Carter Van Waes

Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status (2008)

Yan, Bin, Chen, Guang, Saigal, Kunal, Yang, Xinping, Jensen, Shane T, Van Waes, Carter, ...

Abstract Background Aberrant activation of the nuclear factor kappaB (NF- κ B) pathway has been previously implicated as a crucial signal promoting tumorigenesis. However, how NF- κ B acts as a key...

Autocrine and Paracrine Chemokine Receptor 7 Activation in Head and Neck Cancer: Implications for Therapy (2008)

Wang, Jun, Seethala, Raja R., Zhang, Qing, Gooding, William, Van Waes, Carter, Hasegawa, Hitoshi, ...

Background The chemokine receptor 7 (CCR7) mediates survival and invasiveness of metastatic squamous cell carcinoma of the head and neck (SCCHN) to regional lymph nodes. Constitutive prosurvival...

Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma (2007)

Yan, Bin, Yang, Xinping, Lee, Tin-Lap, Friedman, Jay, Tang, Jun, Van Waes, Carter, ...

Abstract Background Differentially expressed gene profiles have previously been observed among pathologically defined cancers by microarray technologies, including head and neck squamous cell...

Blood group antigens and integrins as biomarkers in head and neck cancer: Is aberrant tyrosine phosphorylation the cause of altered Α6Β4 integrin expression? (1993)

Carey, Thomas E., Nair, Thankam S., Chern, Catherine, Liebert, Monica, Grossman, H. Barton, Wolf, Gregory T., ...

Head and neck cancer is a capricious disease that varies greatly in its clinical behavior. The development of biomarkers that can distinguish between biologically aggressive and indolent tumors has...

Monoclonal antibodies to inner ear antigens: I. Antigens expressed by supporting cells of the guinea pig cochlea (1991)

Zajic, Gary, Nair, Thankam S., Ptok, Martin, Van Waes, Carter, Altschuler, Richard A., Schacht, Jochen, ...

Murine monoclonal antibodies against guinea pig cochlear epithelium were generated with the goal of identifying cochlea-specific antigens and elucidating their function. To compensate for the limited...

Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma

Yan, Bin, Yang, Xinping, Lee, Tin-Lap, Friedman, Jay, Tang, Jun, Van Waes, Carter, ...

Microarray profiling of ten head and neck cancer lines revealed novel p53 and NF-κB transcriptional gene expression signatures which distinguished tumor cell subsets in association with their p53...

Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status

Yan, Bin, Chen, Guang, Saigal, Kunal, Yang, Xinping, Jensen, Shane T, Van Waes, Carter, ...

Detailed analysis of NFκB regulons in 1,265 genes differentially expressed in head and neck cancer cell lines differing in p53 status revealed a cross talk between NFkB and specific signaling...