Carla Oseroff

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses? (2009)

Kotturi, Maya F, Assarsson, Erika, Peters, Bjoern, Grey, Howard, Oseroff, Carla, Pasquetto, Valerie, ...

Abstract Background Previous studies have defined vaccinia virus (VACV)-derived T cell epitopes in VACV-infected human leukocyte antigen-A*0201 (HLA-A2.1) transgenic (Tg) mice and A2.1-positive human...

High affinity for class II molecules as a necessary but not sufficient characteristic of encephalitogenic determinants (1992)

Wall, Mellssa, Southwood, Scott, Sidney, John, Oseroff, Carla, Guericio, Marie-France Del, Lamont, Alan G., ...

A direct binding assay specific for IAs molecules has been developed and Its immunological relevance validated by examining, for a panel of nine different synthetic peptides, the correlation between...

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...

We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...

We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...

The CD8+ T-Cell Response to Lymphocytic Choriomeningitis Virus Involves the L Antigen: Uncovering New Tricks for an Old Virus▿ †

Kotturi, Maya F., Peters, Bjoern, Buendia-Laysa, Fernando, Sidney, John, Oseroff, Carla, Botten, Jason, ...

CD8+ T-cell responses control lymphocytic choriomeningitis virus (LCMV) infection in H-2b mice. Although antigen-specific responses against LCMV infection are well studied, we found that a...

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

Assarsson, Erika, Greenbaum, Jason A., Sundström, Magnus, Schaffer, Lana, Hammond, Jennifer A., Pasquetto, Valerie, ...

Vaccinia virus is the prototypic orthopoxvirus and was the vaccine used to eradicate smallpox, yet the expression profiles of many of its genes remain unknown. Using a genome tiling array approach,...

Reply to Satheshkumar and Moss: Poxvirus transcriptome analysis

Assarsson, Erika, Greenbaum, Jason A., Sundström, Magnus, Schaffer, Lana, Hammond, Jennifer A., Pasquetto, Valerie, ...

Lymphocytic Choriomeningitis Virus Infection Yields Overlapping CD4+ and CD8+ T-Cell Responses▿

Dow, Courtney, Oseroff, Carla, Peters, Bjoern, Nance-Sotelo, Courtney, Sidney, John, Buchmeier, Michael, ...

Activation of CD4+ T cells helps establish and sustain other immune responses. We have previously shown that responses against a broad set of nine CD4+ T-cell epitopes were present in the setting of...

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans ▿ † ‡

Assarsson, Erika, Bui, Huynh-Hoa, Sidney, John, Zhang, Qing, Glenn, Jean, Oseroff, Carla, ...

Continuing antigenic drift allows influenza viruses to escape antibody-mediated recognition, and as a consequence, the vaccine currently in use needs to be altered annually. Highly conserved epitopes...

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?

Kotturi, Maya F, Assarsson, Erika, Peters, Bjoern, Grey, Howard, Oseroff, Carla, Pasquetto, Valerie, ...