C. Pannecouque

Anti-HIV activity of some Mannich bases of isatin derivatives. (1998)

Pandeya, S, Sriram, D, Clercq, E, Pannecouque, C, Witvrouw, M

1,1,3-Trioxo-2H,4H-Thieno[3,4-e][1,2,4]Thiadiazine (TTD) Derivatives: a New Class of Nonnucleoside Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitors with Anti-HIV-1 Activity

Witvrouw, M., Arranz, M. E., Pannecouque, C., Declercq, R., Jonckheere, H., ...

We report the development of a new group of nonnucleoside reverse transcriptase inhibitors (NNRTIs). One of the most active congeners of this series of...

Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates†

Balzarini, J., Pannecouque, C., De Clercq, E., Aquaro, S., Egberink, H., ...

A novel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy)ethoxy...

SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.

Witvrouw, M, Balzarini, J, Pannecouque, C, Jhaumeer-Laulloo, S, Esté, J A, Schols, D, ...

From a series of macrocyclic diamides possessing the disulfide linkage, only SRR-SB3, a compound that complexes with zinc, was found to inhibit human immunodeficiency virus type 1 (HIV-1; strain...

Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NMRI mice.

Balzarini, J, Vahlenkamp, T, Egberink, H, Hartmann, K, Witvrouw, M, Pannecouque, C, ...

From a side-by-side comparative study, the acyclic nucleoside phosphonates (R)-9-(2-phosphonylmethoxypropyl)adenine [(R)-PMPA] and 9-(2-methylidene-3-phosphonomethoxypropyl)guanine (MDL 74,968)...

1,1,3-Trioxo-2H,4H-Thieno[3,4-e][1,2,4]Thiadiazine (TTD) Derivatives: a New Class of Nonnucleoside Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitors with Anti-HIV-1 Activity

Witvrouw, M., Arranz, M. E., Pannecouque, C., Declercq, R., Jonckheere, H., ...

We report the development of a new group of nonnucleoside reverse transcriptase inhibitors (NNRTIs). One of the most active congeners of this series of...

Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates†

Balzarini, J., Pannecouque, C., De Clercq, E., Aquaro, S., Egberink, H., ...

A novel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy)ethoxy...

SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus.

Witvrouw, M, Balzarini, J, Pannecouque, C, Jhaumeer-Laulloo, S, Esté, J A, Schols, D, ...

From a series of macrocyclic diamides possessing the disulfide linkage, only SRR-SB3, a compound that complexes with zinc, was found to inhibit human immunodeficiency virus type 1 (HIV-1; strain...

Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NMRI mice.

Balzarini, J, Vahlenkamp, T, Egberink, H, Hartmann, K, Witvrouw, M, Pannecouque, C, ...

From a side-by-side comparative study, the acyclic nucleoside phosphonates (R)-9-(2-phosphonylmethoxypropyl)adenine [(R)-PMPA] and 9-(2-methylidene-3-phosphonomethoxypropyl)guanine (MDL 74,968)...

Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors

Cullen, M.D., Cheung, Y.F., Houslay, M.D., Hartman, T.L., Watson, K.M., Buckheit, R.W., ...

The alkenyldiarylmethanes (ADAMs) are currently being investigated as non- nucleoside HIV- 1 reverse transcriptase inhibitors (NNRTIs) of potential value in the treatment of HIV infection and AIDS....