Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment.
Li, S C, Goto, N K, Williams, K A, Deber, C M
Proline is established as a potent breaker of both alpha-helical and beta-sheet structures in soluble (globular) proteins. Thus, the frequent occurrence of the Pro residue in the putative...
Deber, C M, Khan, A R, Li, Z, Joensson, C, Glibowicka, M, Wang, J
Val-->Ala mutations within the effective transmembrane segment of a model single-spanning membrane protein, the 50-residue major coat (gene VIII) protein of bacteriophage M13, are shown to have...
Hypothesis about the function of membrane-buried proline residues in transport proteins.
In a survey of the bilayer-spanning regions of integral membrane proteins, membrane-buried proline residues were found in nearly all transport proteins examined, whereas membrane-buried regions of...
Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles.
In the course of their biological function, peptide hormones must be transferred from an aqueous phase to the lipid-rich environment of their membrane-bound receptor proteins. We have investigated...
Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment.
Li, S C, Goto, N K, Williams, K A, Deber, C M
Proline is established as a potent breaker of both alpha-helical and beta-sheet structures in soluble (globular) proteins. Thus, the frequent occurrence of the Pro residue in the putative...
Deber, C M, Khan, A R, Li, Z, Joensson, C, Glibowicka, M, Wang, J
Val-->Ala mutations within the effective transmembrane segment of a model single-spanning membrane protein, the 50-residue major coat (gene VIII) protein of bacteriophage M13, are shown to have...
Hypothesis about the function of membrane-buried proline residues in transport proteins.
In a survey of the bilayer-spanning regions of integral membrane proteins, membrane-buried proline residues were found in nearly all transport proteins examined, whereas membrane-buried regions of...
Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles.
In the course of their biological function, peptide hormones must be transferred from an aqueous phase to the lipid-rich environment of their membrane-bound receptor proteins. We have investigated...