Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe.
Goodwin, A, Wang, S W, Toda, T, Norbury, C, Hickson, I D
Topoisomerases catalyse changes in the topological state of DNA and are required for many aspects of DNA metabolism. While the functions of topoisomerases I and II in eukaryotes are well established,...
Gene activation properties of a mouse DNA sequence isolated by expression selection.
Von Hoyningen-Huene, V, Norbury, C, Griffiths, M, Fried, M
The MES-1 element was previously isolated from restricted total mouse cellular DNA by "expression selection"--the ability to reactivate expression of a test gene devoid of its 5' enhancer sequences....
Premature chromatin condensation upon accumulation of NIMA.
O'Connell, M J, Norbury, C, Nurse, P
The NIMA protein kinase of Aspergillus nidulans is required for the G2/M transition of the cell cycle. Mutants lacking NIMA arrest without morphological characteristics of mitosis, but they do...
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.
The p34cdc2 protein kinase is a conserved regulator of the eukaryotic cell cycle. Here we show that residues Thr14 and Tyr15 of mouse p34cdc2 become phosphorylated as mouse fibroblasts proceed...
Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe.
Goodwin, A, Wang, S W, Toda, T, Norbury, C, Hickson, I D
Topoisomerases catalyse changes in the topological state of DNA and are required for many aspects of DNA metabolism. While the functions of topoisomerases I and II in eukaryotes are well established,...
Gene activation properties of a mouse DNA sequence isolated by expression selection.
Von Hoyningen-Huene, V, Norbury, C, Griffiths, M, Fried, M
The MES-1 element was previously isolated from restricted total mouse cellular DNA by "expression selection"--the ability to reactivate expression of a test gene devoid of its 5' enhancer sequences....
Premature chromatin condensation upon accumulation of NIMA.
O'Connell, M J, Norbury, C, Nurse, P
The NIMA protein kinase of Aspergillus nidulans is required for the G2/M transition of the cell cycle. Mutants lacking NIMA arrest without morphological characteristics of mitosis, but they do...
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.
The p34cdc2 protein kinase is a conserved regulator of the eukaryotic cell cycle. Here we show that residues Thr14 and Tyr15 of mouse p34cdc2 become phosphorylated as mouse fibroblasts proceed...
Analysis of genetic and phenotypic heterogeneity in juvenile polyposis
Woodford-Richens, K, Bevan, S, Churchman, M, Dowling, B, Jones, D, Norbury, C, ...
BACKGROUND—Juvenile polyposis syndrome (JPS) is characterised by gastrointestinal (GI) hamartomatous polyposis and an increased risk of GI malignancy. Juvenile polyps also occur in the Cowden (CS),...