Carol A. Wass

Identification and Characterization of a Novel Ibe10 Binding Protein That Contributes to Escherichia coli Invasion of Brain Microvascular Endothelial Cells

Prasadarao, Nemani V., Wass, Carol A., Huang, Sheng-He, Kim, Kwang Sik

The molecular basis of Escherichia coli traversal of the blood-brain barrier in the development of E. coli meningitis is not well understood. We have previously shown that a novel Ibe10 protein found...

Opacity-Associated Protein A Contributes to the Binding of Haemophilus influenzae to Chang Epithelial Cells

Prasadarao, Nemani V., Lysenko, Elena, Wass, Carol A., Kim, Kwang Sik, Weiser, Jeffrey N.

Opacity-associated protein A (OapA), which is responsible for the transparent-colony phenotype of Haemophilus influenzae, has been implicated in the colonization of the nasopharynx in an infant rat...

The Gene Locus yijP Contributes to Escherichia coli K1 Invasion of Brain Microvascular Endothelial Cells

Wang, Ying, Huang, Sheng-He, Wass, Carol A., Stins, Monique F., Kim, Kwang Sik

Most cases of Escherichia coli meningitis develop as a result of hematogenous spread, but it is not clear how circulating E. coli crosses the blood-brain barrier. A TnphoA mutant of E. coli K1 RS218...

Outer Membrane Protein A-Promoted Actin Condensation of Brain Microvascular Endothelial Cells Is Required for Escherichia coli Invasion

Prasadarao, Nemani V., Wass, Carol A., Stins, Monique F., Shimada, Hiroyuki, Kim, Kwang Sik

Escherichia coli is the most common gram-negative bacterium that causes meningitis during the neonatal period. We have previously shown that the entry of circulating E. coli organisms into the...

Involvement of Focal Adhesion Kinase in Escherichia coli Invasion of Human Brain Microvascular Endothelial Cells

Reddy, Marpadga A., Wass, Carol A., Kim, Kwang Sik, Schlaepfer, David D., Prasadarao, Nemani V.

Escherichia coli K1 traversal across the blood-brain barrier is an essential step in the pathogenesis of neonatal meningitis. We have previously shown that invasive E. coli promotes the actin...

Application of Signature-Tagged Mutagenesis for Identification of Escherichia coli K1 Genes That Contribute to Invasion of Human Brain Microvascular Endothelial Cells

Badger, Julie L., Wass, Carol A., Weissman, Scott J., Kim, Kwang Sik

Escherichia coli K1 is the leading cause of gram-negative bacterial meningitis in neonates. It is principally due to our limited understanding of the pathogenesis of this disease that the morbidity...

Identification and Characterization of a Novel Ibe10 Binding Protein That Contributes to Escherichia coli Invasion of Brain Microvascular Endothelial Cells

Prasadarao, Nemani V., Wass, Carol A., Huang, Sheng-He, Kim, Kwang Sik

The molecular basis of Escherichia coli traversal of the blood-brain barrier in the development of E. coli meningitis is not well understood. We have previously shown that a novel Ibe10 protein found...

Opacity-Associated Protein A Contributes to the Binding of Haemophilus influenzae to Chang Epithelial Cells

Prasadarao, Nemani V., Lysenko, Elena, Wass, Carol A., Kim, Kwang Sik, Weiser, Jeffrey N.

Opacity-associated protein A (OapA), which is responsible for the transparent-colony phenotype of Haemophilus influenzae, has been implicated in the colonization of the nasopharynx in an infant rat...

The Gene Locus yijP Contributes to Escherichia coli K1 Invasion of Brain Microvascular Endothelial Cells

Wang, Ying, Huang, Sheng-He, Wass, Carol A., Stins, Monique F., Kim, Kwang Sik

Most cases of Escherichia coli meningitis develop as a result of hematogenous spread, but it is not clear how circulating E. coli crosses the blood-brain barrier. A TnphoA mutant of E. coli K1 RS218...

Outer Membrane Protein A-Promoted Actin Condensation of Brain Microvascular Endothelial Cells Is Required for Escherichia coli Invasion

Prasadarao, Nemani V., Wass, Carol A., Stins, Monique F., Shimada, Hiroyuki, Kim, Kwang Sik

Escherichia coli is the most common gram-negative bacterium that causes meningitis during the neonatal period. We have previously shown that the entry of circulating E. coli organisms into the...

Involvement of Focal Adhesion Kinase in Escherichia coli Invasion of Human Brain Microvascular Endothelial Cells

Reddy, Marpadga A., Wass, Carol A., Kim, Kwang Sik, Schlaepfer, David D., Prasadarao, Nemani V.

Escherichia coli K1 traversal across the blood-brain barrier is an essential step in the pathogenesis of neonatal meningitis. We have previously shown that invasive E. coli promotes the actin...

Application of Signature-Tagged Mutagenesis for Identification of Escherichia coli K1 Genes That Contribute to Invasion of Human Brain Microvascular Endothelial Cells

Badger, Julie L., Wass, Carol A., Weissman, Scott J., Kim, Kwang Sik

Escherichia coli K1 is the leading cause of gram-negative bacterial meningitis in neonates. It is principally due to our limited understanding of the pathogenesis of this disease that the morbidity...