Carol Sibley

Publication List Details

Period

2001 - 2008

Number

6

Co-Authors

Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase (2008)

Hawkins, Vivian N, Auliff, Alyson, Prajapati, Surendra, Rungsihirunrat, Kanchana, Hapuarachchi, Hapuarachchige C, Maestre, Amanda, ...

Abstract Background In order to maximize the useful therapeutic life of antimalarial drugs, it is crucial to understand the mechanisms by which parasites resistant to antimalarial drugs are selected...

World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility (2007)

Bacon, David J, Jambou, Ronan, Fandeur, Thierry, Le Bras, Jacques, Wongsrichanalai, Chansuda, Fukuda, Mark M, ...

Abstract Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and...

A database of antimalarial drug resistance (2006)

Sibley, Carol, Ringwald, Pascal

Abstract A large investment is required to develop, license and deploy a new antimalarial drug. Too often, that investment has been rapidly devalued by the selection of parasite populations resistant...