cervical infections were investigated in two different groups of women. Group I consisted of 393 asymptomatic young women (aged...
Morré, S A, Sillekens, P, Jacobs, M V, Van Aarle, P, De Blok, S, Van Gemen, B, ...
In the present study, the suitability of RNA amplification by nucleic acid sequence-based amplification (NASBA) for the detection of Chlamydia trachomatis infection was investigated. When comparing...
Jacobs, M V, Snijders, P J, Van Den Brule, A J, Helmerhorst, T J, Meijer, C J, Walboomers, J M
Two cocktails of digoxigenin-labeled human papillomavirus (HPV) type-specific oligonucleotide probes and an enzyme immunoassay (EIA) were used as a basis to developed a group-specific detection...
Snijders, P J, Van Den Brule, A J, Schrijnemakers, H F, Raaphorst, P M, Meijer, C J, Walboomers, J M
Human papillomavirus type 33 (HPV-33)-specific early region transcripts in a tonsillar carcinoma were analyzed by using the RNA polymerase chain reaction method. A total of five cDNA species...
Lan, J, Walboomers, J M, Roosendaal, R, Van Doornum, G J, MacLaren, D M, Meijer, C J, ...
Detection and genotyping of Chlamydia trachomatis were optimized by using a polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis performed directly with crude...
Direct PCR enables detection of Mycoplasma pneumoniae in patients with respiratory tract infections.
Tjhie, J H, Van Kuppeveld, F J, Roosendaal, R, Melchers, W J, Gordijn, R, MacLaren, D M, ...
The sensitivities of three methods of detection of Mycoplasma pneumoniae by a 16S rDNA PCR were compared by using a serial dilution of M. pneumoniae. These methods consisted of a PCR performed...
Lan, J, Ossewaarde, J M, Walboomers, J M, Meijer, C J, Van Den Brule, A J
Successful amplification of omp1 DNA by PCR is crucial in the genotyping of Chlamydia trachomatis when directly performed with clinical samples (J. Lan, J. M. M. Walboomers, R. Roosendaal, G. J. van...
Van Den Brule, A J, Snijders, P J, Raaphorst, P M, Schrijnemakers, H F, Delius, H, Gissmann, L, ...
We recently described the detection of potentially novel human papillomaviruses (HPV) genotypes (HPV types X [HPV X]) in cervical smears (A. J. C. van den Brule, C. J. L. M. Meijer, V. Bakels, P....
Melchers, W J, Herbrink, P, Walboomers, J M, Meijer, C J, Vd Drift, H, Lindeman, J, ...
Optimal conditions for the screening of cervical scrapes for human papillomavirus (HPV) were investigated by using filter in situ hybridization. Since integrated and episomal HPV can be found, cell...
Van Den Brule, A J, Meijer, C J, Bakels, V, Kenemans, P, Walboomers, J M
A two-step polymerase chain reaction (PCR) procedure was used as a new screening strategy for the detection of human papillomavirus (HPV) genotypes in cervical scrapes omitting prior DNA extraction....
Correlation of cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer.
De Jong, J S, Van Diest, P J, Michalides, R J, Meijer, C J, Baak, J P
BACKGROUND: In vitro studies have shown that amplification and overexpression of the cyclin D1 gene can accelerate the progress of cells through the G1 phase. Therefore, cyclin D1 may have an...
Morré, S A, Sillekens, P T, Jacobs, M V, De Blok, S, Ossewaarde, J M, Van Aarle, P, ...
AIM: To investigate the value of RNA detection by nucleic acid sequence based amplification (NASBA) for the monitoring of Chlamydia trachomatis infections after antibiotic treatment. METHODS:...
Hayes, D P, Brink, A A, Vervoort, M B, Middeldorp, J M, Meijer, C J, Van Den Brule, A J
AIMS: To examine the expression of Epstein-Barr virus (EBV) transcripts encoding proteins homologous to important human proteins in diverse EBV associated diseases. The proteins were: BHRF1...
Use of monoclonal antibody E48 in diagnosing transitional cell carcinoma of urinary bladder.
Torenbeek, R., Blomjous, C. E., Quak, J. J., Ybema, S., Meijer, C. J.
AIMS: To investigate the localisation of the E48 epitope and to determine the use of monoclonal antibody E48 for the identification of transitional cell carcinomas (TCC); and to determine if...
Seldenrijk, C. A., Meuwissen, S. G., Schipper, N. W., Morson, B. C., Lindeman, J., Meijer, C. J.
AIMS: To investigate whether counting cells containing immunoglobulin (Ig) subclass in colonic biopsy specimens of patients with chronic inflammatory bowel disease, in addition to conventional...
Analysis of large-cell lymphomas using monoclonal and heterologous antibodies.
Fifteen cases of large-cell lymphoma, diagnosed as centroblastic (5), B-immunoblastic (5) or true histiocytic (5). lymphoma and one case of malignant histiocytosis were studied with monoclonal...
Morphometric characterisation of 52 B cell non-Hodgkin's lymphomas.
Mosch, A, Kurver, P J, Meijer, C J
Fifty-two B cell non-Hodgkin's lymphomas, in which the diagnosis was based on immunological, cytochemical, and ultrastructural studies, were characterised by morphometry on plastic-embedded tissue...
Herbrink, P, Meenhorst, P L, Groothuis, D G, Munckhof, H V, Bax, R, Meijer, C J, ...
One hundred and seventy-five human sera were tested for the presence of type-specific antibodies against L pneumophila serogroups 1 to 6 and the Leiden-1 strain by means of an enzyme linked...
Van Spreeuwel, J P, Lindeman, J, Meijer, C J
In colonic biopsies of 33 patients with acute colitis caused by campylobacter, salmonella, or shigella immunoglobulin containing cells were determined quantitatively using an indirect...
Brink, A A, Dukers, D F, Van Den Brule, A J, Oudejans, J J, Middeldorp, J M, Meijer, C J, ...
AIMS: To investigate the expression pattern of Epstein-Barr virus (EBV) latent genes at the single cell level in post-transplantation lymphoproliferative disorders and acquired immunodefiency...
Bakels, V, Van Oostveen, J W, Preesman, A H, Meijer, C J, Willemze, R
AIMS: Differentiation between actinic reticuloid and cutaneous T cell lymphoma can be extremely difficult. Demonstration of clonal T cell receptor (TCR) gene rearrangements has been suggested as a...
Oudejans, J J, Dukers, D F, Jiwa, N M, Van Den Brule, A J, Grässer, F A, De Bruin, P C, ...
AIMS: To determine levels of expression of Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) in benign and malignant tissues harbouring EBV in relation to EBNA1 promoter usage. METHODS: Expression...
A cytotoxic phenotype does not predict clinical outcome in anaplastic large cell lymphomas.
Dukers, D F, Ten Berge, R L, Oudejans, J J, Pulford, K, Hayes, D, Miseré, J F, ...
AIM: To investigate whether anaplastic large cell lymphomas (ALCL) expressing cytotoxic proteins have a relatively worse clinical outcome compared with ALCL lacking a cytotoxic phenotype. METHODS: 59...
Jiwa, N M, Kanavaros, P, Walboomers, J M, Horstman, A, Vos, W, ...
AIMS: To evaluate the expression of c-myc and bcl-2 oncogene products in Reed-Sternberg cells in Hodgkin's disease, especially in relation to Epstein-Barr virus infection and expression of EBV...
Lagendijk, J H, Mullink, H, Van Diest, P J, Meijer, G A, Meijer, C J
AIM: To discriminate between adenocarcinomas that are primary to the ovary and metastatic to the ovary, especially of colonic and breast origin, by immunohistochemistry, using stepwise discriminant...
Jacobs, M V, Snijders, P J, Voorhorst, F J, Dillner, J, Forslund, O, Johansson, B, ...
BACKGROUND: The development of a reproducible, sensitive, and standardised human papillomavirus (HPV) polymerase chain reaction (PCR) test is required to implement HPV testing in cervical cancer...
Prognostic importance of DNA flow cytometric variables in rhabdomyosarcomas.
Wijnaendts, L C, Van Der Linden, J C, Van Diest, P, Van Unnik, A J, Delemarre, J F, Voûte, P A, ...
AIM--To determine whether DNA ploidy patterns and S phase fraction offer prognostic information in patients with rhabdomyosarcoma (RMS). METHODS--DNA flow cytometry was performed on formalin fixed,...
Relation of CD30 expression to survival and morphology in large cell B cell lymphomas.
Noorduyn, L A, De Bruin, P C, Van Heerde, P, Van De Sandt, M M, Ossenkoppele, G J, Meijer, C J
AIMS--To investigate whether CD30 expression is correlated with anaplastic morphology, and whether this correlated with a better survival in large cell B cell lymphomas, as has been described for T...
Morphometric and flow cytometric analysis of small cell undifferentiated carcinoma of the bladder.
Blomjous, C E, Vos, W, Schipper, N W, De Voogt, H J, Baak, J P, Meijer, C J
Eighteen cases of primary small cell carcinoma of the bladder were studied. Three patients survived for two years and one survived for five years, which was significantly worse when compared with...
Jaspars, E H, Bloemena, E, Bonnet, P, Scheper, R J, Kaiserling, E, Meijer, C J
AIMS--To develop a monoclonal antibody specific for human macrophages in routinely processed material. METHODS--The monoclonal antibody was derived from a mouse popliteal lymph node after...
Jiwa, N M, Oudejans, J J, Dukers, D F, Vos, W, Horstman, A, ...
AIM--To compare the immunoreactivity of monoclonal antibodies S12 and CS1-4, which recognise different epitopes of the Epstein-Barr virus (EBV) latent membrane protein-1 (LMP-1), in EBV associated...
Distribution of OV-TL 3 and MOv18 in normal and malignant ovarian tissue.
Buist, M R, Molthoff, C F, Kenemans, P, Meijer, C J
AIMS--To analyse the distribution of OV-TL 3 and MOv18 in normal ovarian tissue to determine which antibody is most suitable for (radio)immunotherapy of ovarian carcinoma. METHODS--The distribution...
Walboomers, J M, De Roda Husman, A M, Snijders, P J, Stel, H V, Risse, E K, Helmerhorst, T J, ...
AIM--To assess the value of detecting human papillomavirus (HPV) DNA in false negative archival cervical smears in population based screening programmes for cervical cancer....
Lan, J, Van Den Brule, A J, Hemrika, D J, Risse, E K, Walboomers, J M, Schipper, M E, ...
AIMS--To examine the role of Chlamydia trachomatis in ectopic pregnancy by detection of DNA in archival salpingectomy specimens, and in their preceding cervical specimens and endometrial biopsies, by...
Expression of Epstein-Barr virus encoded latent genes in nasal T cell lymphomas.
Van Gorp, J, Brink, A, Oudejans, J J, Van Den Brule, A J, Van Den Tweel, J G, Jiwa, N M, ...
AIMS: To determine the expression of Epstein-Barr (EB) virus encoded latent genes in nasal T-cell lymphomas in The Netherlands. METHODS: Seven europid (Dutch) cases of nasal T cell lymphoma were...
Rosekrans, P C, Meijer, C J, Cornelisse, C J, Van Der Wal, A M, Lindeman, J
Eight babies with cow's milk protein intolerance and malabsorption, ages ranging from 2 weeks to 6 months, and five adult patients with a history of food allergy were studied. In the jejunal biopsies...
Rosekrans, P C, Meijer, C J, Polanco, I, Mearin, M L, Van Der Wal, A M, Lindeman, J
Jejunal biopsy specimens from nine Spanish children with gluten-sensitive enteropathy were studied with morphometric and immunohistochemical techniques in three stages of the diseases: the first...
Westedt, M L, Vermeer, B J, Meijer, C J, Daha, M R, Baldwin, W M, Cats, A
Fifty two patients with seropositive rheumatoid arthritis (RA) were studied over a period of one year to investigate possible relationships among changes of circulating immune complexes (CIC),...
Food intolerance in rheumatoid arthritis. II. Clinical and histological aspects.
Van De Laar, M A, Aalbers, M, Bruins, F G, Van Der Korst, J K, Meijer, C J
Six patients with rheumatoid factor positive rheumatoid arthritis who had shown a marked symptomatic improvement during four weeks of hypoallergic, artificial diet were studied in greater detail....
Pals, S T, Scheper, R J, Meijer, C J
OBJECTIVES--It has previously been shown that the very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway functions as a receptor/ligand interaction system mediating the...
Bijl, J. J., Rieger, E., Van Oostveen, J. W., Walboomers, J. M., Kreike, M., Willemze, R., ...
Homeobox (HOX) genes are involved in the lineage-specific differentiation of bone marrow stem cells. Recently, we reported a largely similar expression pattern of HOXC4 and HOXC6 in normal and...
Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value.
Van Diest, P. J., Michalides, R. J., Jannink, L., Peterse, H. L., De Jong, J. S., ...
Cyclin D1 overexpression, detected by standard immunohistochemistry, was correlated with other prognostic variables and its prognostic value was evaluated in a group of 148 invasive breast cancers...
Bakels, V., Van Oostveen, J. W., Van Der Putte, S. C., Meijer, C. J., Willemze, R.
Differentiation between cutaneous pseudo-T-cell lymphomas and cutaneous T-cell lymphomas (CTCLs) may be extremely difficult. In this study, it was investigated whether demonstration of an aberrant...
Tissue distribution of the multidrug resistance protein.
Flens, M. J., Zaman, G. J., Izquierdo, M. A., Schroeijers, A. B., Scheffer, G. L., ...
The human multidrug resistance protein (MRP) is a 190 kd membrane glycoprotein that can cause resistance of human tumor cells to various anticancer drugs, by extruding these drugs out of the cell....
Granzyme B expression in Reed-Sternberg cells of Hodgkin's disease.
Oudejans, J. J., Kummer, J. A., Jiwa, M., Ossenkoppele, G. J., Kluin, P. M., ...
Reed-Sternberg (RS) and Hodgkin's (H) cells are considered to be the neoplastic cells in Hodgkin's disease. Although most data suggest a lymphoid origin, the nature of these cells still remains the...
Izquierdo, M. A., Scheffer, G. L., Flens, M. J., Giaccone, G., Broxterman, H. J., Meijer, C. J., ...
Multidrug resistance (MDR) to anticancer drugs is a major cause of treatment failure in cancer. The lung resistance protein LRP is a newly described protein related to MDR in several in vitro models....
De Bruin, P. C., Jiwa, N. M., Oudejans, J. J., Radaszkiewicz, T., Meijer, C. J.
Forty-three primary gastrointestinal T cell lymphomas were investigated for the presence of Epstein-Barr virus (EBV) by polymerase chain reaction, RNA in situ hybridization, and immunohistochemistry....
Oudejans, J. J., Jiwa, M., Van Den Brule, A. J., Grässer, F. A., Horstman, A., Vos, W., ...
Using RT-PCR analysis of Epstein-Barr virus (EBV) latent gene transcription in EBV-harboring cell lines (JY and RAJI) and in post-transplantation lymphoproliferative disorders (PT-LPDs), we detected...
Quak, J. J., Balm, A. J., Van Dongen, G. A., Brakkee, J. G., Scheper, R. J., Snow, G. B., ...
After immunization of mice with viable cells of a metastasis of a laryngeal squamous cell carcinoma, a monoclonal antibody E 48 was obtained that detects an epitope present exclusively in squamous...
Snijders, P. J., Schulten, E. A., Mullink, H., Ten Kate, R. W., Jiwa, M., ...
The presence of human papillomavirus (HPV) and Epstein-Barr virus (EBV) was analyzed in 21 oral biopsy specimens of HIV-infected patients using the polymerase chain reaction (PCR) method. Biopsies...
Beljaards, R. C., Meijer, C. J., Scheffer, E., Toonstra, J., Van Vloten, W. A., Van Der Putte, S. C., ...
The histologic and immunophenotypical features of 20 primary cutaneous large-cell lymphomas of T-cell origin were investigated and correlated with clinical data to obtain prognostically relevant...
Duijvestijn, A. M., Horst, E., Pals, S. T., Rouse, B. N., Steere, A. C., Picker, L. J., ...
Lymphocyte traffic into lymph nodes and into mucosa-associated lymphoid tissues is regulated by specialized postcapillary high endothelial venules (HEVs). The authors have produced a rat monoclonal...
Walboomers, J. M., Melchers, W. J., Mullink, H., Meijer, C. J., Struyk, A., Quint, W. G., ...
The sensitivity of human papilloma virus type 16 (HPV-16) DNA detection by DNA in situ hybridization using biotinylated probes (bio-DISH) was estimated by performing this technique on snap-frozen...
Seldenrijk, C A, Drexhage, H A, Meuwissen, S G, Meijer, C J
A mycobacterial aetiology has been suggested for Crohn's disease. A slow growing mycobacterium, biochemically and genetically identical to M paratuberculosis, the causative agent of enteritis in...
Seldenrijk, C A, Morson, B C, Meuwissen, S G, Schipper, N W, Lindeman, J, Meijer, C J
In a prospective blind evaluation of multiple colonic mucosal biopsy specimens, 45 clinically well defined patients with chronic inflammatory bowel disease (21 Crohn's disease and 24 ulcerative...
Rosekrans, P C, Meijer, C J, Van Der Wal, A M, Cornelisse, C J, Lindeman, J
Immunoglobulin containing cells in rectal and sigmoid colonic mucosa in endoscopically obtained biopsies from 10 patients with ulcerative colitis and 10 patients with Crohn's disease were studied,...
Allergic proctitis, a clinical and immunopathological entity.
Rosekrans, P C, Meijer, C J, Van Der Wal, A M, Lindeman, J
Patients with isolated ulcerative proctitis form a heterogeneous group. Some may develop ulcerative colitis, others have a limited, benign disease. Twelve patients with isolated proctitis with a mean...
Campylobacter colitis: histological immunohistochemical and ultrastructural findings.
Van Spreeuwel, J P, Duursma, G C, Meijer, C J, Bax, R, Rosekrans, P C, Lindeman, J
The colonic biopsy specimens of 22 patients with colitis and positive stool cultures for Campylobacter jejuni were studied in order to obtain histological and immunohistochemical criteria to...
Dendritic cells and scavenger macrophages in chronic inflammatory bowel disease.
Seldenrijk, C A, Drexhage, H A, Meuwissen, S G, Pals, S T, Meijer, C J
We used enzyme (acid phosphatase [AP]) and immunohistochemical techniques and a set of monoclonal antibodies (CD11, CD5, CD4, CD19, CD8, OKIa), including two recently developed antibodies--for...
Van Den Brule, A. J., Cromme, F. V., Snijders, P. J., Smit, L., Oudejans, C. B., Baak, J. P., ...
Paraffin-embedded squamous cell carcinomas of the uterine cervix selected for the presence of human papillomavirus (HPV) genotype 16 (n = 19) by polymerase chain reaction, were studied for...
Expression of developmentally regulated muscle proteins in rhabdomyosarcomas.
Wijnaendts, L. C., Van Der Linden, J. C., Van Unnik, A. J., Delemarre, J. F., Barbet, J. P., Butler-Browne, G. S., ...
Human skeletal muscle differentiation and maturation follows a precise sequence of events. To investigate whether and to what extent rhabdomyosarcoma (RMS) cells follow a comparable sequence, 29...
Willemze, R., Scheffer, E., Meijer, C. J.
Using an indirect immunoperoxidase technique and a panel of monoclonal antibodies with well-defined specificities, the authors studied the distribution of lymphoid and nonlymphoid cells in the T-cell...
Willemze, R., Cornelisse, C. J., Hermans, J., Pardoel, V. P., Van Vloten, W. A., Meijer, C. J.
Previous studies have demonstrated that quantitative analysis of nuclear convolution of lymphoid cells in electron micrographs is a valuable method of differentiation between well-established...
Multidrug resistance gene (P-glycoprotein) expression in the human fetus.
Van Kalken, C., Giaccone, G., Kuiper, C. M., Hadisaputro, M. M., Bosma, S. A., ...
P-glycoprotein, a transmembrane protein associated with multidrug resistance in cancer cells, is also expressed in normal tissues. To get more insight into the physiologic role of...
Willemze, R., Meijer, C. J., Scheffer, E., Kluin, P. M., Van Vloten, W. A., Toonstra, J., ...
This report describes the clinical, histologic, and immunologic characteristics of 16 diffuse large cell lymphomas of follicular center cell origin with only skin lesions at presentation. These...
Immunohistochemical studies of the spleen in hairy-cell leukemia.
Meijer, C. J., Albeda, F., Spaander, P. J., Jansen, J.
Immunohistochemical studies of 10 spleens from patients with hairy-cell leukemia (HCL) with a battery of monoclonal and heterologous antibodies were performed in order to obtain information on the...
Kummer, J A, Kamp, A M, Tadema, T M, Vos, W, Meijer, C J, Hack, C E
Cytoplasmic granules from activated natural killer (NK) and cytotoxic T lymphocytes (CTL) contain a pore-forming protein, perforin, and several homologous serine proteinases called granzymes....
Autoantibodies against Tmu and B lymphocytes in patients with rheumatoid arthritis.
Meijer, C J, Cnossen, J, Lafeber, G J, Damsteeg, M J, Cats, A
Patients with rheumatoid arthritis have decreased numbers of T mu lymphocytes in their peripheral blood. To find out whether these low number of T mu lymphocytes were associated with the presence of...
Kauffmann, R H, Herrmann, W A, Meijer, C J, Daha, M R, Vanes, L A
Sixty-two patients with allergic vasculitis and histological evidence of leukocytoclastic vasculitis were examined to determine whether clinical features, such as course and degree of systemic...
T lymphocyte function in hairy cell leukaemia.
Sabbe, L J, Meijer, C J, Jansen, J
The high incidence of infections characteristic of impaired cell-mediated immunity in patients with hairy cell leukemia led us to study T lymphocyte function in sixteen patients with the lymphocyte...
Van Der Loo, E M, Cnossen, J, Meijer, C J
Cerebriform mononuclear cells (CMC) constitute a morphologically distinct subpopulation of T cells in healthy individuals. They are characterized ultrastructurally by a highly indented nucleus, a...
Scheeren, R A, Oostendorp, R A, Keehnen, R M, Scheper, R J, Meijer, C J
In patients with head and neck carcinomas and in patients with chronic purulent upper airway infections, low molecular weight retroviral p15E-like factors are found. These factors are responsible for...
Morphometric characterization of diffuse large-cell (histiocytic) lymphomas.
Hermans, J., Brand, R., Cornelisse, C. J., Spaander, P. J., Meijer, C. J.
From 28 large-cell lymphomas, defined by marker studies, enzyme histochemistry, and electron microscopy as large noncleaved follicle center cell tumors (lnc FCC), B-immunoblastic or true histiocytic...
Localisation of a low-molecular-weight bronchial protease inhibitor in the peripheral human lung.
Mooren, H W, Kramps, J A, Franken, C, Meijer, C J, Dijkman, J A
The localisation of a low-molecular-weight bronchial protease inhibitor (LMI) in human peripheral lung tissue was studied by an immunohistochemical method. This inhibitor was found exclusively in a...
Lan, J, Meijer, C J, Van Den Hoek, A R, Ossewaarde, J M, Walboomers, J M, Van Den Brule, A J
OBJECTIVE--To investigate C trachomatis serovars in contact-traced heterosexual partners. METHODS--Urogenital Chlamydia trachomatis isolates (n = 112) derived from 35 heterosexual patients (index...