Rusniok, Christophe, Vallenet, David, Floquet, Stéphanie, Ewles, Helen, Mouzé-Soulama, Coralie, Brown, Daniel, ...
Abstract Background Genome sequences, now available for most pathogens, hold promise for the rational design of new therapies. However, biological resources for genome-scale identification of gene...
Le Roux, Frederique, Zouine, Mohamed, Chakroun, Nesrine, Binesse, Johan, SAULNIER, Denis, Bouchier, Christiane, ...
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Microbiology (1999), 145, 2625–2634 Printed in Great Britain REVIEW ARTICLE Overview (2009)
Lionel Frangeul, Karen E. Nelson, Carmen Buchrieser, Antoine Danchin, Frank Kunst
The knowledge of an entire genome sequence not only provides a wealth of data, but also specific information that can not be obtained by other approaches. Only after...
Pathogenomics: An updated European Research Agenda (2008)
Demuth, Andreas, Aharonowitz, Yair, Bachmann, Till T., Blum-Oehler, Gabriele, Buchrieser, Carmen, Covacci, Antonello, ...
Cazalet, Christel, Jarraud, Sophie, Ghavi-Helm, Yad, Kunst, Frank, Glaser, Philippe, Etienne, Jerome, ...
Genomics can provide the basis for understanding the evolution of emerging, lethal human pathogens such as Legionella pneumophila, the causative agent of Legionnaires’ disease. This bacterium...
Dobrindt, Ulrich, Michaelis, Kai, Janka, Andreas, Buchrieser, Carmen, Samuelson, Martin, Svanborg, Catharina, ...
Genomes of prokaryotes differ significantly in size and DNA composition. Escherichia coli is considered a model organism to analyze the processes involved in bacterial genome evolution, as the...
Haroche, Julien, Allignet, Jeanine, Buchrieser, Carmen, El Solh, Névine
A variant of the vga(A) gene (1,575 bp), encoding an ATP-binding cassette protein conferring resistance to streptogramin A and related antibiotics, was cloned from the chromosome of a Staphylococcus...
Buchrieser, Carmen, Rusniok, Christophe, Frangeul, Lionel, Couve, Elisabeth, Billault, Alain, Kunst, Frank, ...
We report the complete 119,443-bp sequence of the pgm locus from Yersinia pestis and its flanking regions. Sequence analysis confirms that the 102-kb unstable pgm locus is composed of two distinct...
Bach, Sandrine, Buchrieser, Carmen, Prentice, Michael, Guiyoule, Annie, Msadek, Tarek, Carniel, Elisabeth
Highly pathogenic strains of Yersinia pestis, Y. pseudotuberculosis, and Y. enterocolitica are characterized by the possession of a pathogenicity island designated the high-pathogenicity island...
Buchrieser, Carmen, Prentice, Michael, Carniel, Elisabeth
Several pathogenicity islands have recently been identified in different bacterial species, including a high-pathogenicity island (HPI) in Yersinia enterocolitica 1B. In Y. pestis, a 102-kb...
Dobrindt, Ulrich, Agerer, Franziska, Michaelis, Kai, Janka, Andreas, Buchrieser, Carmen, Samuelson, Martin, ...
Genomes of prokaryotes differ significantly in size and DNA composition. Escherichia coli is considered a model organism to analyze the processes involved in bacterial genome evolution, as the...
Doumith, Michel, Cazalet, Christel, Simoes, Natalie, Frangeul, Lionel, Jacquet, Christine, Kunst, Frank, ...
Listeria monocytogenes is a food-borne bacterial pathogen that causes a wide spectrum of diseases, such as meningitis, septicemia, abortion, and gastroenteritis, in humans and animals. Among the 13...
DNA Macroarray for Identification and Typing of Staphylococcus aureus Isolates
Trad, Salim, Allignet, Jeanine, Frangeul, Lionel, Davi, Marilyne, Vergassola, Massimo, Couve, Elisabeth, ...
A DNA macroarray containing 465 intragenic amplicons was designed to identify Staphylococcus aureus at the species level and to type S. aureus isolates. The genes selected included those encoding (i)...
Differentiation of the Major Listeria monocytogenes Serovars by Multiplex PCR
Doumith, Michel, Buchrieser, Carmen, Glaser, Philippe, Jacquet, Christine, Martin, Paul
A new multiplex PCR assay was developed to separate the four major Listeria monocytogenes serovars isolated from food and patients (1/2a, 1/2b, 1/2c, and 4b) into distinct groups. The PCR test, which...
Schneider, György, Dobrindt, Ulrich, Brüggemann, Holger, Nagy, Gábor, Janke, Britta, Blum-Oehler, Gabriele, ...
The K15 capsule determinant of uropathogenic Escherichia coli strain 536 (O6:K15:H31) is part of a novel 79.6-kb pathogenicity island (PAI) designated PAI V536 that is absent from the genome of...
Haroche, Julien, Allignet, Jeanine, Buchrieser, Carmen, El Solh, Névine
A variant of the vga(A) gene (1,575 bp), encoding an ATP-binding cassette protein conferring resistance to streptogramin A and related antibiotics, was cloned from the chromosome of a Staphylococcus...
Buchrieser, Carmen, Rusniok, Christophe, Frangeul, Lionel, Couve, Elisabeth, Billault, Alain, Kunst, Frank, ...
We report the complete 119,443-bp sequence of the pgm locus from Yersinia pestis and its flanking regions. Sequence analysis confirms that the 102-kb unstable pgm locus is composed of two distinct...
Bach, Sandrine, Buchrieser, Carmen, Prentice, Michael, Guiyoule, Annie, Msadek, Tarek, Carniel, Elisabeth
Highly pathogenic strains of Yersinia pestis, Y. pseudotuberculosis, and Y. enterocolitica are characterized by the possession of a pathogenicity island designated the high-pathogenicity island...
Buchrieser, Carmen, Prentice, Michael, Carniel, Elisabeth
Several pathogenicity islands have recently been identified in different bacterial species, including a high-pathogenicity island (HPI) in Yersinia enterocolitica 1B. In Y. pestis, a 102-kb...
Dobrindt, Ulrich, Agerer, Franziska, Michaelis, Kai, Janka, Andreas, Buchrieser, Carmen, Samuelson, Martin, ...
Genomes of prokaryotes differ significantly in size and DNA composition. Escherichia coli is considered a model organism to analyze the processes involved in bacterial genome evolution, as the...
Doumith, Michel, Cazalet, Christel, Simoes, Natalie, Frangeul, Lionel, Jacquet, Christine, Kunst, Frank, ...
Listeria monocytogenes is a food-borne bacterial pathogen that causes a wide spectrum of diseases, such as meningitis, septicemia, abortion, and gastroenteritis, in humans and animals. Among the 13...
DNA Macroarray for Identification and Typing of Staphylococcus aureus Isolates
Trad, Salim, Allignet, Jeanine, Frangeul, Lionel, Davi, Marilyne, Vergassola, Massimo, Couve, Elisabeth, ...
A DNA macroarray containing 465 intragenic amplicons was designed to identify Staphylococcus aureus at the species level and to type S. aureus isolates. The genes selected included those encoding (i)...
Differentiation of the Major Listeria monocytogenes Serovars by Multiplex PCR
Doumith, Michel, Buchrieser, Carmen, Glaser, Philippe, Jacquet, Christine, Martin, Paul
A new multiplex PCR assay was developed to separate the four major Listeria monocytogenes serovars isolated from food and patients (1/2a, 1/2b, 1/2c, and 4b) into distinct groups. The PCR test, which...
Schneider, György, Dobrindt, Ulrich, Brüggemann, Holger, Nagy, Gábor, Janke, Britta, Blum-Oehler, Gabriele, ...
The K15 capsule determinant of uropathogenic Escherichia coli strain 536 (O6:K15:H31) is part of a novel 79.6-kb pathogenicity island (PAI) designated PAI V536 that is absent from the genome of...
Brzuszkiewicz, Elzbieta, Brüggemann, Holger, Liesegang, Heiko, Emmerth, Melanie, Ölschläger, Tobias, Nagy, Gábor, ...
Uropathogenic Escherichia coli (UPEC) strain 536 (O6:K15:H31) is one of the model organisms of extraintestinal pathogenic E. coli (ExPEC). To analyze this strain's genetic basis of urovirulence, we...
Volokhov, Dmitriy V., Duperrier, Sandra, Neverov, Alexander A., George, Joseph, Buchrieser, Carmen, Hitchins, Anthony D.
The atypical hemolytic Listeria innocua strains PRL/NW 15B95 and J1-023 were previously shown to contain gene clusters analogous to the pathogenicity island (LIPI-1) present in the related foodborne...
Severino , Patricia, Dussurget , Olivier, Vêncio, Ricardo Z. N., Dumas, Emilie, Garrido, Patricia, Padilla, Gabriel, ...
Listeria monocytogenes is a food-borne, opportunistic, bacterial pathogen causing a wide spectrum of diseases, including meningitis, septicemia, abortion, and gastroenteritis, in humans and animals....
Brosch, Roland, Gordon, Stephen V., Buchrieser, Carmen, Pym, Alexander S., Garnier, Thierry, Cole, Stewart T.
On direct comparison of minimal sets of ordered clones from bacterial artificial chromosome (BAC) libraries representing the complete genomes of Mycobacterium tuberculosis H37Rv and the vaccine...
Cazalet, Christel, Jarraud, Sophie, Ghavi-Helm, Yad, Kunst, Frank, Glaser, Philippe, ...
Genomics can provide the basis for understanding the evolution of emerging, lethal human pathogens such as Legionella pneumophila, the causative agent of Legionnaires’ disease. This bacterium...
Significant Role for ladC in Initiation of Legionella pneumophila Infection▿
Newton, Hayley J., Sansom, Fiona M., Dao, Jenny, Cazalet, Christel, Bruggemann, Holger, Albert-Weissenberger, Christiane, ...
Previously, we identified ladC in a cohort of genes that were present in Legionella pneumophila but absent in other Legionella species. Here we constructed a ladC mutant of L. pneumophila and...
Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions▿ †
Tiaden, André, Spirig, Thomas, Carranza, Paula, Brüggemann, Holger, Riedel, Kathrin, Eberl, Leo, ...
The causative agent of Legionnaires' disease, Legionella pneumophila, is a natural parasite of environmental protozoa and employs a biphasic life style to switch between a replicative and a...
Camejo, Ana, Buchrieser, Carmen, Couvé, Elisabeth, Carvalho, Filipe, Reis, Olga, Ferreira, Pierre, ...
Listeria monocytogenes is a human intracellular pathogen able to colonize host tissues after ingestion of contaminated food, causing severe invasive infections. In order to gain a better...
The Legionella Autoinducer Synthase LqsA Produces an α-Hydroxyketone Signaling Molecule*S⃞
Spirig, Thomas, Tiaden, André, Kiefer, Patrick, Buchrieser, Carmen, Vorholt, Julia A., Hilbi, Hubert
The opportunistic pathogen Legionella pneumophila replicates in human lung macrophages and in free-living amoebae. To accommodate the transfer between host cells, L. pneumophila switches from a...
Rusniok, Christophe, Vallenet, David, Floquet, Stéphanie, Ewles, Helen, Mouzé-Soulama, Coralie, Brown, Daniel, ...
The genome of a clinical isolate of Neisseria meningitidis is described. This and other reannotated Neisseria genomes are compiled in a database.