Scientific Commons: C. Vearing

Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: Potential as EphA3-specific tumor-targeting reagents (2005)

Vearing, C, Lee, FT, Wimmer-Kleikamp, S, Spirkoska, V, To, C, Stylianou, C, ...

The Eph receptor tyrosine kinases and their membrane-bound ephrin ligands form a unique cell-cell contact-mediated system for controlling cell localization and organization. Their high expression in...

Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: Potential as EphA3-specific tumor-targeting reagents (2005)

Vearing, C, Lee, FT, Wimmer-Kleikamp, S, Spirkoska, V, To, C, Stylianou, C, ...

The Eph receptor tyrosine kinases and their membrane-bound ephrin ligands form a unique cell-cell contact-mediated system for controlling cell localization and organization. Their high expression in...

Dissecting the EphA3/ephrin-A5 interactions using a novel functional mutagenesis screen (2004)

Smith, F. M., Vearing, C., Lackmann, M., Treutlein, H., Himanen, J., Chen, K., ...

The EphA3 receptor tyrosine kinase preferentially binds ephrin-A5, a member of the corresponding subfamily of membrane-associated ligands. Their interaction regulates critical cell communication...

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling (2004)

Himanen, JP, Chumley, MJ, Lackmann, M, Li, C, Barton, WA, Jeffrey, PD, ...

The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A...