Caroline E. Gargett

Clonogenicity of Human Endometrial Epithelial and Stromal Cells1 (2004)

Kjiana E. Schwab, Caroline E. Gargett

The human endometrium regenerates from the lower basalis layer, a germinal compartment that persists after menstruation to give rise to the new upper functionalis layer. Because adult stem cells are...

Fibroids display an anti-angiogenic gene expression profile when compared with adjacent myometrium (2003)

Weston, Gareth, Trajstman, Albert C., Gargett, Caroline E., Manuelpillai, Ursula, Vollenhoven, Beverley J., Rogers, Peter A.W.

The aetiology of uterine fibroids remains unknown, despite causing significant gynaecological morbidity. Fibroids have a reduced microvascular density when compared with adjacent myometrial tissue....

Estrogen receptor-{alpha} and -{beta} expression in microvascular endothelial cells and smooth muscle cells of myometrium and leiomyoma (2002)

Gargett, Caroline E., Bucak, Kristina, Zaitseva, Marina, Chu, Simon, Taylor, Nancy, Fuller, Peter J., ...

The two estrogen receptors, ERα and ERβ, are likely to have roles in the pathophysiology of fibroid development. They have been detected in myometrial and leiomyoma (fibroid) tissue, but the cell...

Focal vascular endothelial growth factor correlates with angiogenesis in human endometrium. Role of intravascular neutrophils (2001)

Gargett, Caroline E., Lederman, Fiona, Heryanto, Bambang, Gambino, Lara S., Rogers, Peter A.W.

Vascular endothelial growth factor (VEGF) is expressed in human endometrium, but the cellular source of VEGF for endometrial angiogenesis has not been determined. In the present study the...

The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

Gargett, Caroline E, Wiley, James S

Extracellular adenosine 5′-triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of a cation-selective ion channel, activation of phospholipase D and...

ATP, a partial agonist for the P2Z receptor of human lymphocytes

Gargett, Caroline E, Cornish, Jean E, Wiley, James S

Although extracellular adenosine 5′-triphosphate (ATP) is the natural ligand for the P2Z receptor of human lymphocytes it is less potent than 3′-O-(4-benzoylbenzoyl)-ATP (BzATP) in opening the...