C. J. Price, L. Travé-massuyès, R. Milne, L. Ironi, B. Bredeweg, M. H. Lee, ...
This paper considers where the QR field might be in twenty years time, outlining five areas where developments in model-based systems in general, and qualitative reasoning in particular might have a...
DOI: 10.1017/S000000000000000 Printed in the United Kingdom Qualitative Futures (2008)
C. J. Price, L. Travé-massuyès, R. Milne, L. Ironi, K. Forbus, B. Bredeweg, ...
This paper reviews the state of the art in model-based systems and qualitative reasoning, and considers where the field will be in twenty years time. It highlights six areas where developments in...
From troubleshooting to process design: closing the manufacturing loop (2008)
C. J. Price, I. S. Pegler, M. B. Ratcliffe, A. Mcmanus, Ceredigion Sy Db
This paper describes the dual use of a case base for diagnosis and for improving the design of a manufacturing process. In the short term, the case base is used to provide past experience in dealing...
A direct search method for smooth and nonsmooth unconstrained optimization (2008)
Price, C.J., Reale, M., Robertson, B.L.
A derivative free frame based method for minimizing C¹ and non-smooth functions is described. A 'black-box' function is assumed with gradients being unavailable. The use of frames allows gradient...
The effect of prior visual information on recognition of speech and sounds (2008)
Noppeney, U., Josephs, O., Hocking, J., Price, C.J., Friston, K.J.
To identify and categorize complex stimuli such as familiar objects or speech, the human brain integrates information that is abstracted at multiple levels from its sensory inputs. Using cross-modal...
T. N. Phillips, C. J. Price, L. G. Moseley
Although the development of rheological software has kept pace with the advances in modern rheometrical instruments the process of data analysis and interpretation remains fallible and can be prone...
Centre for Intelligent Systems (2007)
This paper describes an industrial application of case-based reasoning (CBR) in the aluminium die-casting industry: the setting of parameters of a pressure diecasting machine for a specific die. As...
Towards the Characterization of Viscoelastic Materials Using Model-Based Reasoning Techniques (2007)
A rheological equation of state is required to simulate the behaviour of a viscoelastic material in many complicated industrial ow processes. The generation of such a model is not a straightforward...
Anatomical traces of vocabulary acquisition in the adolescent brain (2007)
Devlin, J.T., Shakeshaft, C., Stewart, L.H., Brennan, A., Glensman, J., ...
A surprising discovery in recent years is that the structure of the adult human brain changes when a new cognitive or motor skill is learned. This effect is seen as a change in local gray or white...
Noppeney, U., Patterson, K., Tyler, L.K., Moss, H., Stamatakis, E.A., Bright, P., ...
Both herpes simplex virus encephalitis (HSVE) and semantic dementia (SD) typically affect anterior temporal lobe structures. Using voxel-based morphometry (VBM), this study compared the structural...
Exact and approximate judgements of visual and auditory numerosity: an fMRI study (2006)
Piazza, M., Mechelli, A., Price, C.J., Butterworth, B.
Human adults can assess the number of objects in a set (numerosity) by approximate estimation or by exact counting. There is evidence suggesting that numerosity estimation depends on a dedicated...
Language control in the bilingual brain (2006)
Crinion, J., Turner, R., Grogan, A., Hanakawa, T., Noppeney, U., Devlin, J.T., ...
How does the bilingual brain distinguish and control which language is in use? Previous functional imaging experiments have not been able to answer this question because proficient bilinguals...
Language control in the bilingual brain (2006)
Crinion, J., Turner, R., Grogan, A., Hanakawa, T., Noppeney, U., Devlin, J.T., ...
How does the bilingual brain distinguish and control which language is in use? Previous functional imaging experiments have not been able to answer this question because proficient bilinguals...
How reading differs from object naming at the neuronal level (2006)
Price, C.J., McCrory, E., Noppeney, U., Mechelli, A., Moore, C.J., Biggio, N., ...
This paper uses whole brain functional neuroimaging in neurologically normal participants to explore how reading aloud differs from object naming in terms of neuronal implementation. In the first...
Identification of degenerate neuronal systems based on intersubject variability (2006)
Noppeney, U., Penny, W.D., Price, C.J., Flandin, G., Friston, K.J.
Group studies implicitly assume that all subjects activate one common system to sustain a particular cognitive task. Intersubject variability is generally treated as well-behaved and uninteresting...
Reading skills after left anterior temporal lobe resection: an fMRI study (2005)
Noppeney, U., Price, C.J., Duncan, J.S., Koepp, M.J.
Maintaining language functions after left hemisphere lesions has been associated with compensatory right hemisphere activation. It remains unclear whether recruitment of right hemisphere regions...
Neurolinguistics: structural plasticity in the bilingual brain (2004)
Mechelli, A., Crinion, J.T., Noppeney, U., O'Doherty, J., Ashburner, J., Frackowiak, R.S., ...
Humans have a unique ability to learn more than one language — a skill that is thought to be mediated by functional (rather than structural) plastic changes in the brain1. Here we show that...
Performance of various BFGS implementations with limited precision second-order information (2004)
Byatt, D., Coope, I. D., Price, C. J.
The BFGS formula is arguably the most well known and widely used update method for quasi-Newton algorithms. Some authors have claimed that updating approximate Hessian information via the BFGS...
Good, C.D., Lawrence, K., Thomas, N.S., Price, C.J., Ashburner, J., Friston, K.J., ...
The amygdala, which plays a critical role in emotional learning and social cognition, is structurally and functionally sexually dimorphic in humans. We used magnetic neuroimaging and molecular...
Comparing event-related and epoch analysis in blocked design fMRI (2003)
Mechelli, A., Henson, R.N., Price, C.J., Friston, K.J.
In this study we demonstrate that, even in blocked design fMRI, an event-related analysis may provide a more accurate model of the hemodynamic responses than an epoch-related analysis. This is...
Estimating efficiency a priori: a comparison of blocked and randomized designs (2003)
Mechelli, A., Price, C.J., Henson, R.N., Friston, K.J.
This technical note deals with a priori estimation of efficiency of functional magnetic resonance imaging (fMRI) designs. The efficiency of an estimator is a measure of how reliable it is and depends...
Comparing event-related and epoch analysis in blocked design fMRI (2003)
Mechelli, A., Henson, R. N. A., Price, C. J., Friston, K. J.
Comparing event-related and epoch analysis in blocked design fMRI (2003)
Mechelli, A., Henson, R. N. A., Price, C. J., Friston, K. J.
The response of left temporal cortex to sentences (2002)
The meaning of a sentence differs from the sum of the meanings of its constituents. Left anterior temporal cortex responds to sentences more strongly than to unconnected words. We hypothesized that...
Are subitizing and counting implemented as separate or functionally overlapping processes? (2002)
Piazza, M., Mechelli, A., Butterworth, B., Price, C.J.
Enumeration of small groups of four or fewer objects is very fast and accurate (often called "subitizing"), but gets slower and more error prone for more than four items ("counting"). Many theories...
Henson, R.N.A., Price, C.J., Rugg, M.D., Turner, R., Friston, K.J.
We introduce a new method for detecting differences in the latency of blood oxygenation level-dependent (BOLD) responses to brief events within the context of the General Linear Model. Using a...
C. J. Price, M. D. Rugg, R. Turner, K. J. Friston
We introduce a new method for detecting differences in the latency of blood oxygenation level-dependent (BOLD) responses to brief events within the context of the General Linear Model. Using a...
Cross-modal plasticity underpins language recovery after cochlear implantation (2001)
Price, C.J., Graham, J.M., Truy, E., Frackowiak, R.S.J.
Postlingually deaf subjects learn the meaning of sounds after cochlear implantation by forming new associations between sounds and their sources. Implants generate coarse frequency responses,...
Dynamic diaschisis: anatomically remote and context-sensitive human brain lesions (2001)
Price, C.J., Warburton, E.A., Moore, C.J., Frackowiak, R.S.J., Friston, K.J.
Functional neuroimaging was used to investigate how lesions to the Broca's area impair neuronal responses in remote undamaged cortical regions. Four patients with speech output problems, but...
Are there reading specific brain areas? A meta-analysis of PET data from 72 subjects (2001)
C.J.Price, C.J.Moore, J.Phillips, E.McCrory, J.T.Devlin, ...
Gorno-Tempini, M. L., Price, C. J.
Several functional imaging experiments have clearly established that the fusiform gyri are preferentially responsive to faces, whereas the parahippocampal/lingual gyri are more responsive to...
Dual-process model in semantic priming: functional imaging perspective (1999)
Mummery, C.J., Shallice, T., Price, C.J.
In this positron emission tomography study, we investigated the neural correlates of semantic priming, where response to a word is facilitated when preceded by a semantically related word. Nine...
Disrupted temporal lobe connections in semantic dementia (1999)
Patterson, K, Wise, R J, Price, C J, Hodges, J R
Semantic dementia refers to the variant of frontotemporal dementia in which there is progressive semantic deterioration and anomia in the face of relative preservation of other language and cognitive...
Disrupted temporal lobe connections in semantic dementia (1999)
Mummery, C. J., Patterson, K., Wise, R. J. S., Vandenbergh, R., Price, C. J., Hodges, J. R.
Semantic dementia refers to the variant of frontotemporal dementia in which there is progressive semantic deterioration and anomia in the face of relative preservation of other language and cognitive...
Brunswick, N., McCrory, E., Price, C. J., Frith, C. D., Frith, U.
Two groups of male university students who had been diagnosed as dyslexic when younger, and two groups of control subjects of similar age and IQ to the dyslexics, were scanned whilst reading aloud...
The neural systems sustaining face and proper-name processing (1998)
Price, C J, Josephs, O, Cappa, S F, Kapur, N, ...
This PET study has revealed the neural system involved in implicit face, proper-name and object name processing during an explicit visual 'same' versus 'different' matching task. Within the...
Neural basis of an inherited speech and language disorder. (1998)
Vargha-Khadem, F., Watkins, K.E., Price, C.J., Ashburner, J., Alcock, K. J., Connelly, A., ...
Function-directed Electrical Design Analysis (1998)
Functional labels provide a simple but very reusable way for defining the functionality of a system and for making use of that knowledge. Unlike more complex functional representation schemes, these...
Combining Functional and Structural Reasoning for Safety Analysis of Electrical Designs (1997)
C. J. Price, D. R. Pugh, N. Snooke, J. E. Hunt, M. S. Wilson
Increasing complexity of design in automotive electrical systems has been paralleled by increased demands for analysis of the safety and reliability aspects of those designs. Such demands can place a...
Automated Sneak Identification (1996)
Sneak circuit analysis is an important design analysis method for detecting unexpected interactions between different parts of an electrical circuit design. It demands a great deal of effort from an...
Hearing and saying: The functional neuro-anatomy of auditory word processing (1996)
Price, C. J., Price, C. J., Wise, R. J. S., Warburton, E. A., Moore, C. J., Howard, D., ...
The neural systems involved in hearing and repeating single words were investigated in a series of experiments using PET. Neuropsychological and psycholinguistic studies implicate the involvement of...
Demonstrating the Implicit Processing of Visually Presented Words and Pseudowords (1996)
Price, C. J., Wise, R. J. S., Frackowiak, R. S. J.
This study demonstrates that even when subjects are instructed to perform a nonlinguistic visual feature detection task, the mere presence of words or pseudowords in the visual field activates a...
Brain activity during reading The effects of exposure duration and task (1994)
Price, C. J., Wise, R. J. S., Watson, J. D. G., Patterson, K., Howard, D., Frackowiak, R. S. J.
Brain activity during reading tasks was investigated using PET. The aim was to account for differences in the results of two previous studies [those of Petersen et al. (Science 1990; 249: 1041–4)...
Price, C. J. (Christopher John)
Typescript (photocopy).
Neural basis of an inherited speech and language disorder
Vargha-Khadem, F., Watkins, K. E., Price, C. J., Ashburner, J., Alcock, K. J., Connelly, A., ...
Investigation of the three-generation KE family, half of whose members are affected by a pronounced verbal dyspraxia, has led to identification of their core deficit as one involving sequential...
1. Noradrenaline (1mm) and 5-hydroxytryptamine (1mm) stimulated the production of unesterified palmitate, oleate, stearate and arachidonate in nerve endings (synaptosomes) isolated from combined...
Brindle, N P, Holt, M R, Davies, J E, Price, C J, Critchley, D R
In mammalian cells vasodilator-stimulated phosphoprotein (VASP) is localized to focal adhesions and areas of dynamic membrane activity where it is thought to have a role in actinfilament assembly....
The developmental toxicity of boric acid in mice, rats, and rabbits.
Heindel, J J, Price, C J, Schwetz, B A
Boric acid (BA) is a naturally occurring agent used in manufacturing processes and numerous consumer products. Because of the potential for both industrial and consumer exposure to boron-containing...
Neural basis of an inherited speech and language disorder
Vargha-Khadem, F., Watkins, K. E., Price, C. J., Ashburner, J., Alcock, K. J., Connelly, A., ...
Investigation of the three-generation KE family, half of whose members are affected by a pronounced verbal dyspraxia, has led to identification of their core deficit as one involving sequential...
1. Noradrenaline (1mm) and 5-hydroxytryptamine (1mm) stimulated the production of unesterified palmitate, oleate, stearate and arachidonate in nerve endings (synaptosomes) isolated from combined...
Brindle, N P, Holt, M R, Davies, J E, Price, C J, Critchley, D R
In mammalian cells vasodilator-stimulated phosphoprotein (VASP) is localized to focal adhesions and areas of dynamic membrane activity where it is thought to have a role in actinfilament assembly....
The developmental toxicity of boric acid in mice, rats, and rabbits.
Heindel, J J, Price, C J, Schwetz, B A
Boric acid (BA) is a naturally occurring agent used in manufacturing processes and numerous consumer products. Because of the potential for both industrial and consumer exposure to boron-containing...
The temporal dynamics of reading: a PET study.
The temporal dynamics of evoked brain responses are normally characterized using electrophysiological techniques but the positron emission tomography study presented here revealed a temporal aspect...
Category differences in brain activation studies: where do they come from?
Gorno-Tempini, M L, Cipolotti, L, Price, C J
Differences in the neural processing of six categories of pictorial stimuli (maps, body parts, objects, animals, famous faces and colours) were investigated using positron emission tomography....
Mechelli, A, Humphreys, G W, Mayall, K, Olson, A, Price, C J
Previous studies have shown differential responses in the fusiform and lingual gyri during reading and suggested that the former is engaged in processing local features of visual stimuli and the...
Humphreys, G W, Riddoch, M J, Price, C J
Many models of object identification are bottom-up and serial in nature; processing at a first stage needs to be complete before it is passed on to a subsequent stage, and there is no top-down...
Changing meaning causes coupling changes within higher levels of the cortical hierarchy
Schofield, T. M., Iverson, P., Kiebel, S. J., Stephan, K. E., Kilner, J. M., Friston, K. J., ...
Processing of speech and nonspeech sounds occurs bilaterally within primary auditory cortex and surrounding regions of the superior temporal gyrus; however, the manner in which these regions interact...
Seghier, M.L., Lee, H.L., Schofield, T., Ellis, C.L., Price, C.J.
Cognitive models of reading predict that high frequency regular words can be read in more than one way. We investigated this hypothesis using functional MRI and covariance analysis in 43 healthy...
Gray and white matter changes associated with tool-use learning in macaque monkeys
Quallo, M. M., Price, C. J., Ueno, K., Asamizuya, T., Cheng, K., Lemon, R. N., ...
We used noninvasive MRI and voxel-based morphometry (VBM) to detect changes in brain structure in three adult Japanese macaques trained to use a rake to retrieve food rewards. Monkeys, who were naive...
Integrating Visual and Tactile Information in the Perirhinal Cortex
Holdstock, J. S., Hocking, J., Notley, P., Devlin, J. T., Price, C. J.
By virtue of its widespread afferent projections, perirhinal cortex is thought to bind polymodal information into abstract object-level representations. Consistent with this proposal, deficits in...