Carla Oliveira

A comparative study of recombinant and native frutalin binding to human prostate tissues (2009)

Oliveira, Carla, Teixeira, José A, Schmitt, Fernando, Domingues, Lucília

Abstract Background Numerous studies indicate that cancer cells present an aberrant glycosylation pattern that can be detected by lectin histochemistry. Lectins have shown the ability to recognise...

Germline CDH1 deletions in hereditary diffuse gastric cancer families (2009)

Oliveira, Carla, Senz, Janine, Kaurah, Pardeep, Pinheiro, Hugo, Sanges, Remo, Haegert, Anne, ...

Germline CDH1 point or small frameshift mutations can be identified in 30–50% of hereditary diffuse gastric cancer (HDGC) families. We hypothesized that CDH1 genomic rearrangements would be found...

BRAF, KRASand PIK3CAmutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis? (2008)

Velho, Sérgia, Moutinho, Cátia, Cirnes, Luís, Albuquerque, Cristina, Hamelin, Richard, Schmitt, Fernando, ...

Abstract Background BRAF , KRAS and PIK3CA mutations are frequently found in sporadic colorectal cancer (CRC). In contrast to KRAS and PIK3CA mutations, BRAF mutations are associated with tumours...

Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer (2008)

Simões-Correia, Joana, Figueiredo, Joana, Oliveira, Carla, Van Hengel, Jolanda, Seruca, Raquel, Van Roy, Frans, ...

E-cadherin is critical for the maintenance of tissue architecture and is a major component of adherens junctions. Its role in tumour development is well established, with many human carcinomas...

Ansiedade de separação materna e adaptação psicossocial ao pré-escolar (2006)

Manuela Veríssimo, Sara Alves, Lígia Monteiro, Carla Oliveira

Ansiedade de separação materna e adaptação psicossocial ao pré-escolar

E-cadherin missense mutations, associated with Hereditary Diffuse Gastric Cancer (HDGC) syndrome, display distinct invasive behaviours and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia (2006)

Pereira, Paulo, Teixeira, Alexandra, Pinho, Sofia, Ferreira, Paulo, Fernandes, Joana, Oliveira, Carla, ...

Germline mutations in the human E-Cadherin gene, CDH1, are initiating events in cases of human hereditary diffuse gastric cancer (HDGC) indicating that hE-cadherin (hEcad) is a tumor suppressor....

E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia (2006)

Pereira, Paulo S., Teixeira, Alexandra, Pinho, Sofia, Ferreira, Paulo, Fernandes, Joana, Oliveira, Carla, ...

Germline mutations in the human E-cadherin (hEcad) gene, CDH1, are initiating events in cases of human hereditary diffuse gastric cancer (HDGC) indicating that hEcad is a tumor suppressor. Among the...

Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer (2005)

Gorringe, Kylie L., Chin, Suet-Feung, Pharoah, Paul, Staines, Joanne M., Oliveira, Carla, Edwards, Paul A. W., ...

Cancer cells contain many genetic alterations, and genetic instability may be important in tumourigenesis. We evaluated 58 breast and ovarian cancer cell lines for microsatellite instability (MSI)...

Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer (2005)

Gorringe, Kylie L., Chin, Suet-Feung, Pharoah, Paul, Staines, Joanne M., Oliveira, Carla, Edwards, Paul A.W., ...

Cancer cells contain many genetic alterations, and genetic instability may be important in tumourigenesis. We evaluated 58 breast and ovarian cancer cell lines for microsatellite instability (MSI)...

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline Mismatch Repair defects and hMLH1 methylation status (2004)

Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...

In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status (2004)

Oliveira, Carla, Westra, Jantine L., Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...

In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from hereditary non-polyposis colorectal cancer...

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline Mismatch Repair defects and hMLH1 methylation status (2004)

Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...

In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...

E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells (2003)

Suriano, Gianpaolo, Oliveira, Maria José, Huntsman, David, Mateus, Ana Rita, Ferreira, Paulo, Casares, Fernando, ...

In Hereditary Diffuse Gastric Cancer syndrome E-cadherin germline mutations of the missense type harbour significant functional consequences. In this study, we have characterised the effect of T340A,...

Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands (2003)

Suriano, Gianpaolo, Oliveira, Carla, Ferreira, Paulo, Machado, José C., Bordin, Maria C., De Wever, Olivier, ...

E-cadherin is involved in the formation of cell-junctions and the maintenance of epithelial integrity. Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of...

E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells (2003)

Suriano, Gianpaolo, Oliveira, Maria José, Huntsman, David, Mateus, Ana Rita, Ferreira, Paulo, Casares, Fernando, ...

In Hereditary Diffuse Gastric Cancer syndrome, E-cadherin germline mutations of the missense type harbour significant functional consequences. In this study, we have characterised the effect of...

E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells (2003)

Suriano, Gianpaolo, Oliveira, Maria José, Huntsman, David, Mateus, Ana Rita, Ferreira, Paulo, Casares, Fernando, ...

In Hereditary Diffuse Gastric Cancer syndrome E-cadherin germline mutations of the missense type harbour significant functional consequences. In this study, we have characterised the effect of T340A,...

The Clinicopathological Features of Gastric Carcinomas with Microsatellite Instability May Be Mediated by Mutations of Different “Target Genes” : A Study of the TGFβ RII, IGFII R, and BAX Genes

Oliveira, Carla, Seruca, Raquel, Seixas, Mário, Sobrinho-Simões, Manuel

Gastric carcinomas with DNA replication errors (RER phenotype) display a particular clinicopathologic profile and carry a putative favorable prognosis. The RER phenotype has been identified as...

Multiple objective linear programming models with interval coefficients - an illustrated overview

Oliveira, Carla, Antunes, Carlos Henggeler

A multiple objective model to deal with economy-energy-environment interactions

Oliveira, Carla, Antunes, Carlos Henggeler

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis?

Velho, Sérgia, Moutinho, Cátia, Cirnes, Luís, Albuquerque, Cristina, Hamelin, Richard, Schmitt, Fernando, ...

Germline CDH1 deletions in hereditary diffuse gastric cancer families

Oliveira, Carla, Senz, Janine, Kaurah, Pardeep, Pinheiro, Hugo, Sanges, Remo, Haegert, Anne, ...

Germline CDH1 point or small frameshift mutations can be identified in 30–50% of hereditary diffuse gastric cancer (HDGC) families. We hypothesized that CDH1 genomic rearrangements would be found...

A comparative study of recombinant and native frutalin binding to human prostate tissues

Oliveira, Carla, Teixeira, José A, Schmitt, Fernando, Domingues, Lucília