Carl G. A. Persson

Nasal neutrophil activity and mucinous secretory responsiveness in COPD. (2003)

Nihlén, Ulf, Andersson, Morgan, Löfdahl, Claes-Göran, Persson, Carl G A, Montnémery, Peter, Greiff, Lennart

Patients with chronic obstructive pulmonary disease (COPD) frequently report nasal symptoms. In the present study, we have examined whether or not COPD is associated with any nasal inflammation....

Neural Expression and Increased Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Secretoneurin is a neuropeptide potentially involved in migration of eosinophils, monocytes, and dendritic cells. Whether secretoneurin is present in the human airway mucosa and whether it is...

Absorption across the nasal airway mucosa in house dust mite perennial allergic rhinitis. (2002)

Greiff, Lennart, Andersson, Morgan, Svensson, Jenny, Wollmer, Per, Lundin, Stefan, Persson, Carl G A

House dust mite allergens express protease activity and it has been suggested that this property has pathogenic effects by increasing airway absorption. In accordance, house dust mite allergens may...

Loss of size-selectivity at histamine-induced exudation of plasma proteins in atopic nasal airways. (2002)

Greiff, Lennart, Andersson, Morgan, Erjefält, Jonas S, Svensson, Christer, Persson, Carl G A

Plasma proteins occur in the airway lumen in inflammatory airway diseases. This study tests the hypothesis that airway microvascular-epithelial exudation of plasma proteins, as induced by a...

Desloratadine reduces allergen challenge-induced mucinous secretion and plasma exudation in allergic rhinitis. (2002)

Greiff, Lennart, Persson, Carl G A, Andersson, Morgan

BACKGROUND: Rhinorrhea is a key symptom of allergic rhinitis and this disease feature is reduced by antihistamine treatment. The nasal output of fluid in allergic rhinitis is associated with luminal...

Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice

Korsgren, Magnus, Persson, Carl G.A., Sundler, Frank, Bjerke, Torbjörn, Hansson, Tony, Chambers, Benedict J., ...

The earliest contact between antigen and the innate immune system is thought to direct the subsequent antigen-specific T cell response. We hypothesized that cells of the innate immune system, such as...

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

Korsgren, Magnus, ält, Jonas S. Erjef, Korsgren, Olle, Sundler, Frank, Persson, Carl G.A.

Immunoglobulins (Ig), particularly IgE, are believed to be crucially involved in the pathogenesis of asthma and, equally, in allergic models of the disease. To validate this paradigm we examined...