Scientific Commons: Caroline Hayward

Genome-wide Association Study of Anthropometric Traits in Korčula Island, Croatia (2009)

Polašek, Ozren; Adrija Štampar School Of Public Health, Zagreb, Croatia, Marušić, Ana; School Of Medicine, University Of Split, Croatia, Rotim, Krešimir; Sisters Of Mercy University Hospital, Zagreb, Croatia, Hayward, Caroline; Human Genetics Unit, Western General Hospital, Edinburg, UK, Vitart, Veronique; Human Genetics Unit, Western General Hospital, Edinburg, UK, Huffman, Jennifer; Human Genetics Unit, Western General Hospital, Edinburg, UK, ...

Aim To identify genetic variants underlying six anthropometric traits: body height, body weight, body mass index, brachial circumference, waist circumference, and hip circumference, using a...

Genome-wide Association Study of Biochemical Traits in Korčula Island, Croatia (2009)

Zemunik, Tatijana; School Of Medicine, University Of Split, Split, Croatia, Boban, Mladen; School Of Medicine, University Of Split, Split, Croatia, Lauc, Gordan; School Of Medicine, University Of Split, Split, Croatia, Janković, Stipan; School Of Medicine, University Of Split, Split, Croatia, Rotim, Krešimir; Sisters Of Mercy University Hospital, Zagreb, Croatia, Vatavuk, Zoran; Sisters Of Mercy University Hospital, Zagreb, Croatia, ...

Aim To identify genetic variants underlying biochemical traits – total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, uric acid,...

Historic, Demographic, and Genetic Evidence for Increased Population Frequencies of CCR5Δ32 Mutation in Croatian Island Isolates after Lethal 15th Century Epidemics (2009)

Biloglav, Zrinka; Andrija Štampar School Of Public Health, School Of Medicine, University Of Zagreb, Croatia; Zrinka23@yahoo.com, Zgaga, Lina; Andrija Štampar School Of Public Health, School Of Medicine, University Of Zagreb, Croatia, Smoljanović, Mladen; School Of Medicine, University Of Split, Croatia, Hayward, Caroline; Human Genetics Unit, Western General Hospital, Edinburg, UK, Polašek, Ozren; Andrija Štampar School Of Public Health, School Of Medicine, University Of Zagreb, Croatia, Kolčić, Ivana; Andrija Štampar School Of Public Health, School Of Medicine, University Of Zagreb, Croatia, ...

Aim To assess the frequency of 32 base pair deletion in CCR5 (CCR5Δ32), which has been shown to confer resistance to HIV infection in a homozygous form, in 10 isolated island communities of...

Genome-wide association study identifies _FUT8_ and _ESR2_ as co-regulators of a bi-antennary N-linked glycan A2 (GlcNAc~2~Man~3~GlcNAc~2~) in human plasma proteins (2009)

Gordan Lauc, Jennifer Huffman, Caroline Hayward, Ana Knezevic, Ozren Polasek, Olga Gornik, ...

HPLC analysis of N-glycans quantified levels of the biantennary glycan (A2) in plasma proteins of 924 individuals. Subsequent genome-wide association study (GWAS) using 317,503 single nucleotide...

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis (2009)

Johansson, Åsa, Marroni, Fabio, Hayward, Caroline, Franklin, Christopher S., Kirichenko, Anatoly V., Jonasson, Inger, ...

Genes for height have gained interest for decades, but only recently have candidate genes started to be identified. We have performed linkage analysis and genome-wide association for height in...

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition (2007)

Harris, Sarah E, Fox, Helen, Wright, Alan F, Hayward, Caroline, Starr, John M, Whalley, Lawrence J, ...

Abstract Background Non-pathological cognitive ageing is a distressing condition affecting an increasing number of people in our 'ageing society'. Oxidative stress is hypothesised to have a major...

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits (2007)

Campbell, Harry, Carothers, Andrew D., Rudan, Igor, Hayward, Caroline, Biloglav, Zrinka, Barac, Lovorka, ...

The dramatic changes in human population structure over the last 200 years have resulted in significant levels of outbreeding, which, in turn, is predicted to lead to increased levels of individual...

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits (2007)

Campbell, Harry, Carothers, Andrew D., Rudan, Igor, Hayward, Caroline, Biloglav, Zrinka, Barac, Lovorka, ...

The dramatic changes in human population structure over the last 200 years have resulted in significant levels of outbreeding which in turn is predicted to lead to increased levels of individual...

Historic Exposure to Plague and Present-day Frequency of CCR5del32 in Two Isolated Island Communities of Dalmatia, Croatia (2006)

Smoljanović, Mladen, Ristić, Smiljana, Hayward, Caroline

Aim: To assess the frequency of deletion of 32 base pairs in a CCR5 gene, shown to confer resistance to HIV infection, in two isolated island communities of Dalmatia, Croatia, with different...

Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5 (2006)

Shu, Xinhua, Tulloch, Brian, Lennon, Alan, Vlachantoni, Dafni, Zhou, Xinzhi, Hayward, Caroline, ...

Late-onset retinal macular degeneration (L-ORMD) is an autosomal dominant condition resembling age-related macular degeneration (AMD) in which a key pathological feature is a thick extracellular...

Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5 (2006)

Shu, Xinhua, Tulloch, Brian, Lennon, Alan, Vlachantoni, Dafni, Zhou, Xinzhi, Hayward, Caroline, ...

Late-onset retinal macular degeneration (L-ORMD) is an autosomal dominant condition resembling age-related macular degeneration (AMD) in which a key pathological feature is a thick extracellular...

Lost in Transition – The Island of Susak (1951–2001) (2004)

Rudan, Igor, Stevanović, Ranko, Vitart, Veronique, Vuletić, Gorka, Sibbett, Lorna, Vuletić, Silvije, ...

The isolated population of the Island of Susak was thoroughly studied by a multidisciplinary team of the Croatian Academy of Sciences and Arts in early 1950’s. Recently, a team of scientists...

Identification of SATB2 as the cleft palate gene on 2q32-q33 (2003)

FitzPatrick, David R., Carr, Ian M., McLaren, Lorna, Leek, Jack P., Wightman, Patrick, Williamson, Kathy, ...

Cytogenetic evidence, in the form of deletions and balanced translocations, points to the existence of a locus on 2q32-q33, for which haploinsufficiency results in isolated cleft palate (CPO). Here...

Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration - a genetic model for age-related macular degeneration (2003)

Hayward, Caroline, Shu, Xinhua, Cideciyan, Artur V, Lennon, Alan, Barran, Perdita, Zareparsi, Sepideh, ...