C. Plachez

Robos are required for the correct targeting of retinal ganglion cell axons in the visual pathway of the brain. (2008)

Plachez, C., Andrews, W., Liapi, A., Knoell, B., Drescher, U., Mankoo, B., ...

The transcription factor Nfix is essential for normal brain development (2008)

Campbell, C. E., Piper, M., Plachez, C., Yeh, Y. T., Baizer, J. S., Osinski, J. M., ...

Nuclear Factor I gene expression in the developing forebrain (2008)

Plachez, C., Lindwall, C., Sunn, N., Piper, M., Moldrich, R. X., Campbell, C. E., ...

Diffusion tensor magnetic resonance imaging and tract-tracing analysis of probst bundle structure in Netrin1- and DCC-deficient mice (2007)

Ren, T, Zhang, JY, Plachez, C, Mori, S, Richards, LJ

In many cases of callosal dysgenesis in both human patients and mouse models, misguided fibers from the cortex form abnormal bilateral, barrel-shaped structures known as Probst bundles. Because...

Imaging, anatomical, and molecular analysis of callosal formation in the developing human fetal brain (2006)

Ren, T. B., Anderson, A., Shen, W. B., Huang, H., Plachez, C., Zhang, J. Y., ...

A complex set of axonal guidance mechanisms are utilized by axons to locate and innervate their targets. In the developing mouse forebrain, we previously described several midline glial populations...

Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain (2006)

Andrews, W., Liapi, A., Plachez, C., Camurri, L., Zhang, J. Y., Mori, S., ...

The Slit genes encode secreted ligands that regulate axon branching, commissural axon pathfinding and neuronal migration. The principal identified receptor for Slit is Robo ( Roundabout in...

Mapping postnatal mouse brain development with diffusion tensor microimaging (2005)

Zhang, J. Y., Miller, M. I., Plachez, C., Richards, L. J., Yarowsky, P., Van Zijl, P., ...

While mouse brain development has been extensively studied using histology, quantitative characterization of morphological changes is still a challenging task. This paper presents how developing...

Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis (2005)

Zhang, J. Y., Chen, Y. B., Hardwick, J. M., Miller, M. I., Plachez, C., Richards, L. J., ...

A new technique based on diffusion tensor imaging and computational neuroanatomy was developed to efficiently and quantitatively characterize the three- dimensional morphology of the developing...

Mechanisms of axon guidance in the developing nervous system (2005)

Plachez, C., Richards, L. J.

The human brain assembles an incredible network of over a billion neurons. Understanding how these connections form during development in order for the brain to function properly is a fundamental...

The transcription factor gene Nfib is essential for both lung maturation and brain development (2005)

Steele-Perkins, G., Plachez, C., Butz, K. G., Yang, G. H., Bachurski, C. J., Kinsman, S. L., ...

The phylogenetically conserved nuclear factor I (NFI) gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that...

Mechanisms regulating the development of the corpus callosum and its agenesis in mouse and human (2004)

Richards, L. J., Plachez, C., Ren, T.

The development of the corpus callosum depends on a large number of different cellular and molecular mechanisms. These include the formation of midline glial populations, and the expression of...

Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice (2003)

Shu, T. Z., Butz, K. G., Plachez, C., Gronostajski, R. M., Richards, L. J.

Nuclear factor I (NFI) genes are expressed in multiple organs throughout development (Chaudhry et al., 1997; for review, see Gronostajski, 2000). All four NFI genes are expressed in embryonic mouse...