Carsten Rosenow

RNAHalfWjEC (2007)

Reveals Positional Patternsof, Douglas W. Selinger, Rini Mukherjee Saxena, Kevin J. Cheung, George M. Church, Carsten Rosenow

tionof its abundance and degradation. We discuss the applicationof subgenic resolution DNA microarray analysis to study global mechanismsof RNA transcription and processing. Gene regulatiB i adynami...

Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data (2005)

Leykin, Igor, Hao, Ke, Cheng, Junsheng, Meyer, Nicole, Pollak, Martin R, Smith, Richard JH, ...

Abstract Background The identification of disease-associated genes using single nucleotide polymorphisms (SNPs) has been increasingly reported. In particular, the Affymetrix Mapping 10 K SNP...

Global RNA Half-Life Analysis in Escherichia coli Reveals Positional Patterns of Transcript Degradation (2003)

Selinger, Douglas W., Saxena, Rini Mukherjee, Cheung, Kevin J., Church, George M., Rosenow, Carsten

Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655. RNA chemical half-lives were measured for 1036 open reading frames...

Identifying operons and untranslated regions of transcripts using Escherichia coli RNA expression analysis (2002)

Tjaden, Brian, Haynor, David R., Stolyar, Sergey, Rosenow, Carsten, Kolker, Eugene

Microarrays traditionally have been used to assay the transcript expression of coding regions of genes. Here, we use Escherichia coli oligonucleotide microarrays to assay transcript expression of...

Transcriptome analysis of Escherichia coli using high-density oligonucleotide probe arrays (2002)

Tjaden, Brian, Saxena, Rini Mukherjee, Stolyar, Sergey, Haynor, David R., Kolker, Eugene, Rosenow, Carsten

Microarrays traditionally have been used to analyze the expression behavior of large numbers of coding transcripts. Here we present a comprehensive approach for high‐throughput transcript...

Prokaryotic RNA preparation methods useful for high density array analysis: comparison of two approaches (2001)

Rosenow, Carsten, Saxena, Rini Mukherjee, Durst, Mark, Gingeras, Thomas R.

High density oligonucleotide arrays have been used extensively for expression studies of eukaryotic organisms. We have designed a prokaryotic high density oligonucleotide array using the complete...

Prokaryotic RNA preparation methods useful for high density array analysis: comparison of two approaches

Rosenow, Carsten, Saxena, Rini Mukherjee, Durst, Mark, Gingeras, Thomas R.

High density oligonucleotide arrays have been used extensively for expression studies of eukaryotic organisms. We have designed a prokaryotic high density oligonucleotide array using the complete...

Transcriptome analysis of Escherichia coli using high-density oligonucleotide probe arrays

Tjaden, Brian, Saxena, Rini Mukherjee, Stolyar, Sergey, Haynor, David R., Kolker, Eugene, Rosenow, Carsten

Microarrays traditionally have been used to analyze the expression behavior of large numbers of coding transcripts. Here we present a comprehensive approach for high-throughput transcript discovery...

Regulation of the α-Galactosidase Activity in Streptococcus pneumoniae: Characterization of the Raffinose Utilization System

Rosenow, Carsten, Maniar, Mita, Trias, Joaquim

A 10.2-kb gene region was identified in the Streptococcus pneumoniae genome sequence that contains eight genes involved in regulation and metabolism of raffinose. The genes rafR and rafS are...

Global RNA Half-Life Analysis in Escherichia coli Reveals Positional Patterns of Transcript Degradation

Selinger, Douglas W., Saxena, Rini Mukherjee, Cheung, Kevin J., Church, George M., Rosenow, Carsten

Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655. RNA chemical half-lives were measured for 1036 open reading frames...

Identification of novel small RNAs using comparative genomics and microarrays

Wassarman, Karen M., Repoila, Francis, Rosenow, Carsten, Storz, Gisela, Gottesman, Susan

A burgeoning list of small RNAs with a variety of regulatory functions has been identified in both prokaryotic and eukaryotic cells. However, it remains difficult to identify small RNAs by sequence...

Prokaryotic RNA preparation methods useful for high density array analysis: comparison of two approaches

Rosenow, Carsten, Saxena, Rini Mukherjee, Durst, Mark, Gingeras, Thomas R.

High density oligonucleotide arrays have been used extensively for expression studies of eukaryotic organisms. We have designed a prokaryotic high density oligonucleotide array using the complete...

Transcriptome analysis of Escherichia coli using high-density oligonucleotide probe arrays

Tjaden, Brian, Saxena, Rini Mukherjee, Stolyar, Sergey, Haynor, David R., Kolker, Eugene, Rosenow, Carsten

Microarrays traditionally have been used to analyze the expression behavior of large numbers of coding transcripts. Here we present a comprehensive approach for high-throughput transcript discovery...

Regulation of the α-Galactosidase Activity in Streptococcus pneumoniae: Characterization of the Raffinose Utilization System

Rosenow, Carsten, Maniar, Mita, Trias, Joaquim

A 10.2-kb gene region was identified in the Streptococcus pneumoniae genome sequence that contains eight genes involved in regulation and metabolism of raffinose. The genes rafR and rafS are...

Identification of novel small RNAs using comparative genomics and microarrays

Wassarman, Karen M., Repoila, Francis, Rosenow, Carsten, Storz, Gisela, Gottesman, Susan

A burgeoning list of small RNAs with a variety of regulatory functions has been identified in both prokaryotic and eukaryotic cells. However, it remains difficult to identify small RNAs by sequence...

Global RNA Half-Life Analysis in Escherichia coli Reveals Positional Patterns of Transcript Degradation

Selinger, Douglas W., Saxena, Rini Mukherjee, Cheung, Kevin J., Church, George M., Rosenow, Carsten

Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655. RNA chemical half-lives were measured for 1036 open reading frames...

Comparison of Microsatellites Versus Single-Nucleotide Polymorphisms in a Genome Linkage Screen for Prostate Cancer–Susceptibility Loci

Schaid, Daniel J., Guenther, Jennifer C., Christensen, Gerald B., Hebbring, Scott, Rosenow, Carsten, Hilker, Christopher A., ...

Prostate cancer is one of the most common cancers among men and has long been recognized to occur in familial clusters. Brothers and sons of affected men have a 2–3-fold increased risk of...