Chari, Raj, Coe, Bradley P, Wedseltoft, Craig, Benetti, Marie, Wilson, Ian M, Vucic, Emily A, ...
Abstract Background High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packages to...
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data (2008)
Chi, Bryan, DeLeeuw, Ronald J, Coe, Bradley P, Ng, Raymond T, MacAulay, Calum, Lam, Wan L
Abstract Background Recent advances in global genomic profiling methodologies have enabled multi-dimensional characterization of biological systems. Complete analysis of these genomic profiles...
Shadeo, Ashleen, Chari, Raj, Lonergan, Kim M, Pusic, Andrea, Miller, Dianne, Ehlen, Tom, ...
Abstract Background The highest rates of cervical cancer are found in developing countries. Frontline monitoring has reduced these rates in developed countries and present day screening programs...
Disruption of the Non-Canonical WNT Pathway in Lung Squamous Cell Carcinoma (2008)
Raj Chari, Andy Lam, Raymond T. Ng, John Yee, John English, ...
Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway. In this study, we investigate the...
Disruption of the Non-Canonical WNT Pathway in Lung Squamous Cell Carcinoma (2008)
Raj Chari, Andy Lam, Raymond T. Ng, John Yee, John English, ...
Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway. In this study, we investigate the...
SIGMA2: A system for the integrative genomic multi-dimensional (2008)
Bmc Bioinformatics, Raj Chari, Bradley P Coe, Craig Wedseltoft, Marie Benetti, Emily A Vucic, ...
Software
Oral Cancer Screening in a High-Risk Underserved Community: Vancouver Downtown Eastside (2007)
Poh, Catherine F., Hislop, Gregory., Currie, Brenda., Lee, Rick., Sikorski, Sean., Zed, Chris., ...
Journal of Health Care for the Poor and Underserved - Volume 18, Number 4, November 2007
Effect of active smoking on the human bronchial epithelium transcriptome (2007)
Chari, Raj, Lonergan, Kim M, Ng, Raymond T, MacAulay, Calum, Lam, Wan L, Lam, Stephen
Abstract Background Lung cancer is the most common cause of cancer-related deaths. Tobacco smoke exposure is the strongest aetiological factor associated with lung cancer. In this study, using serial...
Comprehensive serial analysis of gene expression of the cervical transcriptome (2007)
Shadeo, Ashleen, Chari, Raj, Vatcher, Greg, Campbell, Jennifer, Lonergan, Kim M, Matisic, Jasenka, ...
Abstract Background More than half of the approximately 500,000 women diagnosed with cervical cancer worldwide each year will die from this disease. Investigation of genes expressed in precancer...
Julie M. Kneller, Thomas Ehlen, Jasenka P. Matisic, Dianne Miller, Dirk Van Niekerk, Wan L. Lam, ...
Sixteen longSAGE libraries from four different clinical stages of cervical intraepithelial neoplasia have enabled us to identify novel cell-surface biomarkers indicative of CIN stage. By comparing...
Bmc Genomics, Raj Chari, Kim M Lonergan, Raymond T Ng, Calum Macaulay, Wan L Lam, ...
Research article Effect of active smoking on the human bronchial epithelium transcriptome
SIGMA: A System for Integrative Genomic Microarray Analysis of Cancer Genomes (2006)
Chari, Raj, Lockwood, William W, Coe, Bradley P, Chu, Anna, Macey, Devon, Thomson, Andrew, ...
Abstract Background The prevalence of high resolution profiling of genomes has created a need for the integrative analysis of information generated from multiple methodologies and platforms. Although...
Bmc Genomics, Raj Chari, William W Lockwood, Bradley P Coe, Anna Chu, Devon Macey, ...
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
A stepwise framework for the normalization of array CGH data (2005)
Khojasteh, Mehrnoush, Lam, Wan L, Ward, Rabab K, MacAulay, Calum
Abstract Background In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly used to...
Mehrnoush Khojasteh, Wan L Lam, Rabab K Ward, Calum Macaulay, Biomed Central, Calum Macaulay
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2005)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak presumably...
Chi, Bryan, DeLeeuw, Ronald J, Coe, Bradley P, MacAulay, Calum, Lam, Wan L
Abstract Background Array comparative genomic hybridization (CGH) is a technique which detects copy number differences in DNA segments. Complete sequencing of the human genome and the development of...
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2004)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in the North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak...
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2004)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in the North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak...
Haishan Zeng, Mladen Korbelik, David I. McLean, Calum MacAulay, Harvey Lui
In current clinical practice, photodynamic therapy (PDT) is carried out with prescribed drug doses and light doses as well as fixed drug–light intervals and illumination fluence rates. This...
A Randomized Phase IIb Trial of Anethole Dithiolethione in Smokers with Bronchial Dysplasia (2002)
Lam, Stephen, MacAulay, Calum, Le Riche, Jean C., Dyachkova, Yulia, Coldman, Andy, Guillaud, Martial, ...
Background: Results from preclinical studies have suggested that the organosulfur compound anethole dithiolethione (ADT) may be an effective chemopreventive agent for lung cancer. We conducted a...
Sex-Related Differences in Bronchial Epithelial Changes Associated With Tobacco Smoking (1999)
Lam, Stephen, LeRiche, Jean C., Zheng, Yvonne, Coldman, Andrew, MacAulay, Calum, Hawk, Ernest, ...
BACKGROUND: Lung cancer is the most common cause of cancer death in North American women. Because smoking-related changes in the bronchial epithelium and in lung function have not been studied in...
A stepwise framework for the normalization of array CGH data
Khojasteh, Mehrnoush, Lam, Wan L, Ward, Rabab K, MacAulay, Calum
A stepwise framework for the normalization of array CGH data
Khojasteh, Mehrnoush, Lam, Wan L, Ward, Rabab K, MacAulay, Calum
SIGMA: A System for Integrative Genomic Microarray Analysis of Cancer Genomes
Chari, Raj, Lockwood, William W, Coe, Bradley P, Chu, Anna, Macey, Devon, Thomson, Andrew, ...
Comprehensive serial analysis of gene expression of the cervical transcriptome
Shadeo, Ashleen, Chari, Raj, Vatcher, Greg, Campbell, Jennifer, Lonergan, Kim M, Matisic, Jasenka, ...
A Comprehensive Analysis of Common Copy-Number Variations in the Human Genome
Wong, Kendy K., DeLeeuw, Ronald J., Dosanjh, Nirpjit S., Kimm, Lindsey R., Cheng, Ze, Horsman, Douglas E., ...
Segmental copy-number variations (CNVs) in the human genome are associated with developmental disorders and susceptibility to diseases. More importantly, CNVs may represent a major genetic component...
Effect of active smoking on the human bronchial epithelium transcriptome
Chari, Raj, Lonergan, Kim M, Ng, Raymond T, MacAulay, Calum, Lam, Wan L, Lam, Stephen
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
Chi, Bryan, DeLeeuw, Ronald J, Coe, Bradley P, Ng, Raymond T, MacAulay, Calum, Lam, Wan L
Kneller, Julie M., Ehlen, Thomas, Matisic, Jasenka P., Miller, Dianne, Van Niekerk, Dirk, Lam, Wan L., ...
Sixteen longSAGE libraries from four different clinical stages of cervical intraepithelial neoplasia have enabled us to identify novel cell-surface biomarkers indicative of CIN stage. By comparing...