C. R. H.

An asymmetric C8/C8’-tripyrrole-linked sequence selective pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer DNA interstrand cross-linking agent spanning 11 DNA base pairs (2008)

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A 96-well DNase I footprinting screen for drug–DNA interactions (2007)

C.R.H., ...

The established protocol for DNase I footprinting has been modified to allow multiple parallel reactions to be rapidly performed in 96-well microtitre plates. By scrutinizing every aspect of the...

Design, synthesis, and biophysical and biological evaluation of a series of Pyrrolobenzodiazepine - Poly(N-methylpyrrole) conjugates (2006)

C.R.H., ...