Parpia, T., Raab, G.M., Goldberg, D.J., Allardice, G.M., McMenamin, J., Whitelaw, J., ...
There is accumulating evidence from clinical trials and cohort studies that highly active antiretroviral combination therapy is effective at halting immunologic and clinical progression of human...
Parpia, T., Raab, G.M., Goldberg, D.J., Allardice, G.M., McMenamin, J., Whitelaw, J., ...
There is accumulating evidence from clinical trials and cohort studies that highly active antiretroviral combination therapy is effective at halting immunologic and clinical progression of human...
Taylor, M.A., Reilly, D., Llewellyn-Jones, R.H., McSharry, C., Aitchison, T.
OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series....
McSharry, C, Lewis, C, Cruickshank, G, Richardson, M D
The measurement of serum arabinitol in the diagnosis of systemic candidosis was evaluated using a gas-liquid chromatography technique in a cohort of at risk patients. The prevalence of seropositivity...
Upton, M.N., McConnachie, A., McSharry, C., Hart, C.L., Davey Smith, G., Gillis, C.R., ...
Objective: To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. Design: Two epidemiological surveys 20 years apart. Identical questions were asked about...
McSharry, C, Lewis, C, Cruickshank, G, Richardson, M D
The measurement of serum arabinitol in the diagnosis of systemic candidosis was evaluated using a gas-liquid chromatography technique in a cohort of at risk patients. The prevalence of seropositivity...
Taylor, M.A., Reilly, D., Llewellyn-Jones, R.H., McSharry, C., Aitchison, T.
OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series....
Upton, M.N., McConnachie, A., McSharry, C., Hart, C.L., Davey Smith, G., Gillis, C.R., ...
Objective: To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. Design: Two epidemiological surveys 20 years apart. Identical questions were asked about...
McSharry, C, Anderson, K, McKay, I C, Colloff, M J, Feyerabend, C, Wilson, R B, ...
Raised levels of serum IgE antibodies to prawn antigens were found in 15 of 26 seafood factory process workers with respiratory symptoms and in one of 26 case-matched asymptomatic controls (P <...
Skin testing and extrinsic allergic alveolitis.
McSharry, C, Banham, S W, Lynch, P P, Boyd, G
Skin testing with six common allergens, tuberculin and a sterile avian antigen preparation from pigeon serum was performed on 102 pigeon fanciers. The incidence of positive prick tests to common...
Takes your breath away – the immunology of allergic alveolitis
MCSHARRY, C, ANDERSON, K, BOURKE, S J, BOYD, G
Extrinsic allergic alveolitis (synonym: hypersensitivity pneumonitis) is caused by inhaling antigenic aerosols which induce hypersensitivity responses in susceptible individuals. It is an...
Banham, S W, McSharry, C, Lynch, P P, Boyd, G
In a large scale clinical survey of Scottish pigeon fanciers, 277 people completed a detailed questionnaire and provided a venous blood sample. There were 29 (10.4%) who fulfilled the clinical...
Discriminant analysis of symptom pattern and serum antibody titres in humidifier related disease.
McSharry, C, Anderson, K, Speekenbrink, A, Lewis, C, Boyd, G
BACKGROUND--The heterogeneous patterns of symptoms among factory workers exposed to aerosols from contaminated air humidifiers were analysed to assess the association between specific symptoms and...
Angus, R M, Davies, M L, Cowan, M D, McSharry, C, Thomson, N C
BACKGROUND--Allergic bronchopulmonary aspergillosis is a disease of asthmatic patients which may follow a protracted course and result in chronic lung damage such as central bronchiectasis. In asthma...
Effect of house dust mite avoidance measures on adult atopic asthma.
Dorward, A J, Colloff, M J, MacKay, N S, McSharry, C, Thomson, N C
Twenty one adult patients with asthma, with positive skin test responses to the European house dust mite, Dermatophagoides pteronyssinus, were randomly allocated to a control group or to a group...
Non-invasive markers of airway inflammation as predictors of oral steroid responsiveness in asthma
Little, S., Chalmers, G., MacLeod, K., McSharry, C., Thomson, N.
BACKGROUND—Sputum eosinophil counts and exhaled nitric oxide (NO) levels are increased in asthma and both measurements fall in response to corticosteroids. METHODS—Exhaled NO levels and sputum...
Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma
Chalmers, G, Macleod, K, Little, S, Thomson, L, McSharry, C, Thomson, N
Background: Although inhaled corticosteroids have an established role in the treatment of asthma, studies have tended to concentrate on non-smokers and little is known about the possible effect of...
Little, S, Sproule, M, Cowan, M, Macleod, K, Robertson, M, Love, J, ...
Background: In some patients chronic asthma results in irreversible airflow obstruction. High resolution computed tomography (HRCT) has been advocated for assessing the structural changes in the...
Viral subtype and heterosexual acquisition of HIV infections diagnosed in Scotland
Yirrell, D. L., Goldberg, D. J., Whitelaw, J., McSharry, C., Raeside, F., Codere, G.
OBJECTIVE: As at December 1998, 87% of the estimated 33 million people living with HIV throughout the world resided in Africa and South East Asia. In Scotland (and the United Kingdom), a major public...
Role of heat shock proteins in the pathogenesis of cystic fibrosis arthritis
Al-Shamma, M. R., McSharry, C., McLeod, K., McCruden, E. A., Stack, B. H.
BACKGROUND: Arthritis is a well recognised complication of cystic fibrosis. The cause of this arthritis is not yet clear but it is likely to be an immunological reaction to one of the many bacterial...
Endothelin-1 levels in induced sputum samples from asthmatic and normal subjects
Chalmers, G. W., Thomson, L., Macleod, K. J., Dagg, K. D., McGinn, B. J., McSharry, C., ...
BACKGROUND: Endothelin-1 (ET-1) is a potent bronchoconstrictor which may have a role in the pathogenesis of asthma. The levels of ET-1 in saliva, induced sputum, and plasma from asthmatic and...