Carmen García-Rodríguez

Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate (2008)

Dueñas, Ana I., Aceves, Mónica, Fernández-Pisonero, Isabel, Gómez, Cristina, Orduña, Antonio, Crespo, Mariano Sánchez, ...

Aims Vascular inflammation is a major atherogenic factor and Toll-like receptor (TLR) 2 ligands, including bacterial and serum lipoproteins, seem to be involved in atherogenesis. On this basis, we...

Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS (2006)

Dueñas, Ana I, Aceves, Mónica, Orduña, Antonio, Díaz, Ramón, Sánchez Crespo, Mariano, García-Rodríguez, Carmen

Francisella tularensis is a virulent Gram-negative intracellular pathogen. To address the signaling routes involved in the response of host cells to LPS from F. tularensis live vaccine strain (LVS),...

Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS (2006)

Dueñas, Ana I., Aceves, Mónica, Orduña, Antonio, Díaz, Ramón, Sánchez Crespo, Mariano, García-Rodríguez, Carmen

Francisella tularensis is a virulent Gram-negative intracellular pathogen. To address the signaling routes involved in the response of host cells to LPS from F. tularensis live vaccine strain (LVS),...

Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS (2004)

Dueñas, Ana I., Orduña, Antonio, Crespo, Mariano Sánchez, García-Rodríguez, Carmen

Endotoxins displaying differences in the chemical structure of their lipid A were used to induce the expression of chemokines in the human monocytic THP-1 cell line. LPS from two enterobacterial...

Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun

Macián, Fernando, García-Rodríguez, Carmen, Rao, Anjana

Cooperation between nuclear factor of activated T cells (NFAT) and AP-1 (Fos–Jun) proteins on composite NFAT–AP-1 DNA elements constitutes a powerful mechanism for signal integration of the...

Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun

Macián, Fernando, García-Rodríguez, Carmen, Rao, Anjana

Cooperation between nuclear factor of activated T cells (NFAT) and AP-1 (Fos–Jun) proteins on composite NFAT–AP-1 DNA elements constitutes a powerful mechanism for signal integration of the...

Nuclear Factor of Activated T Cells (NFAT)-dependent Transactivation Regulated by the Coactivators p300/CREB-binding Protein (CBP)

García-Rodríguez, Carmen, Rao, Anjana

p300 and cAMP response element–binding protein (CREB)–binding protein (CBP) are members of a family of coactivators involved in the regulation of transcription and chromatin. We show that...