Herrera, Emilio A., Reyes, Roberto V., Giussani, Dino A., Riquelme, Raquel A., Sanhueza, Emilia M., Ebensperger, Germán, ...
Aims To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas. Methods and results We used neonatal...
Evolving in thin air: lessons from the llama fetus in the altiplano (2007)
Llanos, Aníbal J., Riquelme, Raquel A., Herrera, Emilio A., Ebensperger, Germán, Krause, Bernardo, Reyes, Roberto V., ...
Compared with lowland species, fetal life for mammalian species whose mothers live in high altitude is demanding. For instance, fetal llamas have to cope with the low fetal arterial PO2 of all...
Herrera, Emilio A., Pulgar, Victor M., Riquelme, Raquel A., Sanhueza, Emilia M., Reyes, Roberto V., Ebensperger, German, ...
Perinatal exposure to chronic hypoxia induces sustained pulmonary hypertension and structural and functional changes in both pulmonary and systemic vascular beds. The aim of this study was to analyze...
Herrera, Emilio A., Pulgar, Víctor M., Riquelme, Raquel A., Sanhueza, Emilia M., Reyes, Roberto V., Ebensperger, Germán, ...
Perinatal exposure to chronic hypoxia induces sustained pulmonary hypertension and structural and functional changes in both pulmonary and systemic vascular beds. The aim of this study was to analyze...
Herrera, Emilio A., Reyes, Roberto V., Giussani, Dino A., Riquelme, Raquel A., Sanhueza, Emilia M., Ebensperger, Germán, ...
Aims To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas. Methods and results We used neonatal...
Herrera, Emilio A., Reyes, Roberto V., Giussani, Dino A., Riquelme, Raquel A., Sanhueza, Emilia M., Ebensperger, Germán, ...
Aims To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas. Methods and results We used neonatal...
Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia (2005)
Sanhueza, Emilia M., Riquelme, Raquel, Herrera, Emilio A., Giussani, Dino A., Blanco, Carlos E., Hanson, Mark A., ...
The fetal llama responds to hypoxemia, with a marked peripheral vasoconstriction but, unlike the sheep, with little or no increase in cerebral blood flow. We tested the hypothesis that the role of...
The fetal llama versus the fetal sheep: different strategies to withstand hypoxia (2003)
Llanos, Anibal J., Riquelme, Raquel A., Sanhueza, Emilia M., Hanson, Mark A., Blanco, Carlos E., Parer, Julian T., ...
The pregnant llama (Lama glama) has walked for millions of years through the thin oxygen trail of the Andean altiplano. We hypothesize that a pool of genes has been selected in the llama that express...
Riquelme, Raquel A., Sánchez, Gina, Liberona, Leonal, Sanhueza, Emilia M., Giussani, Dino A., Blanco, Carlos E., ...
The hypothesis that nitric oxide plays a key role in the regulation of adrenal blood flow and plasma concentrations of cortisol and catecholamines under basal and hypoxaemic conditions in the llama...
Effects of chronic hypoxia and protein malnutrition on growth in the developing chick (2002)
Miller, Suzanne L., Green, Lucy R., Peebles, Donald M., Hanson, Mark A., Blanco, Carlos E.
Objective: the purpose of this study was to determine how chronic hypoxia and/or protein malnutrition in ovo affect growth in developing chicks. Study Design: chicken eggs were incubated under...
Cardiac output distribution in the chick embryo from stage 36 to 45 (1997)
Mulder, Twan L.M., C. Van Golde, Jolanda, Prinzen, Frits W., Blanco, Carlos E.
Objective: The distribution of cardiac output to different organs is well described in the mammalian fetus. Chick embryos are not often used in perinatal cardiovascular research and therefore it is...
Baroreceptor reflex sensitivity in human neonates: the effect of postmenstrual age
Andriessen, Peter, Oetomo, Sidarto Bambang, Peters, Chris, Vermeulen, Barbara, Wijn, Pieter FF, Blanco, Carlos E
We performed a cross-sectional study in human infants to determine if indices of R–R interval variability, systolic blood pressure (SBP) variability, and baroreceptor reflex sensitivity change with...
Baroreceptor reflex sensitivity in human neonates: the effect of postmenstrual age
Andriessen, Peter, Oetomo, Sidarto Bambang, Peters, Chris, Vermeulen, Barbara, Wijn, Pieter FF, Blanco, Carlos E
We performed a cross-sectional study in human infants to determine if indices of R–R interval variability, systolic blood pressure (SBP) variability, and baroreceptor reflex sensitivity change with...
Induction of antioxidant enzyme activity by hyperoxia (60 % O2) in the developing chick embryo
Van Golde, Jolanda C, Borm, Paul J, Wolfs, Marion C, Rhijnsburger, Els H, Blanco, Carlos E
At premature birth, man and animals are exposed to relatively high oxygen levels, compared with intra-uterine conditions, at a time when their antioxidant enzyme (AOE) system is still immature. Using...
Hyperoxia and local organ blood flow in the developing chick embryo
Scheve, Esther, Prinzen, Frits W, Blanco, Carlos E
Hyperoxia can cause local vasoconstriction in adult animal organs as a protective mechanism against hyperoxia-induced toxicity. It is not known at what time during development this vasoconstrictor...
Riquelme, Raquel A, Sánchez, Gina, Liberona, Leonel, Sanhueza, Emilia M, Giussani, Dino A, Blanco, Carlos E, ...
The hypothesis that nitric oxide plays a key role in the regulation of adrenal blood flow and plasma concentrations of cortisol and catecholamines under basal and hypoxaemic conditions in the llama...
Scheepens, Arjan, Van De Waarenburg, Marjo, Van Den Hove, Daniël, Blanco, Carlos E
The aim of this study was to determine the effects of a clinically relevant single course of prenatal betamethasone in the rat on growth parameters with particular reference to brain cell...
The role of oxygen in prenatal growth: studies in the chick embryo
Giussani, Dino A, Salinas, Carlos E, Villena, Mercedes, Blanco, Carlos E
The compelling evidence linking small size at birth with later cardiovascular disease has renewed and amplified scientific and clinical interests into the determinants of fetal growth. It is accepted...