Pauli, Eva-K, Schmolke, Mirco, Hofmann, Henning, Ehrhardt, Christina, Flory, Egbert, Münk, Carsten, ...
Abstract Human APOBEC3G is an antiretroviral protein that was described to act via deamination of retroviral cDNA. However, it was suggested that APOBEC proteins might act with antiviral activity by...
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes (2008)
Münk, Carsten, Beck, Thomas, Zielonka, Jörg, Hotz-Wagenblatt, Agnes, Chareza, Sarah, Battenberg, Marion, ...
Abstract Background Over the past years a variety of host restriction genes have been identified in human and mammals that modulate retrovirus infectivity, replication, assembly, and/or cross-species...
Sp1 and Sp3 regulate basal transcription of the human APOBEC3G gene (2007)
Muckenfuss, Heide, Kaiser, Julia K., Krebil, Erika, Battenberg, Marion, Schwer, Christina, Cichutek, Klaus, ...
APOBEC3G (A3G), a member of the recently discovered family of human cytidine deaminases, is expressed in peripheral blood lymphocytes and has been shown to be active against HIV-1 and other...
Vaccinia virus replication is not affected by APOBEC3 family members (2006)
Kremer, Melanie, Suezer, Yasemin, Martinez-Fernandez, Yolanda, Münk, Carsten, Sutter, Gerd, Schnierle, Barbara S
Abstract Background The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA...
Amphotropic murine leukemia viruses induce spongiform encephalomyelopathy
Münk, Carsten, Löhler, Jürgen, Prassolov, Vladimir, Just, Ursula, Stockschläder, Marcus, Stocking, Carol
Recombinants of amphotropic murine leukemia virus (A-MuLV) have found widespread use in retroviral vector systems due to their ability to efficiently and stably infect cells of several different...
Mus cervicolor Murine Leukemia Virus Isolate M813 Belongs to a Unique Receptor Interference Group
Prassolov, Vladimir, Hein, Sibyll, Ziegler, Marion, Ivanov, Dmitry, Münk, Carsten, Löhler, Jürgen, ...
Murine leukemia virus (MuLV) M813 was originally isolated from the Southeast Asian rodent Mus cervicolor. As with the ecotropic MuLVs derived from Mus musculus, its host range is limited to rodent...
A dominant block to HIV-1 replication at reverse transcription in simian cells
Münk, Carsten, Brandt, Stephanie M., Lucero, Ginger, Landau, Nathaniel R.
Although nonhuman primates are genetically close to humans, their T cells do not support productive replication of HIV-1. In contrast, HIV-1 replicates in activated human CD4+ T cells, monocytes, and...
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
Kootstra, Neeltje A., Münk, Carsten, Tonnu, Nina, Landau, Nathaniel R., Verma, Inder M.
HIV-1 replication in simian cells is restricted at an early postentry step because of the presence of an inhibitory cellular factor. This block reduces the usefulness of HIV-1-based lentiviral...
Day, John R., Münk, Carsten, Guatelli, John C.
The membrane-proximal tyrosine-based sorting motif in the cytoplasmic domain of the human immunodeficiency virus type 1 Env glycoprotein is important for endocytosis from the plasma membrane,...
The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein
Löchelt, Martin, Romen, Fabian, Bastone, Patrizia, Muckenfuss, Heide, Kirchner, Nadine, Kim, Yong-Boum, ...
Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been observed. Lentiviruses like HIV-1 have...
Vaccinia virus replication is not affected by APOBEC3 family members
Kremer, Melanie, Suezer, Yasemin, Martinez-Fernandez, Yolanda, Münk, Carsten, Sutter, Gerd, Schnierle, Barbara S
Amphotropic murine leukemia viruses induce spongiform encephalomyelopathy
Münk, Carsten, Löhler, Jürgen, Prassolov, Vladimir, Just, Ursula, Stockschläder, Marcus, Stocking, Carol
Recombinants of amphotropic murine leukemia virus (A-MuLV) have found widespread use in retroviral vector systems due to their ability to efficiently and stably infect cells of several different...
Mus cervicolor Murine Leukemia Virus Isolate M813 Belongs to a Unique Receptor Interference Group
Prassolov, Vladimir, Hein, Sibyll, Ziegler, Marion, Ivanov, Dmitry, Münk, Carsten, Löhler, Jürgen, ...
Murine leukemia virus (MuLV) M813 was originally isolated from the Southeast Asian rodent Mus cervicolor. As with the ecotropic MuLVs derived from Mus musculus, its host range is limited to rodent...
A dominant block to HIV-1 replication at reverse transcription in simian cells
Münk, Carsten, Brandt, Stephanie M., Lucero, Ginger, Landau, Nathaniel R.
Although nonhuman primates are genetically close to humans, their T cells do not support productive replication of HIV-1. In contrast, HIV-1 replicates in activated human CD4+ T cells, monocytes, and...
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
Kootstra, Neeltje A., Münk, Carsten, Tonnu, Nina, Landau, Nathaniel R., Verma, Inder M.
HIV-1 replication in simian cells is restricted at an early postentry step because of the presence of an inhibitory cellular factor. This block reduces the usefulness of HIV-1-based lentiviral...
Day, John R., Münk, Carsten, Guatelli, John C.
The membrane-proximal tyrosine-based sorting motif in the cytoplasmic domain of the human immunodeficiency virus type 1 Env glycoprotein is important for endocytosis from the plasma membrane,...
The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein
Löchelt, Martin, Romen, Fabian, Bastone, Patrizia, Muckenfuss, Heide, Kirchner, Nadine, Kim, Yong-Boum, ...
Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been observed. Lentiviruses like HIV-1 have...
Vaccinia virus replication is not affected by APOBEC3 family members
Kremer, Melanie, Suezer, Yasemin, Martinez-Fernandez, Yolanda, Münk, Carsten, Sutter, Gerd, Schnierle, Barbara S
Sp1 and Sp3 regulate basal transcription of the human APOBEC3G gene
Muckenfuss, Heide, Kaiser, Julia K., Krebil, Erika, Battenberg, Marion, Schwer, Christina, Cichutek, Klaus, ...
APOBEC3G (A3G), a member of the recently discovered family of human cytidine deaminases, is expressed in peripheral blood lymphocytes and has been shown to be active against HIV-1 and other...
Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells▿
Münk, Carsten, Zielonka, Jörg, Constabel, Hannelore, Kloke, Björn-Philipp, Rengstl, Benjamin, Battenberg, Marion, ...
The productive replication of human immunodeficiency virus type 1 (HIV-1) occurs exclusively in defined cells of human or chimpanzee origin, explaining why heterologous animal models for HIV...
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes
Münk, Carsten, Beck, Thomas, Zielonka, Jörg, Hotz-Wagenblatt, Agnes, Chareza, Sarah, Battenberg, Marion, ...
APOBEC3 (A3, Apolipoprotein B mRNA-editing catalytic polypeptide 3) genes in the genome of domestic cat (Felis catus) were identified and characterized
Pauli, Eva-K, Schmolke, Mirco, Hofmann, Henning, Ehrhardt, Christina, Flory, Egbert, Münk, Carsten, ...
Human APOBEC3G is an antiretroviral protein that was described to act via deamination of retroviral cDNA. However, it was suggested that APOBEC proteins might act with antiviral activity by yet other...