Carmen Jerónimo

Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors (2007)

Costa, Vera L, Henrique, Rui, Ribeiro, Franclim R, Pinto, Mafalda, Oliveira, Jorge, Lobo, Francisco, ...

Abstract Background Aberrant promoter hypermethylation of cancer-associated genes occurs frequently during carcinogenesis and may serve as a cancer biomarker. In this study we aimed at defining a...

Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas (2006)

Ribeiro, Franclim R, Henrique, Rui, Hektoen, Merete, Berg, Marianne, Jerónimo, Carmen, Teixeira, Manuel R, ...

Abstract Background In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46...

P-cadherin overexpression Is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation (2005)

Paredes, Joana, Albergaria, André, Oliveira, João T., Jerónimo, Carmen, Milanezi, Fernanda, Schmitt, Fernando C.

Purpose: P-cadherin overexpressionhas been reported in breast carcinomas,where itwas associated with proliferative high-grade histological tumors. This study aimed to analyze P-cadherin expression in...

Quantitation of GSTP1 Methylation in Non-neoplastic Prostatic Tissue and Organ-Confined Prostate Adenocarcinoma (2001)

Jerónimo, Carmen, Usadel, Henning, Henrique, Rui, Oliveira, Jorge, Lopes, Carlos, Nelson, William G., ...

Background: Methylation of regulatory sequences near GSTP1, which encodes the π class glutathione S-transferase, is the most common epigenetic alteration associated with prostate cancer. We...

TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas and Paired HGPIN Lesions1

Cerveira, Nuno, Ribeiro, Franclim R, Peixoto, Ana, Costa, Vera, Henrique, Rui, Jerónimo, Carmen, ...

TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions...