C. Specker

Ankylosing spondylitis: an autoimmune disease?

Lakomek, H J, Plomann, M, Specker, C, Schwochau, M

Identification of several autoantibodies in serum samples from patients with ankylosing spondylitis or suspected ankylosing spondylitis is reported. Five antibodies associated with ankylosing...

Novel 68 kDa autoantigen detected by rheumatoid arthritis specific antibodies.

Bläss, S, Specker, C, Lakomek, H J, Schneider, E M, Schwochau, M

OBJECTIVE--To improve the understanding of the pathogenesis of rheumatoid arthritis (RA) by identifying novel, disease specific autoantibodies. METHODS--Total protein preparations from synovial...

Rheumatoid arthritis: autoreactive T cells recognising a novel 68k autoantigen

Bla{beta}, S., Haferkamp, C, Specker, C., Schwochau, M, Schneider, M, Schneider, E

OBJECTIVE—A 68k autoantigen has been identified by specific antibodies from patients with rheumatoid arthritis (RA). This study considered whether or not this antigen is a target for T cells and...

The p68 autoantigen characteristic of rheumatoid arthritis is reactive with carbohydrate epitope specific autoantibodies

Meier, C., Vohr, H, Schwochau, M, Specker, C., Burmester, G

OBJECTIVE—The autoantigen p68 is a target of autoantibodies as well as autoreactive T cells with a high specificity in rheumatoid arthritis (RA). The binding characteristics of the autoantibodies...

CD134 expression on CD4+ T cells is associated with nephritis and disease activity in patients with systemic lupus erythematosus

Patschan, S, Dolff, S, Kribben, A, Dürig, J, Patschan, D, Wilde, B, ...

Systemic lupus erythematosus (SLE) is characterized by a deviation of the immune system that involves T cell-dependent autoantibody production. The aim of this study was to investigate the role of...